Streptomyces sp. VB1: OH133_27475
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Entry
OH133_27475 CDS
T11054
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
stvb Streptomyces sp. VB1
Pathway
stvb00010
Glycolysis / Gluconeogenesis
stvb00020
Citrate cycle (TCA cycle)
stvb00620
Pyruvate metabolism
stvb00785
Lipoic acid metabolism
stvb01100
Metabolic pathways
stvb01110
Biosynthesis of secondary metabolites
stvb01120
Microbial metabolism in diverse environments
stvb01200
Carbon metabolism
stvb01210
2-Oxocarboxylic acid metabolism
Module
stvb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
stvb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
OH133_27475 (aceE)
00020 Citrate cycle (TCA cycle)
OH133_27475 (aceE)
00620 Pyruvate metabolism
OH133_27475 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
OH133_27475 (aceE)
Enzymes [BR:
stvb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
OH133_27475 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
UZI31529
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Position
complement(6127189..6129921)
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AA seq
910 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETREWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGDEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDQGDGGDQIFFQGHASPGIYARAFLLDRLSEAQLDGFRQ
EKSKAPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIYQARMNRYMEARGIADTSKSHVW
AYLGDGEMDEPESLGQLSIAARENLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRTGILVNRLNTTPDGQFQTYATETGEYIREHFFGDDPRLR
DMVKDMTDQQILHLGRGGHDHRKVYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTVEDLKRFRDRLHIPITDKQLDEGYPPYYHPGRDSEEIQYMHDRRQGLGGYVP
TRVVRAKPLPQPEEKTYAAAKKGSGTQSIATTMAFVRVLKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYEAVDRDLLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAYGFEIAHIMKDGLRRMYGEANEDVFYYLTVYNEPIQHPAEPE
DVDVEGILKGIHRFSTGEKGEIPAQIMASGVAVPWALEAQKILADEWNVKADVWSATSWN
ELRREAVDVERYNLLHPEEEQRVPYVTKKLEAAQGPFVAVSDWMRSVPDQIARWVPGAYQ
SLGADGFGFADTRGAARRFFHIDAQSIVLAVLTELAKEGKVDRSALKTAVDRYELLDVAA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttccgagccaggtcccg
gattttgatcccgaggagacccgggaatggctcgactccctcgacgccgccgtcgacgag
cgcggccgagagcgggcccgctatctgatgctccggctcatcgagcgcgcgcgggagaag
cgcgtcgcggtgccggagatgcgcagcacggactatgtgaacacgatcgccacgaaggac
gagccgttcttccccggcgacgaggagatcgaacgcaaggtcctcaacgcgacgcgctgg
aacgccgcggtgatggtctcgcgggcccagcgtcccgggatcggcgtcggcggccacatc
gccaccttcgcttcctccgcctcgctgtacgacgtgggcttcaaccacttcttccggggc
aaggaccagggcgacggcggcgaccagatcttcttccagggacacgcgtccccggggatc
tacgcccgggcgttcctgctggaccggctgagcgaggcgcagctcgacgggttccgccag
gagaagtcgaaggccccgaacgggctgtccagctatccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtctcgatgggcctcggtccgctcggcgcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggcatcgccgacacctccaagtcgcacgtgtgg
gcctatctgggcgacggcgagatggacgagccggagtccctgggccagctgtccatcgcg
gcccgtgagaatctggacaacctgaccttcgtggtcaactgcaacctccagcgcctcgac
ggcccggtgcgcggcaacgggaagatcatccaggagctggagtcgcagttccggggcgcc
ggctggaacgtcatcaagctggtctgggaccgttcctgggacccgctgctggcgcaggac
cgcaccggcatcctggtcaacaggctgaacaccacgccggacggtcagttccagacgtac
gccaccgagaccggcgagtacatccgcgagcacttcttcggcgacgacccgcggctgcgg
gacatggtcaaggacatgaccgaccagcagatcctgcacctgggccgcggcggtcacgac
caccgcaaggtctacgcggcctacgcggcggccaaggcgcacaagggccagccgacggtg
atcctggcgcagacggtcaagggctggacgctggggccgaacttcgagggccgcaacgcg
acccaccagatgaagaagctcacggtcgaggacctcaagcgcttccgcgaccggctgcac
atcccgatcacggacaagcagctggacgagggctacccgccctactaccacccgggtcgc
gactcggaggagatccagtacatgcacgaccgccgccagggtctgggcggttacgtcccg
acccgtgtggtgcgtgcgaagccgcttccgcagcccgaggaaaagacgtacgcggctgcg
aagaagggttcgggtacgcagtcgatcgccaccaccatggcgttcgtccgcgtcctgaag
gatctcatgcgggacaaggagatcggcaagcgtttcgtgctgatcgcccctgatgagtac
cgcaccttcggcatggacgcgttcttcccgagtgcgaagatttacaacccgctcggccag
cagtacgaggcggtcgaccgcgatctgctgctcgcgtacaaggagtccccgacgggtcag
atgctgcacgacggcatctccgaggcgggctgcacggcctcgctgatcgcggccggctcc
gcgtacgccacgcacggcgagccgctgatcccggtgtacgtcttctactcgatgttcggg
ttccagcgcaccggcgaccagttctggcagatggccgaccagctcgcgcgcggcttcgtg
ctcggcgcgaccgccggccgcaccacgctgaccggtgagggcctccagcacgcggacggc
cactcgcagctgctcgcctcgacgaacccgggctgtgtcgcgtacgacccggcgtacggg
ttcgagatcgcgcacatcatgaaggacgggctgcgccggatgtacggcgaggcgaacgag
gacgtcttctactacctcaccgtctacaacgagccgatccagcacccggccgagcccgag
gatgtggacgtcgagggcatcctcaagggcatccaccgcttcagcaccggcgagaagggc
gagatcccggcccagatcatggcgtccggtgtggccgtcccctgggccctggaggcgcag
aagatcctcgcggacgagtggaacgtcaaggcggacgtctggtcggcgacctcctggaac
gagctgcgccgcgaggcggtggacgtcgagcgctacaacctcctgcacccggaggaggag
cagcgcgtcccgtacgtcacgaagaagctcgaagcggcccagggcccgttcgtggcggtc
tcggactggatgcgttcggttccggaccagatcgcgcgctgggtgccgggcgcctaccag
tcgctgggcgcggacggcttcggcttcgcggacacccggggtgcggcccgccggttcttc
cacatcgacgcgcagtcgatcgtgctggcggtcctcaccgagctggccaaggagggcaag
gtcgaccggtcggccctgaagacggcggtggaccgctacgagctcctggacgtggccgcg
gccgatccgggcgcggcgggcggcgacgcgtag
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