Streptomyces violascens: HWN34_26120
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Entry
HWN34_26120 CDS
T08842
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
svio
Streptomyces violascens
Pathway
svio00270
Cysteine and methionine metabolism
svio00450
Selenocompound metabolism
svio00670
One carbon pool by folate
svio01100
Metabolic pathways
svio01110
Biosynthesis of secondary metabolites
svio01230
Biosynthesis of amino acids
svio04980
Cobalamin transport and metabolism
svio04981
Folate transport and metabolism
Module
svio_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
svio00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HWN34_26120 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
HWN34_26120 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
HWN34_26120 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
HWN34_26120 (metH)
04980 Cobalamin transport and metabolism
HWN34_26120 (metH)
Enzymes [BR:
svio01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
HWN34_26120 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tautomerase_2
Motif
Other DBs
NCBI-ProteinID:
QLA59783
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All DBs
Position
5964499..5968023
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AA seq
1174 aa
AA seq
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MASSPTHRTALSAAARADALREALATRVVVADGAMGTMLQAQDPTLDDFQQLEGCNEILN
LTRPDIVTSVHDAYFAVGVDCVETNTFGANHAALGEYDIPERVFELSEAGARVARESADR
FTVETGQQRWVLGSMGPGTKLPTLGHAPYTTLRDAYQRNAEGMIAGGADALLVETTQDLL
QTKASVIGARRALEATGANLPVIVSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCA
TGPAEMSEHLRHLARHSRVPISCMPNAGLPVLGKDGAHYPLTASELADAQEGFVREYGLS
LVGGCCGTTPEHLRQVVERVRGAVPGERDPRPEPGAASLYQTVPFRQDTSYLAIGERTNA
NGSKKFRTAMLEGRWDDCVEMAREQIREGAHLLDLCVDYVGRDGVADMTELAGRFATAST
LPLVLDSTEVDVLRAGLEKLGGRAVINSVNYEDGDGPDSRFAKVTALAQEHGAALMALTI
DEEGQARTTEHKVAVAERLIEDLTGNWGIHESDILIDTLTFTICTGQEESRRDGVHTIEA
IRELKRRHPDVQTTLGLSNISFGLNPAARIVLNSVFLDECVKAGLDSAIVHASKILPIAR
LEEEHVKVALDLIHDRRAEGYDPLQTFLELFEGVDTKSMKAGKAEELLALPLDERLKRRI
IDGEKNGLHEDLDEALTERPALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKDA
VAHLEPHMEKAEGDEEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSA
ILEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRGLASGYPVILGGAALTRAYVEQDL
HEIYEGEVRYARDAFEGLRLMDALIAVKRGVPGATLPELKQRRVRATASATVTEEREEGP
VRSETATDNPVPTPPFWGTRVAKGIPLKDYASWLDEGALFKGQWGLKQNRAGDGPSYEEL
VETEGRPRLRGWLDELHTRNLLEAAVIHGYFPCVSKGDDLIVLDDAGNERTRFSFPRQRR
GKRLCLADFFRPEESGETDVVGFQVVTVGSRIGEATAELFAANSYRDYLELHGLSVQLAE
ALAEYWHARVRAELGFGGEDPVDVEDMFALKYRGARFSLGYGACPNLEDRAKIADLLQPE
RIGVHLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3525 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgtcgccgacccatcggaccgcactctccgccgccgcccgcgcggacgccctc
cgcgaagctctggccacccgggtggtggtcgcggacggggcgatgggcacgatgctccag
gcgcaggacccgaccctcgacgatttccagcagctcgaaggctgcaacgagatcctcaac
ctcacccgcccggacatcgtcacctcggtgcacgacgcgtacttcgcggtgggggtcgac
tgtgtggagaccaacaccttcggtgccaatcacgcggcgctgggggagtacgacattcct
gagcgggtcttcgagctttccgaggcgggtgcccgggtcgcgcgggagagcgccgaccgt
ttcaccgtcgagacggggcagcagcggtgggtgctcggctcgatgggcccggggaccaag
ctgccgaccctgggccacgccccgtacaccacgctgcgtgatgcctatcagcggaacgcg
