Streptomyces violaceusniger: Strvi_7260
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Entry
Strvi_7260 CDS
T01602
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
svl
Streptomyces violaceusniger
Pathway
svl00010
Glycolysis / Gluconeogenesis
svl00020
Citrate cycle (TCA cycle)
svl00620
Pyruvate metabolism
svl00785
Lipoic acid metabolism
svl01100
Metabolic pathways
svl01110
Biosynthesis of secondary metabolites
svl01120
Microbial metabolism in diverse environments
svl01200
Carbon metabolism
svl01210
2-Oxocarboxylic acid metabolism
Module
svl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
svl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Strvi_7260
00020 Citrate cycle (TCA cycle)
Strvi_7260
00620 Pyruvate metabolism
Strvi_7260
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Strvi_7260
Enzymes [BR:
svl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Strvi_7260
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AEM86624
UniProt:
G2P8Q9
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Position
8300097..8302772
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AA seq
891 aa
AA seq
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MTDLARTRPSALDQLPDRDPEETAEWGASLDAVAQAAGSHRASYLMRRTLERAESTGLAL
PPLLESDYVNTIPTAAEPAFPGDEAMESRITAWNRWNAAAMVTRGSRDGLGGHIATFASA
AWLYETGFQHFFRGKEADSSGDQLYIQGHASPGIYARAFLDGRLTEHHLDHFRREAGGAG
LPSYPHPRRMPWLWEFPTVSMGLGPISAIYQARFNRYLAARGIKDTAGSHVWAFLGDGEM
DEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRAAGWNVVKSL
WGSAWDELFALDTSGALVRRLREVPDGQFQTYATRDAAYLREHFFGAEPELARLAQQLTD
AKLTECFHTSRAGHEPRKVYAAYRTAVEHKGAPTVVLAQTVKGWTLGPGFESRNANHQMK
KLTGKEFRAMRDLLELPIPDSKLGDGLVPYVHPGPDSPEVRYLQERRAALGGPAPARKVH
AVALPEPSAKPFEALAKGSGSQEIATTMAFVRLVKDLMRDKETGRRWVPIVPDEARTFGM
ESLFPTAGIYSPLGQTYDPVDRDQLLYYKEAQNGQILNEGITEAGSMADFTAAATSYATH
GEPMIPFYIFYSMFGWQRTADQMWALADQLGRGFLIGATAGRTTMTGEGLQHADGHSPLI
ASTNPAALAYDPAFAYEIGVIVRDGLRRMYGPEAEDVFYYLTVYNETKVQPPMPEGEGVE
EGILKGLYRYQEATAPAEDSPRIQLLASGTAIHWVLEAQKLLADDWGVAADVWSATSWSE
LRRDALSCDAAQLSGEDRVPYVTHALAGAPGPVLAVSDWMRAVPDQISQWVEQDWYSLGT
DGFGLSDTREAARRHFGVDAPAIVVAALSRLARQGAVRATAPKEAAERYGI
NT seq
2676 nt
NT seq
+upstream
nt +downstream
nt
atgaccgatctcgcacgcacgcggccgagtgcgctcgaccagcttccggaccgtgacccc
gaggagaccgccgaatggggcgcctccctggacgccgtcgcgcaggcggccgggtcccac
cgcgcctcgtacctcatgcgccgcaccctggagcgcgccgagagcaccgggctcgccctg
ccgcccctgctggagtcggactacgtcaacaccatcccgaccgccgccgagcccgcgttc
ccgggcgacgaggccatggagagccgcatcaccgcctggaaccggtggaacgcggcggcg
atggtcacccgcggcagccgtgacggcctcggcggccacatcgccaccttcgcctccgcc
gcctggctctacgagacgggctttcagcacttcttccgcggcaaggaggcggacagctcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacgggcggctgaccgagcaccacctggaccacttccgccgcgaggcgggcggcgcgggt
ctgccgtcctatccgcatccgcggcggatgccgtggctctgggagttccccaccgtctcg
atggggctcggcccgatctccgcgatctaccaggcccgcttcaaccgctatctggcggcg
cgcggcatcaaggacaccgcgggctcccacgtctgggccttcctcggcgacggcgagatg
gacgagccggagtcgacggccgcactggcgctggccgggcgcgagggcctggacaacctc
accttcgtcatcaactgcaatctgcagcggctcgacggcccggtgcgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcgcggcgggctggaacgtggtcaagtcgctg
tggggctccgcctgggacgagctgttcgcgctggacacctcgggtgcgctggtccgccgg
ctgcgcgaggtcccggacggccagttccagacgtacgcgacccgcgacgcggcctacctc
cgcgagcacttcttcggcgccgagccggagctggcccggctggcccagcagctcacggac
gccaagctcaccgagtgtttccacacctcgcgcgcgggccatgagccgcgcaaggtgtac
gcggcctaccgcacggccgtggagcacaagggcgccccgaccgtcgtgctcgcccagacc
gtcaagggctggacgctgggccccggcttcgagtcgcgcaacgccaaccaccagatgaag
aagctgaccggcaaggagttccgcgccatgcgggacctcctcgaactccccatcccggac
agcaagctgggcgacggcctcgtcccctacgtccaccccggccccgactcccccgaggtc
cgctacctccaggagcgccgcgcggccctcggcggccccgccccggcccgcaaggtccac
gcggtggccctgcccgagccgtccgcgaagccgttcgaggcgctcgccaagggctccggc
agccaggagatcgccaccaccatggccttcgtccggctggtcaaggacctgatgcgggac
aaggagaccgggcggcgctgggtgccgatcgtgccggacgaggcgcggaccttcggcatg
gagtcgctcttccccaccgccgggatctactccccgctcggccagacctacgacccggtc
gaccgcgatcagctcctgtactacaaggaagcgcagaacggtcagatcctcaacgagggg
atcaccgaggccggttcgatggccgacttcaccgccgccgcgacgtcgtacgcgacccac
ggcgagccgatgatccccttctacatcttctactcgatgttcggctggcagcgcaccgcc
gaccagatgtgggcgctcgccgaccagctcggccgcggcttcctcatcggcgccaccgcc
ggccgtacgacgatgaccggcgagggcctgcagcacgccgacggccactccccgctgatc
gcctccaccaacccggcggcgctcgcctacgacccggcgttcgcgtacgagatcggcgtg
atcgtacgggacggtctgcggcggatgtacggccccgaggccgaggacgtcttctactac
ctgaccgtctacaacgagaccaaggtccagccgccgatgcctgagggcgaaggcgtcgag
gagggcatcctcaagggcctgtaccgctaccaggaggccacggccccggccgaggactcc
ccccgtatccagctcctcgcctccggcaccgccatccactgggtgctggaggcccagaaa
ctcctcgccgacgactggggcgtggccgccgacgtgtggtccgccacctcctggagcgag
ctgcgccgtgacgccctgtcctgtgacgcggcgcagctcagtggcgaagaccgggtcccg
tacgtcacccatgccctggcaggcgcaccgggcccggtcctcgccgtcagcgactggatg
cgggccgtccccgaccagatcagccagtgggtcgagcaggactggtactcgctgggcacg
gacggcttcggcctctccgacacccgcgaggcggcccgccgccacttcggcgtggacgcc
ccggccatcgtggtggccgcgctgtcccggctggcccggcagggcgcggtacgggccacc
gcgcccaaggaggccgcggagcggtacggcatctga
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