Sceloporus undulatus (fence lizard): 121922906
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Entry
121922906 CDS
T07740
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
sund
Sceloporus undulatus (fence lizard)
Pathway
sund00140
Steroid hormone biosynthesis
sund01100
Metabolic pathways
Module
sund_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
sund_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
sund_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
sund_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
sund00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
121922906
Enzymes [BR:
sund01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
121922906
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
121922906
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
NAD_binding_10
Polysacc_synt_2
GDP_Man_Dehyd
RmlD_sub_bind
NmrA
KR
Motif
Other DBs
NCBI-GeneID:
121922906
NCBI-ProteinID:
XP_042308787
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Position
2:225562961..225570038
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AA seq
377 aa
AA seq
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MALAGIRCLVTGAGGFLGRRIICQMLEEDQGPDEVRALDKAIGPETRRAFAKVKTKTLLT
VIEGDIRDVASLQTAVQGITVVIHTACIIDTLGIVDKHTLWDVNVRGTQLLLESCLRNSV
PYFIYTSSIEVTGPNSRGDPVYDGDEDTVYQSTQGFPYAENKKEAEKSVLEMDGLPLKDG
SSFVTCALRSMYIYGEGSLFLQRHLDQSIQNNNIFLRISQKEALVNPAYVGNVAWAHVQA
AKAMKDPEKVKRIRGQFYFISDDTPHVSYSDLNYELTKELGFGIQPKLAMPLMILYWYAL
LLEVVSFLLHPFVRYVPSINRHLVTLLNTPFSFSYRKAQRDFGYVPRYKWEEAKQQTSQW
IAKITPLRTAYLKNKNS
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atggccttggcagggattcggtgcctggtgaccggggccgggggcttcctgggccgaagg
atcatttgccagatgctggaggaggaccagggaccagatgaggtccgagccttggacaaa
gccattggcccagagacccgaagggcctttgcaaaagtgaagactaaaactctgctgaca
gtcattgaaggggacattcgggatgtggcatctcttcagacagctgtccaaggcatcact
gttgtcatccacacagcttgcatcattgacaccttaggaattgtcgacaaacacacactc
tgggatgtcaatgtccgaggtacacagctgctacttgagagttgcctccgcaacagtgtt
ccatattttatctacacaagtagcattgaagtgacaggtccaaacagcagaggtgatccc
gtctatgatggtgatgaagacacagtctatcagagcactcaaggctttccctatgctgaa
aacaagaaggaggcagagaagtctgtgctagagatggatggcctaccactgaaggatggc
agtagctttgtgacgtgtgctttgaggtccatgtatatctatggagaagggagccttttt
cttcagaggcatctcgaccagagcatccaaaacaataatatcttcctgaggatctctcag
aaggaggctcttgtaaatccagcttatgtggggaatgttgcttgggctcatgtccaagca
gctaaagccatgaaggatccagagaaagtcaagcgaatccgaggacaattctatttcatc
tcagatgataccccgcatgtaagctactcagatctcaattatgagctgaccaaggagttg
gggttcggcattcaacccaagttagcaatgcccttgatgatactctactggtatgctctg
ttactggaggtagtgagcttcttgctccatccttttgtgagatatgttcccagcatcaat
cgtcaccttgtgactttgctgaataccccattcagcttttcttacaggaaggcacagagg
gattttggctatgtgccacgctacaaatgggaagaagccaagcagcagacgagccagtgg
attgctaaaataactccactgaggacagcctacctgaaaaacaagaacagctaa
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