KEGG   Staphylococcus aureus subsp. aureus LGA251 (MRSA): SARLGA251_03190
Entry
SARLGA251_03190   CDS       T02085                                 
Name
(GenBank) methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
suf  Staphylococcus aureus subsp. aureus LGA251 (MRSA)
Pathway
suf00270  Cysteine and methionine metabolism
suf00450  Selenocompound metabolism
suf00670  One carbon pool by folate
suf01100  Metabolic pathways
suf01110  Biosynthesis of secondary metabolites
suf01120  Microbial metabolism in diverse environments
suf01230  Biosynthesis of amino acids
Module
suf_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:suf00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    SARLGA251_03190
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    SARLGA251_03190
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SARLGA251_03190
Enzymes [BR:suf01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     SARLGA251_03190
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     SARLGA251_03190
SSDB
Motif
Pfam: S-methyl_trans MTHFR DUF6506
Other DBs
NCBI-ProteinID: CCC87088
LinkDB
Position
complement(378783..380624)
AA seq 613 aa
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPKKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
NT seq 1842 nt   +upstreamnt  +downstreamnt
atgagtcaattcctcacacaattgaaagataatgttttagtagctgatggcgctattgga
accattttatactctgaagggttagacacctgcccagaagcatataatcttagccatcca
gataaagttgaacgcatccatcgttcatatatcgaagctggtgctgatgtcattcaaacc
aatacttatggtgcaaattttgaaaagttaaaacgattcggtcttgaagataaagttaaa
gctatacatcaagcagccgtacgcatcgcaaaaaaagcagcaaataaagatacgtatata
ttaggcacagttggtgggtttagaggtatcaaacaagaggatatcagcttacaaactatt
ctttatcatactgaaattcaaatagataccttaattgaagaaggcgttgacgcgctactt
ttcgaaacgtattacgacctagaagagctaacaaatgtcatttcacgaacgagaaagaaa
tacgacattccaatcattgctcaattaaccgcttcaaacacaaattacttagttaatggt
caggcaatcaatgaaggattaaaacaactcgttcaatgtggtgcaaacatcgtgggactc
aattgtcatcatggcccgcaccatatgcaagagtctttcacacatattgaattaccagag
cacgcatacttatcttgttatccaaatgccagcttattagatattgaaaatagtgaattt
aagtatagtgacaatgcacaatatttcggtcaagttgctcaaaatctaattcgcgaaggt
gttcgtttaattggtggttgctgtggtacaacgcctgagcacatcaaatttattaaagaa
tctattcagacacttaaacctgttaatgacaaaaaagtgattccgataccaaagaaagca
ctattcaatccatctcaaaataaagttagacaatcattaacatctaaggttcaagaacgt
ccaaccgttattatcgaattggatacaccgaaacatttagacacggatagattttttgaa
aatatcgctaaacttgataaagctaatgtagatgcggtaacactcgcagataattcattg
gcaactgtcagaattagcaacattgctgctgcaagcttaattaaacaatattacaatatt
gaaccactcgtacatattacatgtcgagaccgaaacttaatcggcttgcagtcccattta
cttggattatcgctcattggcgttaacgaaatattagccataactggtgatccttcaaaa
gttggtcacttaccaggtgcaaccaatgtctatgatgttaattctaaaggattaactgaa
ctcgctctaagatttaatcaaggtattaacactgacggtgatgcgctgaagaaacgtaca
cacttcaacatcgctggcgcctttaaccctaatgttcgtaaattagatggtgccgtaaaa
cgactagagaaaaagatagaaagcggaatgtcttattttataacacaacccgtgtacagc
aaagagaaaatcattgaaatttaccatgccactaagcacttgaacaaaccatttttcata
ggcattatgcctatcgcaagttacaaaaacgcactctttttgcataatgaagtgccagga
atcaagatgtcagatgaaattttacaacaatttgaagcagttaaagatgataaagccaaa
acacgagaactaagtcttaagctttcaaaggatttaatcgatactgttcatgaatatttt
aatggtttatacattatcacaccgtttcaaaatgtcgaagattcattagaacttgcagca
tactcaaaatctattactgctcacaaggaggcaatattatga

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