gaggggatgatcgcgggcggcgcggacgcgttgctggtggagacgacccaggacctgctc
cagaccaaggcgtcggtgatcggtgcccgccgcgccctggaggcgaccggcgccaatctg
ccggtcatcgtctcggtcaccgtcgagaccaccggcacgatgctgctgggctcggagatc
ggtgcggcgctcaccgccctggagccgctgggcatcgacatgatcggcctgaactgcgcg
accggtcccgccgagatgagcgagcacctgcgccacctcgcccgccactcgcgcgtcccg
atctcctgcatgcccaacgccggtctgcccgttctcggcaaggacggcgcgcactacccg
ctgaccgcctccgagctggccgacgcccaggagggcttcgtccgcgagtacggtctctcc
ctggtcggtggctgctgcggcaccacccccgagcacctgcgccaggtcgtggagcgcgtg
cggggtgccgtccccggcgagcgggacccgcgccccgagccgggcgccgcctcgctctac
cagacggtgccgttccggcaggacacctcgtacctggcgatcggtgagcggaccaacgcc
aacggctcgaagaagttccgcaccgcgatgctggagggccgctgggacgactgcgtggag
atggcgcgtgagcagatccgtgagggcgctcacctgctcgacctctgcgtcgactacgtg
ggccgcgacggtgtcgccgacatgacggagctggccgggcggttcgccaccgcctcgacc
ctgccgctggtcctggactccaccgaggtcgacgtgctccgtgccgggctggagaagctg
ggcgggcgcgctgtcatcaactccgtcaactacgaggacggggacggccccgactcccgg
ttcgccaaggtgaccgcgctggcccaggagcacggtgcggccctgatggcgctgaccatc
gacgaggagggccaggcccgcaccaccgagcacaaggtggctgtggccgagcggctgatc
gaggacctgaccggcaactggggcatccacgagtcggacatcctcatcgacaccctgacc
ttcacgatctgcaccggtcaggaggagtcccgcagggacggcgtgcacaccatcgaggcg
atccgcgagctgaagcgccgccaccccgacgtgcagaccacgctgggtctgtccaacatc
tccttcggcctcaaccccgcggcccgcatcgtgctgaactccgtcttcctggacgagtgc
gtcaaggcgggtctcgactcggcgatcgtgcacgcctccaagatcctgccgatcgcccgg
ctggaggaggagcacgtcaaggtcgctctcgacctcatccacgaccgccgcgccgagggg
tacgacccgctccagaccttcctggagctcttcgagggcgtcgacaccaagtcgatgaag
gccggcaaggccgaggaactcctcgccctgccgctggacgagcggctcaagcgccgcatc
atcgacggtgagaagaacggcctgcacgaggacctggacgaggcgctgaccgagcggccc
gccctggacatcgtcaacgacaccctgctggacggcatgaaggtggtcggcgagctgttc
ggctccggccagatgcagctgcccttcgtcctgcagtccgccgaggtcatgaaggacgcg
gtggcccacctggaaccccacatggagaaggccgagggcgacgaggagggcaagggcacc
atcgtgctcgccaccgtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatc
atcctctccaacaacggctacaacgtcgtcaacctcggcatcaagcagcccgtctccgcc
atcctggaggccgccgaggagcaccgcgccgacgtcatcggcatgtccggactcctcgtc
aagtccacggtgatcatgaaggagaacctggaggagctgaaccagcgcggcctggcctcc
ggctaccccgtcatcctcggcggcgccgccctcacccgcgcctacgtcgaacaggacctc
cacgagatctacgagggagaggtccgctacgcccgcgacgccttcgagggcctgcgcctg
atggacgccctcatcgccgtcaagcgcggcgtccccggcgccaccctccccgaactgaag
cagcgcagggtgcgggccaccgcctcagccacggtgaccgaggagcgcgaggagggcccg
gtccgctccgagaccgccaccgacaacccggtccccaccccgccgttctggggcacccgc
gtcgccaagggcatcccgctcaaggactacgcctcctggctcgacgagggcgccctcttc
aagggccagtggggcctgaagcagaaccgcgccggcgacggccccagctacgaggaactg
gtcgagaccgagggccgcccccggctgcgcggctggctggacgagctgcacaccaggaac
cttctcgaagccgccgtcatccacggctacttcccctgcgtcagcaagggcgacgacctc
atcgtgctggacgacgcgggcaacgagcggacccgcttcagcttcccccgccagcgccgg
ggcaagcggctctgcctcgccgacttcttccgccccgaggagtccggcgagaccgatgtg
gtcggcttccaggtcgtcaccgtcggctcccgcatcggcgaggccaccgccgagctgttc
gccgccaactcctaccgcgactacctcgaactccacggcctgtccgtgcagctcgccgag
gccctcgccgagtactggcacgcccgcgtccgcgccgagctgggcttcggcggggaggac
ccggtcgacgtcgaggacatgttcgccctgaagtaccgcggcgcccgcttctcactcggc
tacggcgcctgcccgaacctggaggaccgcgccaagatcgccgacctgctccagcccgag
cggatcggcgtgcacctctcggaggagttccagctccaccccgagcagtccaccgacgcc
atcgtcatccaccaccccgaggccaagtacttcaacgcgcgctga
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