Streptomyces violascens: HWN34_08295
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Entry
HWN34_08295 CDS
T08842
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
svio
Streptomyces violascens
Pathway
svio00020
Citrate cycle (TCA cycle)
svio00630
Glyoxylate and dicarboxylate metabolism
svio00785
Lipoic acid metabolism
svio01100
Metabolic pathways
svio01110
Biosynthesis of secondary metabolites
svio01120
Microbial metabolism in diverse environments
svio01200
Carbon metabolism
svio01210
2-Oxocarboxylic acid metabolism
Module
svio_M00009
Citrate cycle (TCA cycle, Krebs cycle)
svio_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
svio00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
HWN34_08295
00630 Glyoxylate and dicarboxylate metabolism
HWN34_08295
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HWN34_08295
Enzymes [BR:
svio01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
HWN34_08295
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
HWN34_08295
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
HWN34_08295
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
HWN34_08295
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Trypco1
Motif
Other DBs
NCBI-ProteinID:
QLA56563
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All DBs
Position
1963479..1967258
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AA seq
1259 aa
AA seq
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MSPQSPSNSSVSTDQAGQGKSPAAAFGSNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GGGGTAPVETAAPSAATPVAPAKPAPAAKAPEAKPAAAPAKPAEQAPAAKAAPAKTAPAK
AAPAKPAAKAAEPAAPAEGPEFVTLRGPSAAVAKNMSASLELPTATSVRAVPVKLLFDNR
IVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNNSFAQKDGKPTLVKPEHINLGLAI
DLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDNKLTMDDFSGVTVSLTNPGG
IGTVHSVPRLMPGQSVILGVGAMEYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGA
ASGEFLRIVANLLLGENEFYDDIFKALRIPYEPVRWLKDIDASHDDDVTKAARVFELIHS
YRVRGHVMADTDPLEYHQRKHPDLDINEHGLTLWDLERTFAVGGFAGKSMMKLRDILGVL
RDSYCRTTGIEFMHIQDPKQRKWIQDRVERGPGKPEREEQLRILRRLNSAEAFETFLQTK
YVGQKRFSLEGGESVIPLLDAVLDSAAEARLDEVVVGMAHRGRLNVLANIVGKSYAQIFR
EFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLTANPSHLEAVDPVMEGVVRAK
QDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTA
APESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVGRLAFEFRQAFNKDVVIDLICYRR
RGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVF
TEVREATSHPVEHEPEGPEAEFPVTVNTAVSPEVVKRIAESQVNIPERVTVHPRLLPQLQ
RRAAMVEDGTIDWGMGETLAIGSLLMEGTPVRLSGQDSRRGTFGQRHAVLIDRETGDDYT
PLLYLSDNQARYNIYDSLLSEYAAMGFEYGYSLARPESLVLWEAQFGDFVNGAQTVVDEF
ISSAEQKWSQHSGVTLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTLPSNYFHL
LRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGGFRPVIGDDSVDASQVRKVVLCA
GKVYYDLEAERQKRGVTDTAIIRVERLYPLPGAELQAEIAKYPNAEKFLWAQEEPANQGF
WPFIALNLIDHLDLGVGADLPAAERLRRISRPHSSSPAVGSAKRHQAEQAQLVAEVFDA
NT seq
3780 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaattcgagcgtctcgaccgaccaagcggggcagggcaag
agtcctgccgccgcgttcgggtcgaacgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactacaagccc
ggcgggggtggcacggctcccgtggagaccgcggccccctcggccgcgaccccggtggcg
ccggccaagcccgctccggcggccaaggcccccgaggcgaagccggctgccgcgccggcc
aagcccgccgagcaggcgccggccgccaaggccgcccccgcgaagacggcccccgccaag
gccgctccggccaagcccgccgcgaaggccgccgagcctgccgcgcccgcggaaggcccg
gagttcgtcacgctgcgtggcccctcggccgcggtcgcgaagaacatgagcgcctcgctg
