KEGG   Streptomyces violascens: HWN34_26120
Entry
HWN34_26120       CDS       T08842                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
svio  Streptomyces violascens
Pathway
svio00270  Cysteine and methionine metabolism
svio00450  Selenocompound metabolism
svio00670  One carbon pool by folate
svio01100  Metabolic pathways
svio01110  Biosynthesis of secondary metabolites
svio01230  Biosynthesis of amino acids
svio04980  Cobalamin transport and metabolism
svio04981  Folate transport and metabolism
Module
svio_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:svio00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    HWN34_26120 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    HWN34_26120 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    HWN34_26120 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    HWN34_26120 (metH)
   04980 Cobalamin transport and metabolism
    HWN34_26120 (metH)
Enzymes [BR:svio01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     HWN34_26120 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: QLA59783
LinkDB
Position
5964499..5968023
AA seq 1174 aa
MASSPTHRTALSAAARADALREALATRVVVADGAMGTMLQAQDPTLDDFQQLEGCNEILN
LTRPDIVTSVHDAYFAVGVDCVETNTFGANHAALGEYDIPERVFELSEAGARVARESADR
FTVETGQQRWVLGSMGPGTKLPTLGHAPYTTLRDAYQRNAEGMIAGGADALLVETTQDLL
QTKASVIGARRALEATGANLPVIVSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCA
TGPAEMSEHLRHLARHSRVPISCMPNAGLPVLGKDGAHYPLTASELADAQEGFVREYGLS
LVGGCCGTTPEHLRQVVERVRGAVPGERDPRPEPGAASLYQTVPFRQDTSYLAIGERTNA
NGSKKFRTAMLEGRWDDCVEMAREQIREGAHLLDLCVDYVGRDGVADMTELAGRFATAST
LPLVLDSTEVDVLRAGLEKLGGRAVINSVNYEDGDGPDSRFAKVTALAQEHGAALMALTI
DEEGQARTTEHKVAVAERLIEDLTGNWGIHESDILIDTLTFTICTGQEESRRDGVHTIEA
IRELKRRHPDVQTTLGLSNISFGLNPAARIVLNSVFLDECVKAGLDSAIVHASKILPIAR
LEEEHVKVALDLIHDRRAEGYDPLQTFLELFEGVDTKSMKAGKAEELLALPLDERLKRRI
IDGEKNGLHEDLDEALTERPALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKDA
VAHLEPHMEKAEGDEEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSA
ILEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRGLASGYPVILGGAALTRAYVEQDL
HEIYEGEVRYARDAFEGLRLMDALIAVKRGVPGATLPELKQRRVRATASATVTEEREEGP
VRSETATDNPVPTPPFWGTRVAKGIPLKDYASWLDEGALFKGQWGLKQNRAGDGPSYEEL
VETEGRPRLRGWLDELHTRNLLEAAVIHGYFPCVSKGDDLIVLDDAGNERTRFSFPRQRR
GKRLCLADFFRPEESGETDVVGFQVVTVGSRIGEATAELFAANSYRDYLELHGLSVQLAE
ALAEYWHARVRAELGFGGEDPVDVEDMFALKYRGARFSLGYGACPNLEDRAKIADLLQPE
RIGVHLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3525 nt   +upstreamnt  +downstreamnt
atggcctcgtcgccgacccatcggaccgcactctccgccgccgcccgcgcggacgccctc
cgcgaagctctggccacccgggtggtggtcgcggacggggcgatgggcacgatgctccag
gcgcaggacccgaccctcgacgatttccagcagctcgaaggctgcaacgagatcctcaac
ctcacccgcccggacatcgtcacctcggtgcacgacgcgtacttcgcggtgggggtcgac
tgtgtggagaccaacaccttcggtgccaatcacgcggcgctgggggagtacgacattcct
gagcgggtcttcgagctttccgaggcgggtgcccgggtcgcgcgggagagcgccgaccgt
ttcaccgtcgagacggggcagcagcggtgggtgctcggctcgatgggcccggggaccaag
ctgccgaccctgggccacgccccgtacaccacgctgcgtgatgcctatcagcggaacgcg
gaggggatgatcgcgggcggcgcggacgcgttgctggtggagacgacccaggacctgctc
cagaccaaggcgtcggtgatcggtgcccgccgcgccctggaggcgaccggcgccaatctg
