Streptomyces venezuelae: SVEN_1845
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Entry
SVEN_1845 CDS
T02274
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sve
Streptomyces venezuelae
Pathway
sve00010
Glycolysis / Gluconeogenesis
sve00020
Citrate cycle (TCA cycle)
sve00620
Pyruvate metabolism
sve00785
Lipoic acid metabolism
sve01100
Metabolic pathways
sve01110
Biosynthesis of secondary metabolites
sve01120
Microbial metabolism in diverse environments
sve01200
Carbon metabolism
sve01210
2-Oxocarboxylic acid metabolism
Module
sve_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sve00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SVEN_1845
00020 Citrate cycle (TCA cycle)
SVEN_1845
00620 Pyruvate metabolism
SVEN_1845
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SVEN_1845
Enzymes [BR:
sve01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SVEN_1845
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
CCA55132
UniProt:
F2RJC2
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Position
2056844..2059549
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AA seq
901 aa
AA seq
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MTDPVGKIPSELDQLPDRDTEETAEWAASLDAVTKAAGPHRAAYLMRRTLQHAEGAGLAL
PKLLETDYVNTIPTSAEPTGAAFDGDEDMERRITAWNRWNAAAMVTRGSKYGVGGHIATF
ASAAWLYETGFNHFFKGKEADGSGDQLYIQGHAAPGIYARAFLDGRLNEAHLDNFRQESG
GNGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRGIKDVSASHVWAFLGD
GEMDEPESTAALALAAREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVV
KSLWGNAWDELFALDTTGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPALVAMAQL
LSDDKILECFHLSRGGHEPRKVYAAYKAAVEFKGAPTVILAQTVKGFTLGEGFASKNANH
QMKKLSNDEFKNMRDLLELPISDAQFADGQVPYGHPGADSPEVRYLQERRAALGGPAPAR
RTHAIAPLPAPAEKAFTAFDKGSGSQSMATTMAFVRLVKDLIRDKETGKRWVPIVPDEAR
TFGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAVNGQILNEGITEAGSMADFIAASTA
YSTHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGH
SPVIAATNPAALTYDPAFAYEVAAIVKEGLRRMYGEAAEGEDQNVFYYLTVYNEPMPQPA
KPAGIDEGIVKGLYRFNTAESAGLDLPANAARIQLLSSGTAIHWALEAQKLLAAEWGVGA
DVWSATSWTELRRDALEADAALLRGEEQVPYIRRALEGVESPVLAVSDYMRQVPDQIAQW
VEQDWSSLGADGFGLSDTRDAARRHFGVDAQSIVVAALAQLARRGEVPASAVKEARERYG
L
NT seq
2706 nt
NT seq
+upstream
nt +downstream
nt
atgaccgatcccgtaggcaagattccgagcgagctcgaccagctcccggaccgtgacacc
gaggagaccgccgagtgggcggcctccctggacgccgtcaccaaggccgccggcccccac
cgggccgcctacctgatgcgccgcacgctccagcacgccgagggcgcgggcctggccctc
cccaagctgctggagacggactacgtcaacaccatcccgacctccgccgagccgacgggc
gccgctttcgacggcgacgaggacatggagcgccggatcaccgcctggaaccgctggaac
gcggccgcgatggtcacccgcggctcgaagtacggcgtcggcggccacatcgccaccttc
gcgtcggccgcctggctgtacgagaccggcttcaaccacttcttcaagggcaaggaagcc
gacggttccggcgaccagctctacatccagggccacgccgcgcccggcatctacgcccgc
gcgttcctggacgggcgcctcaacgaggcccacctcgacaacttccggcaggagtccggc
ggcaacggcctgccctcctacccgcacccgcgccgcctcccctggctgtgggagttcccc
accgtctccatgggtctcggcccgctctccgcgatctaccaggcgcgcttcaaccgctac
ctgaccaaccgcggcatcaaggacgtctccgcctcgcacgtgtgggcgttcctcggtgac
ggcgagatggacgagcccgagtcgaccgcggccctcgcactggccgcccgcgaaggcctg
gacaacctgaccttcgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgcc
aacttcaagatcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtg
aagtcgctgtggggcaacgcctgggacgagctgttcgcgctcgacaccaccggcgccctc
gtccgccgcctccgcgaggtcccggacgcgcaggtccagacgtaccagacccgcgacgcc
gcctacatccgcgaggacttcttcggcaaggacccggcgctcgtcgcgatggcgcagctg
ctgtccgacgacaagatcctggagtgcttccacctctcgcgcggtggccacgagccgcgc
aaggtgtacgccgcgtacaaggccgccgtcgagttcaagggcgcgccgacggtcatcctc
gcgcagaccgtcaagggcttcaccctcggtgagggcttcgcgtcgaagaacgcgaaccac
cagatgaagaagctctcgaacgacgagttcaagaacatgcgtgaccttctcgaactgccc
atctcggacgcgcagttcgccgacggccaggtgccctacggccaccccggcgccgactcc
cccgaggtccgctacctccaggagcgccgcgcggcgctcggcggcccggccccggcccgc
cgcacccacgcgatcgccccgctgccggccccggccgagaaggccttcaccgccttcgac
aagggctccggctcgcagtcgatggccacgacgatggcgttcgtccgcctggtcaaggac
ctgatccgcgacaaggagaccggcaagcgctgggtcccgatcgtcccggacgaggcccgc
accttcggcatggagtcgctgttcccgtcgctcggcatctactcgccgaagggccagacg
tacgagccggtcgaccgcgaccagctgatgtactacaaggaggccgtcaacggccagatc
ctcaacgaggggatcaccgaggccggttcgatggccgacttcatcgccgcgtccaccgcg
tactccacgcacggcgaagcgatgatcccgttctacatcttctactcgatgttcggctgg
cagcggaccgccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtc
ggcgccaccgcgggccgtacgaccctgaccggtgagggcctccagcacgccgacggccac
tcgccggtgatcgcggcgaccaacccggccgccctgacgtacgacccggcgttcgcctac
gaggtcgcggccatcgtcaaggagggtctgcgccggatgtacggcgaggccgccgagggc
gaggaccagaacgtcttctactacctgacggtctacaacgagccgatgccccagcccgcc
aagccggccggcatcgacgagggcatcgtcaagggcctgtaccgcttcaacacggcggag
tccgcgggtctcgacctgccggccaacgccgcgcgcatccagctgctctcctccggcacc
gccatccactgggccctggaggcgcagaagctgctcgccgccgagtggggcgtgggcgcc
gacgtgtggtccgcgacctcctggacggagctgcggcgcgacgcgctggaggccgacgcg
gcgctgctgcgcggcgaggagcaggtgccgtacatccgccgggccctggagggcgtcgag
tccccggtcctcgcggtctccgactacatgcgccaggtcccggaccagatcgcgcagtgg
gtcgagcaggactggtcctcgctcggtgccgacggcttcggcctctcggacacgcgtgac
gcggcccgccgccacttcggtgtcgacgcccagtcgatcgtcgtcgcggccctcgcgcag
ctcgcccgccgcggcgaggtcccggcctcggccgtgaaggaggcgcgcgagcgctacggc
ctgtag
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