Streptomyces venezuelae: SVEN_4966
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Entry
SVEN_4966 CDS
T02274
Name
(GenBank) Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex or 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sve
Streptomyces venezuelae
Pathway
sve00020
Citrate cycle (TCA cycle)
sve00630
Glyoxylate and dicarboxylate metabolism
sve00785
Lipoic acid metabolism
sve01100
Metabolic pathways
sve01110
Biosynthesis of secondary metabolites
sve01120
Microbial metabolism in diverse environments
sve01200
Carbon metabolism
sve01210
2-Oxocarboxylic acid metabolism
Module
sve_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sve_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sve00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SVEN_4966
00630 Glyoxylate and dicarboxylate metabolism
SVEN_4966
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SVEN_4966
Enzymes [BR:
sve01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SVEN_4966
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SVEN_4966
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SVEN_4966
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SVEN_4966
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
CCA58252
UniProt:
F2R2X7
LinkDB
All DBs
Position
complement(5342642..5346442)
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AA seq
1266 aa
AA seq
DB search
MSSQSPSTPSSPTDQDGQGQNPATAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GASETPTAPAPTTQSAPAAQQAGPAQAAPAAPAAVPAPAAAPAAPAPAPVKPAAAPAPAA
AKPAAAAPAPAKAAPAAAPKTEAPAGPELITLRGPAAAVAKNMNASLEVPTATSVRAVPV
KLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEKDGKPTLVKPEH
VNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVKRARVGKLTMEDFTGVTV
SLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYD
HRVIQGAASGEFLRVVANFLLGEEGFYDEIFKALRIPYEPVRWLKDIDASHDDDVTKAAR
VFELIHSYRVRGHVMADTDPLEYKQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSMMKL
RDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRVERPHSRVEREEQLRILRRLNAAEAF
ETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGK
SYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLEAVDPVL
EGIVRAKQDVINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVIN
NQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQTFNKDVVI
DLICYRRRGHNEGDNPQFTNPQMYNLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQ
GQLEKVFAEVREATAAPATATVPDAKAAFPVGVTTAVSAEVVKRIAESQVTIPERITVHP
RLLPQMQRRAASIDDGTIDWGFGETLAIGSLLMEGTPVRLSGQDSRRGTFGQRHAVLVDQ
ETGEDYTPLLYLTDDQAHYNVYDSLLSEYAAMGFEYGYSLARPDSLVIWEAQFGDFVNGA
QTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDNMTVAMPTL
PSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKVEEFTTGGFRPVIGDATANPADV
RKVVFCAGKVYYDLEAERQKRGDTETAIIRLERLYPLPGAELQAEIAKYPNAAKYIWAQE
EPANQGAWPFIALNLIDHLDLAVGADIPAGERLRRISRPHSSSPAVGSAKRHQAEQQQLV
NEVFDA
NT seq
3801 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaccccgagctccccgaccgaccaagacgggcagggccag
aaccctgctaccgccttcggtgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaattcggtcgatcgtgcctggtgggacttcttcgccgactacaagccc
ggagcgtcggagaccccgaccgccccggcgcccaccacccagagcgcgcccgccgcgcag
caggcgggccccgcacaggccgcgcctgccgctccggccgccgttccggctcccgccgcc
gccccggccgctccggccccggcccccgtgaagcccgccgcggcccccgcgccggccgcc
gcgaagccggccgccgccgctccggccccggcgaaggccgctccggccgccgcgccgaag
accgaggcccccgccggccccgagctgatcacgctgcgcggccccgccgccgcggtcgcg
aagaacatgaacgcctccctggaggtgccgacggccacgtccgtccgcgccgtcccggtg