gagctgcccacggccacgtccgtgcgcgcggtgccggtcaagctcctcttcgacaaccgc
atcgtcatcaacaaccacctgaagcgcgcccggggcgggaagatctccttcacgcacctg
atcggctacgccatggtgcaggccatcaaggccatgccgtcgatgaacaactccttcgcg
cagaaggacggcaagccgacgctggtcaagcccgagcacatcaacctcgggctcgccatc
gacctggtcaagcccaacggcgaccgccagctcgtcgtcgcggccatcaagaaggccgag
accctcaacttcttcgagttctggcaggcgtacgaggacatcgtccgccgggcccgggac
aacaagctgacgatggacgacttctcgggcgtcaccgtctcgctgaccaaccccggcggc
atcggcaccgtccactcggtgccgcgtctgatgcccggccagtcggtgatcctcggcgtg
ggcgcgatggagtacccggcggagttccagggcacctcgcaggacaccctgaacaagctc
ggcatctcgaaggtcatgaccctgacgtcgacctacgaccaccgggtcatccagggcgcc
gcctccggcgaattcctgcggatcgtcgccaacctgctgctcggcgagaacgagttctac
gacgacatcttcaaggcgctgcgcatcccctacgagccggtccgctggctcaaggacatc
gacgcctcgcacgacgacgacgtcaccaaggccgcccgcgtcttcgagctgatccactcc
taccgggtccgcggccacgtcatggccgacaccgacccgctcgagtaccaccagcgcaag
caccccgacctcgacatcaacgagcacgggctcacgctgtgggacctggagcgcaccttc
gccgtcggcggcttcgccggcaagtcgatgatgaagctccgcgacatcctcggcgtcctg
cgcgactcgtactgccgcaccaccggcatcgagttcatgcacatccaggacccgaagcag
cgcaagtggatccaggaccgggtggagcgcggtccgggcaagcccgagcgcgaggagcag
ctgcgcatcctgcggcggctcaacagcgccgaggcgttcgagaccttcctgcagaccaag
tacgtcggccagaagcggttctcgctggagggcggcgagtccgtcatcccgctgctcgac
gcggtcctggactcggcggccgaggcgcggctggacgaggtcgtcgtcggcatggcccac
cgcggccgcctcaacgtcctcgccaacatcgtcggcaagtcgtacgcgcagatcttccgg
gagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtcaagtaccac
ctgggcgccgagggcaccttcaccggcctggacggcgagcagatcaaggtctcgctcacc
gccaacccctcccacctggaggcggtcgacccggtcatggagggcgtggtccgcgccaag
caggacatcatcaacaagggcggcacggacttcaccgtcctgcccgtcgccctccacggt
gacgcggccttcgcgggccagggcgtggtggccgagacgctcaacatgtcgcagctgcgc
ggctaccgcaccggcggcacggtccacatcgtcatcaacaaccaggtcggcttcaccgcc
gcgccggagtcctcgcgctcctcgatgtacgccaccgacgtggcccgcatgatcgaggcg
ccgatcttccacgtgaacggtgacgacccggaggccgtcgtccgcgtcggacggctcgcc
ttcgagttccgccaggcgttcaacaaggacgtcgtcatcgacctgatctgctaccgccgc
cgcggccacaacgagtcggacaacccggccttcacccagccgctgatgtacgacctgatc
gacaagaagcgctcggtgcgcaagctctacaccgagtcgctgatcggccggggcgacatc
accctcgaagaggcggagcaggcgctccaggacttccagggccagctggagaaggtcttc
accgaggtccgcgaggccacctcgcacccggtggagcacgagccggagggccccgaggcg
gagttcccggtcacggtcaacaccgcggtctccccggaggtcgtcaagcggatcgccgag
tcgcaggtcaacatccccgagcgggtcaccgtccacccccgtctgctgccgcagctccag
cgccgcgcggcgatggtcgaggacggcacgatcgactggggcatgggcgagaccctggcc
atcggctcgctgctgatggagggcaccccggtgcgcctctccggccaggactcgcgccgc
ggcaccttcggccagcgccacgcggtcctcatcgaccgggagaccggcgacgactacacg
ccgctgctgtacctctcggacaaccaggcccgctacaacatctacgactcgctgctctcc
gagtacgcggcgatgggcttcgagtacggctactcgctggcccgtccggagtcgctggtg
ctgtgggaggcccagttcggtgacttcgtcaacggcgcgcagaccgtcgtcgacgagttc
atctcctcggccgagcagaagtggagccagcactccggtgtgacgctgctgctgccgcac
ggctacgagggccagggcccggaccactcctcggcccgcccggagcggttcctccagctc
tgcgcgcagaacaacatgacggtcgccatgccgaccctcccgtcgaactacttccacctc
ctgcggtggcaggtgcacaacccgcaccacaagccgctggtggtcttcacgccgaagtcg
atgctgcgcctgaaggccgccgcgtcgaaggcggaggagttcacgacgggcggcttccgc
ccggtcatcggcgacgactcggtggacgcctcgcaggtccgcaaggtcgtcctctgcgcc
ggcaaggtctactacgacctggaggccgagcggcagaagcgcggcgtcacggacaccgcg
atcatccgcgtcgagcgcctgtacccgctgccgggtgccgagctccaggcggagatcgcc
aagtacccgaacgccgagaagttcctgtgggcccaggaggagccggcgaaccagggcttc
tggccgttcatcgcgctcaacctgatcgaccacctggacctgggtgtcggcgcggacctc
ccggcggccgagcggctgcggcgcatctcgcgtccgcactcctcgtccccggcggtcggt
tcggccaagcgccaccaggccgagcaggcccagctggtcgccgaggtcttcgacgcctga
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