KEGG   Salmonella enterica subsp. enterica serovar Typhi CT18: STY4405
Entry
STY4405           CDS       T00064                                 
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
sty  Salmonella enterica subsp. enterica serovar Typhi CT18
Pathway
sty00270  Cysteine and methionine metabolism
sty00450  Selenocompound metabolism
sty00670  One carbon pool by folate
sty01100  Metabolic pathways
sty01110  Biosynthesis of secondary metabolites
sty01230  Biosynthesis of amino acids
sty04981  Folate transport and metabolism
Module
sty_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:sty00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    STY4405
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    STY4405
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    STY4405
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    STY4405
   04980 Cobalamin transport and metabolism
    STY4405
Enzymes [BR:sty01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     STY4405
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: CAD09193
UniProt: A0A718AKU3 Q8Z1V6
LinkDB
Position
4270729..4274412
AA seq 1227 aa
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTA
RTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILI
ETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVAGLSPRQLPDIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRERKIEICRRAYKILLEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDNLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGSKTDEAASAQQAEWRSWDVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHARKKPR
TPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLKEDALADAFEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV
TDYAFRKGMSVEDVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagttgaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcaccatgatccagagctatcgtctacatgaagaagatttccgcggggag
cgctttgccgactggccctgcgacctgaaaggcaacaatgacctgctggtcctcagcaag
ccggaggtgatcgccgctatccacaacgcctactttgaggctggcgcggatatcatcgaa
accaacacctttaactcgacaaccattgcgatggcggattaccggatggaatccctgtcg
gcggaaattaactatgcggcggccaaactggcgcgcgcctgcgccgatgaatggacggcg
cgaacaccagaaaaaccacgctttgttgcgggcgtgcttggtccaactaaccgcacggcc
tccatttcgccggacgtcaacgacccggcgtttcgtaatatcaccttcgatcagctggtg
gcggcctaccgtgaatccaccaaagcgctggtggaaggcggggcggacctgatcctgatt
gaaactgtcttcgacaccctcaacgccaaagcggcggtgtttgcggtgaaagaagagttt
gaagcgctgggcgttgatctgccgatcatgatttccggcaccatcaccgacgcctctggc
cgtacgctttccggccagacgaccgaagccttttataactcgctgcgccacgccgaggcg
ctcacttttggccttaactgcgcgctggggccagatgaactgcgccagtacgtccaggaa
ctgtcgcggattgccgaatgctacgtcaccgcgcacccgaacgccggcctgccgaacgct
ttcggcgagtacgacctcgacgccgacaccatggcgaaacagattcgcgaatgggcggaa
gcgggcttcctgaatatcgttggcggctgctgcggcaccacgccggagcatattgcggcg
atgagccgcgccgttgccggtttgtcgccgcgccagctgccggatatcccggtggcctgc
cgcctttccggcctggagccgctgaacattggtgacgatagcctgtttgtcaacgtcggc
gaacgtactaacgtcaccggctcggccaaatttaaacgcttgatcaaagaagagaaatac
agcgaagcgctggatgtcgcccgtcagcaggtcgaaagcggcgcgcagattattgatatc
aatatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcagcctgatt
gccggtgagccggacattgcccgtgtaccaatcatgattgactcctccaaatgggaggtt
atcgaaaaagggctgaagtgcattcagggtaaaggcatcgtcaactctatttcgatgaaa
gagggcgtggaagcctttattcatcatgcgaagttgctacgtcgctacggcgccgcagtg
gtggtgatggcttttgatgagcaggggcaggccgacacccgcgaacgtaaaatcgagatt
tgccgccgcgcttacaaaattttgctcgaagaggtaggctttccgccggaagacatcatc
ttcgacccgaatatcttcgccgtcgccaccggtattgaagagcacaacaactacgcgcag
gactttatcggcgcttgtgaagacatcaaacgcgagctgccgcacgcgctgatctccggc
ggcgtgtctaacgtgtccttctcgtttcgcggcaacgacccggtacgtgaggctatccac
gcggtattcctctactacgccatccgcaacggcatggacatgggcatcgtcaacgccggg
caactggcgatttatgacaacctgcctgccgaactgcgcgatgcagttgaagatgtcatt
cttaaccgtcgcgatgacggcaccgagcgtttgctggatttggcggagaaatatcgcggc
agcaaaaccgacgaggctgccagtgcccagcaggcggaatggcgtagctgggacgtgaaa
aagcgtctcgaatactcgctggtgaaaggcattaccgagtttatcgaacaggataccgaa
gaagcccgtcagcaggccgcccgcccgattgaggtgattgaagggccgctgatggacggc
atgaacgtggtcggcgacctgttcggcgaagggaaaatgttcctgccgcaggtggtgaaa
tccgctcgcgtgatgaaacaagcggtggcctacctggagccgtttattgaagccagcaaa
gaaaaaggctccagcaacggcaagatggtgattgccaccgtgaagggcgatgtgcacgac
attggcaagaacattgtcggcgtggtgctgcaatgcaacaactacgaaatcgtcgatctt
ggcgtgatggtgccagcggagaaaatcctcagaacggcgcgtgaagtgaatgccgatctg
attggtctttccgggcttatcaccccgtcgctggacgaaatggtcaacgtggcgaaagag
atggagcgtcagggctttactatcccgctactgatcggcggcgcaaccacttcgaaagcg
catacggcggtgaaaatcgagcagaactacagcggtccgacggtctacgtgcagaatgct
tcgcgtaccgtgggcgtggtggcggcgctactctccgacacccagcgtgatgactttgtc
gcccgtacccgcaaagagtacgaaaccgtgcgtattcagcacgcccgcaaaaaaccgcgc
acgccgccggtcacgctggaagcggcgcgcgataatgatctggcatttgattgggaacgc
tacaccccgccggtagcccaccgtctgggcgtgcaggaggtggaagccagcatcgaaacg
ctgcgcaactacatcgactggacgccgttctttatgacctggtcgctggccggcaaatac
ccgcgcattctggaagatgaggtggtgggcgttgaggcgcagcgtctgtttaaagacgcc
aatgatatgctggataaactgagcgccgagaaactgttgaatccgcgtggcgtggtgggc
ctgttcccggcgaaccgtgtgggtgacgacatcgaaatctatcgcgacgaaacccgtact
catgttctgacggtcagccaccacctgcgccagcagaccgagaaagttggttttgctaac
tactgtctggcggattttgtcgcgccgaaactgagcggcaaagcggactacatcggtgct
ttcgcggtgaccggcggtctgaaggaggatgcgctggcggacgccttcgaagcgcaacac
gacgactataacaagatcatggtgaaagcgattgccgaccgtctggcggaagcgtttgcc
gagtatctgcatgagcgtgtacgtaaggtttactggggatatgcgccgaacgagagcctg
agtaacgacgaattaatccgcgaaaactaccaggggattcgcccggcgccgggttatcct
gcctgcccggaacataccgaaaaaggcactatctggcagctactggatgtcgaaaaacac
accgggatgaagctcaccgaatctttcgccatgtggcctggcgcgtcggtctccggctgg
tacttcagccatcctgagagcaaatacttcgcggtagcgcagatccaacgcgatcaggtg
acagattatgctttccgtaaaggaatgagcgttgaggacgttgagcggtggctcgcgccg
aacctgggttacgatgcggactga

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