ccggtcatcgtctcggtcaccgtcgagaccaccggcacgatgctgctgggctcggagatc
ggtgcggcgctcaccgccctggagccgctgggcatcgacatgatcggcctgaactgcgcg
accggtcccgccgagatgagcgagcacctgcgccacctcgcccgccactcgcgcgtcccg
atctcctgcatgcccaacgccggtctgcccgttctcggcaaggacggcgcgcactacccg
ctgaccgcctccgagctggccgacgcccaggagggcttcgtccgcgagtacggtctctcc
ctggtcggtggctgctgcggcaccacccccgagcacctgcgccaggtcgtggagcgcgtg
cggggtgccgtccccggcgagcgggacccgcgccccgagccgggcgccgcctcgctctac
cagacggtgccgttccggcaggacacctcgtacctggcgatcggtgagcggaccaacgcc
aacggctcgaagaagttccgcaccgcgatgctggagggccgctgggacgactgcgtggag
atggcgcgtgagcagatccgtgagggcgctcacctgctcgacctctgcgtcgactacgtg
ggccgcgacggtgtcgccgacatgacggagctggccgggcggttcgccaccgcctcgacc
ctgccgctggtcctggactccaccgaggtcgacgtgctccgtgccgggctggagaagctg
ggcgggcgcgctgtcatcaactccgtcaactacgaggacggggacggccccgactcccgg
ttcgccaaggtgaccgcgctggcccaggagcacggtgcggccctgatggcgctgaccatc
gacgaggagggccaggcccgcaccaccgagcacaaggtggctgtggccgagcggctgatc
gaggacctgaccggcaactggggcatccacgagtcggacatcctcatcgacaccctgacc
ttcacgatctgcaccggtcaggaggagtcccgcagggacggcgtgcacaccatcgaggcg
atccgcgagctgaagcgccgccaccccgacgtgcagaccacgctgggtctgtccaacatc
tccttcggcctcaaccccgcggcccgcatcgtgctgaactccgtcttcctggacgagtgc
gtcaaggcgggtctcgactcggcgatcgtgcacgcctccaagatcctgccgatcgcccgg
ctggaggaggagcacgtcaaggtcgctctcgacctcatccacgaccgccgcgccgagggg
tacgacccgctccagaccttcctggagctcttcgagggcgtcgacaccaagtcgatgaag
gccggcaaggccgaggaactcctcgccctgccgctggacgagcggctcaagcgccgcatc
atcgacggtgagaagaacggcctgcacgaggacctggacgaggcgctgaccgagcggccc
gccctggacatcgtcaacgacaccctgctggacggcatgaaggtggtcggcgagctgttc
ggctccggccagatgcagctgcccttcgtcctgcagtccgccgaggtcatgaaggacgcg
gtggcccacctggaaccccacatggagaaggccgagggcgacgaggagggcaagggcacc
atcgtgctcgccaccgtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatc
atcctctccaacaacggctacaacgtcgtcaacctcggcatcaagcagcccgtctccgcc
atcctggaggccgccgaggagcaccgcgccgacgtcatcggcatgtccggactcctcgtc
aagtccacggtgatcatgaaggagaacctggaggagctgaaccagcgcggcctggcctcc
ggctaccccgtcatcctcggcggcgccgccctcacccgcgcctacgtcgaacaggacctc
cacgagatctacgagggagaggtccgctacgcccgcgacgccttcgagggcctgcgcctg
atggacgccctcatcgccgtcaagcgcggcgtccccggcgccaccctccccgaactgaag
cagcgcagggtgcgggccaccgcctcagccacggtgaccgaggagcgcgaggagggcccg
gtccgctccgagaccgccaccgacaacccggtccccaccccgccgttctggggcacccgc
gtcgccaagggcatcccgctcaaggactacgcctcctggctcgacgagggcgccctcttc
aagggccagtggggcctgaagcagaaccgcgccggcgacggccccagctacgaggaactg
gtcgagaccgagggccgcccccggctgcgcggctggctggacgagctgcacaccaggaac
cttctcgaagccgccgtcatccacggctacttcccctgcgtcagcaagggcgacgacctc
atcgtgctggacgacgcgggcaacgagcggacccgcttcagcttcccccgccagcgccgg
ggcaagcggctctgcctcgccgacttcttccgccccgaggagtccggcgagaccgatgtg
gtcggcttccaggtcgtcaccgtcggctcccgcatcggcgaggccaccgccgagctgttc
gccgccaactcctaccgcgactacctcgaactccacggcctgtccgtgcagctcgccgag
gccctcgccgagtactggcacgcccgcgtccgcgccgagctgggcttcggcggggaggac
ccggtcgacgtcgaggacatgttcgccctgaagtaccgcggcgcccgcttctcactcggc
tacggcgcctgcccgaacctggaggaccgcgccaagatcgccgacctgctccagcccgag
cggatcggcgtgcacctctcggaggagttccagctccaccccgagcagtccaccgacgcc
atcgtcatccaccaccccgaggccaagtacttcaacgcgcgctga

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