Streptomyces venezuelae: SVEN_5977
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Entry
SVEN_5977 CDS
T02274
Name
(GenBank) Polyketide beta-ketoacyl synthase
KO
K05551
minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
sve
Streptomyces venezuelae
Pathway
sve00253
Tetracycline biosynthesis
sve01056
Biosynthesis of type II polyketide backbone
sve01100
Metabolic pathways
sve01110
Biosynthesis of secondary metabolites
Module
sve_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
sve00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
SVEN_5977
00253 Tetracycline biosynthesis
SVEN_5977
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
sve01004
]
SVEN_5977
01008 Polyketide biosynthesis proteins [BR:
sve01008
]
SVEN_5977
Enzymes [BR:
sve01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
SVEN_5977
2.3.1.260 tetracycline polyketide synthase
SVEN_5977
Lipid biosynthesis proteins [BR:
sve01004
]
Polyketide synthase
Component type
SVEN_5977
Polyketide biosynthesis proteins [BR:
sve01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
SVEN_5977
Nonaketide PKS
SVEN_5977
Decaketide PKS
SVEN_5977
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
CCA59263
UniProt:
F2RC12
LinkDB
All DBs
Position
6506817..6507833
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AA seq
338 aa
AA seq
DB search
MTARRVVITGIEVLAPGGTGSKAFWNLLSEGRTATRGITFFDPTPFRSRVAAEIDFDPEA
HGLSPQEIRRMDRAAQFAVVAARGAVADSGIDLAAHDPYRVGVTVGSAVGATMGLDEEYR
VVSDGGRLDLVDHAYAVPHLYDYMVPSSFSAEVAWAVGAEGPNTVVSTGCTSGLDSVGYA
VELIREGSADVMIAGSSDAPISPITMACFDAIKATTNRYDDPAHASRPFDGTRNGFVLGE
GAAVXXXXXXXTTRTVSASPSAAPSAPPWASTRSTGSSATAAGSTSSTTPTRCRTSTTTW
CPAPSPPRSPGPSAPRAPTPWSPPAAPPASTPSATPWS
NT seq
1017 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgcgcgacgcgtcgtcatcaccggcatcgaggtcctcgcccccggtggcaccgga
tccaaggccttctggaacctgctcagcgagggccgcacggccacccggggcatcaccttc
ttcgacccgacgccgttccgctcccgggtcgccgccgagatcgacttcgacccggaggcc
cacggcctcagcccgcaggagatccgccgcatggaccgggccgcccagttcgcggtggtc
gccgcgcgcggcgcggtcgccgacagcggcatcgacctggccgcccacgacccgtaccgc
gtcggcgtcaccgtcggcagcgccgtcggcgccaccatgggcctcgacgaggagtaccgg
gtcgtcagcgacggcggccggctcgacctcgtcgaccacgcctacgcggtgccgcacctc
tacgactacatggtgcccagctccttctccgccgaggtcgcctgggccgtcggcgccgag
ggccccaacaccgtggtctccaccggctgcacctccggcctcgactccgtcggctacgcc
gtggagctgatccgcgagggctccgccgacgtcatgatcgccggttcctcggacgccccg
atctccccgatcacgatggcctgcttcgacgccatcaaggcgaccaccaaccggtacgac
gacccggcgcacgcctcccggcccttcgacggcacccgcaacggcttcgtgctcggcgag
ggcgcggccgtnnnnnnnnnnnnnnnnnnnnccacgacccgtaccgtgtcggcgtcaccg
tcggcagcgccgtcggcgccaccatgggcctcgacgaggagtaccgggtcgtcagcgacg
gcggccggctcgacctcgtcgaccacgcctacgcggtgccgcacctctacgactacatgg
tgcccagctccttctccgccgaggtcgcctgggccgtcggcgccgagggccccaacaccg
tggtctccaccggctgcacctccggcctcgactccgtcggctacgccgtggagctga
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