aagctgctcttcgacaaccggatcgtgatcaacaaccacctgaagcgcgcccggggcggg
aagatctccttcacgcacctgatcggctacgcgatggtgcaggcgatcaaggccatgccg
tcgatgaactactccttcgcggagaaggacggcaagccgaccctggtcaagccggagcac
gtgaacttcggtctcgcgatcgacctggtgaagcccaacggcgaccgccagctcgtcgtc
gcgggcatcaagaaggccgagacgctcaacttcttcgagttctggcaggcgtacgaggac
atcgtgaagcgggcccgcgtgggcaagctgacgatggaggacttcaccggcgtcacggtc
tccctgaccaaccccggcggcctcggcaccgtccactccgtgccgcgcctgatgcccgga
cagtcggtcatcatgggcgtcggctcgatggactacccggccgagttccagggcacctcc
caggacaccctgaacaagctgggcatctcgaaggtcatgaccctgacctcgacgtacgac
caccgggtcatccagggcgccgcctccggcgagttcctgcgcgtcgtcgccaacttcctc
ctcggcgaggagggcttctacgacgagatcttcaaggccctgcgcatcccctacgagccg
gtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcgcgc
gtcttcgagctcatccactcctaccgggtccgcggccacgtcatggccgacaccgacccg
ctggagtacaagcagcgcaagcaccccgacctggacatcaccgagcacggcctcaccctg
tgggacctggagcgggagttcgcggtcggcggcttcgccggcaagtcgatgatgaagctc
cgcgacatcctcggcgtgctccgcgactcgtactgccgcaccaccggcgtcgagttcatg
cacatccaggacccgaagcagcgcaagtggatccaggaccgcgtcgagcgcccgcactcc
cgcgtggagcgcgaggagcagctgcggatcctgcgccggctgaacgccgcggaggccttc
gagaccttcctgcagaccaagtacgtcggccagaagcgcttctccctggagggcggcgag
tccgtcatcccgctgctcgacgcggtcatcgactcggccgccgaatcgcgcctcgacgag
gtcgtcatcggcatggcccaccgcggccggctgaacgtcctggcgaacatcgtcggcaag
tcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggc
tccggcgacgtcaagtaccacctgggcgccgagggcaccttcaccggtctcgacggcgag
cagatcaaggtctccctggccgcgaacccctcgcacctggaggcggtcgacccggtcctg
gaaggcatcgtccgcgccaagcaggacgtcatcaacaagggcggcacggacttcaccgtc
ctgcccgtcgccctgcacggtgacgcggccttcgccggccagggcgtcgtcgccgagacg
ctgaacatgtcgcagctgcggggctaccgcaccggcggcacggtccacatcgtcatcaac
aaccaggtcggcttcaccgccgccccggagtcctcgcgttcctcgatgtacgcgaccgac
gtggcccgcatgatcgaggcgccgatcttccacgtgaacggcgacgacccggaggccgtg
gtccgcgtcgcgcggctcgccttcgagttccgccagacgttcaacaaggacgtcgtgatc
gacctcatctgctaccgccgccgcggtcacaacgagggcgacaacccgcagttcaccaac
ccgcagatgtacaacctgatcgacaagaagcgttcggtgcgcaagctgtacaccgagtcg
ctcatcggtcgcggcgacatcaccctcgaagaggcggagcaggcgctccaggacttccag
ggccagctggagaaggtgttcgccgaggtccgcgaggccaccgccgccccggcgacggcg
accgtgccggacgccaaggccgccttcccggtcggcgtcaccaccgcggtctccgccgag
gtcgtgaagcggatcgccgagtcgcaggtcaccatcccggagcggatcacggtccacccg
cgtctgctgccgcagatgcagcgccgtgccgcctccatcgacgacggcaccatcgactgg
ggcttcggcgagaccctcgccatcggctcgctgctgatggagggcaccccggtccggctg
tccggccaggactcccgccgcggcaccttcggccagcgtcacgcggtcctggtggaccag
gagaccggcgaggactacaccccgctgctctacctgaccgacgaccaggcccactacaac
gtctacgactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcgctg
gcccgcccggactccctggtcatctgggaggcccagttcggtgacttcgtcaacggcgcg
cagaccgtcgtcgacgagttcatctcctcggccgagcagaagtggggccagacctccggc
gtcacgctgctcctgccgcacggctacgagggccagggcccggaccactcgtccgcgcgc
ccggagcgcttcctccagatgtgcgcccaggacaacatgacggtcgccatgccgacgctg
ccgtcgaactacttccacctgctgcgctggcaggtccacaacccgcaccacaagccgctc
atcgtcttcaccccgaagtcgatgctgcgtctgaaggccgcggcgtccaaggtggaggag
ttcaccaccggcggcttccgcccggtgatcggtgacgcgacggcgaacccggccgacgtc
cgcaaggtcgtcttctgcgccggcaaggtctactacgacctggaggccgagcggcagaag
cgcggcgacacggagaccgcgatcatccgcctcgagcgcctgtacccgctgccgggtgcc
gagctccaggccgagatcgccaagtacccgaacgcggcgaagtacatctgggcgcaggag
gagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgaccacctcgac
ctggcggtcggcgcggacatcccggcgggcgagcgcctgcgccggatctcccgtccgcac
tcctcctccccggcggtcggctcggccaagcgccaccaggcggagcagcagcagctggtc
aacgaggtcttcgacgcctga
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