Streptomyces xiamenensis: SXIM_11090
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Entry
SXIM_11090 CDS
T03904
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sxi
Streptomyces xiamenensis
Pathway
sxi00010
Glycolysis / Gluconeogenesis
sxi00020
Citrate cycle (TCA cycle)
sxi00620
Pyruvate metabolism
sxi00785
Lipoic acid metabolism
sxi01100
Metabolic pathways
sxi01110
Biosynthesis of secondary metabolites
sxi01120
Microbial metabolism in diverse environments
sxi01200
Carbon metabolism
sxi01210
2-Oxocarboxylic acid metabolism
Module
sxi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sxi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SXIM_11090
00020 Citrate cycle (TCA cycle)
SXIM_11090
00620 Pyruvate metabolism
SXIM_11090
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SXIM_11090
Enzymes [BR:
sxi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SXIM_11090
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
AKG42493
UniProt:
A0A0F7FR27
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Position
1211645..1214323
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AA seq
892 aa
AA seq
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MPDPVRLRLSALDQLPDRDPEETAEWGASLDAVAAAAGPHRAGQLVRRTVEHAQASGIDV
PSLLETDYINSIPTGAEPDFPGDEALEARVTAWNRWNAAAMVTRGARYGVGGHIATFASA
AWLYETGFQHFFRGKDAADAPGSGDQLFIQGHASPGIYARAFLDGRLTEAHLDNFRQESG
GAGLPSYPHPRRLPWLWEFPTVSMGIGPLSAIYQARFNRYLENRGIKDTSASHVWAFLGD
GEMDEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRAAGWNVI
KTLWGSAWDDLLRADTTGALVRRLREVPDAQFQTYATRDVAYIRDHFFGTDPALAQLGAS
LPDAKIAECFHTSRGGHEPRKVYAAYRAAVEFKGAPTVVLAQTVKGHTLGDGFQSRNANH
QMKKLTMEQFRTMRDLLELPIPDSELSGDLVPYAHPGPDSPEVRYLQERRAALGGPAPAR
RVHQVVLPEPSEKAFKALEKGSGSQEVATTMVIVRLVKDLMREKESGRRWVPIVPDEART
FGMESMFPSAGIYSPLGQTYESVDRDQLLHYKEAVNGQILNEGITEAGSMADFTAAATAY
ATHGEPMIPFYIFYSMFGWQRTGDQMWALGDQLGRGFIVGATAGRTTLTGEGLQHADGHS
PLIASTNPAALTYDPAFAYEVGVIVKDGLRRMYGPDAEDVFYYLTVYNEPKPQPAMPEGV
EEGILRGLYRFNEGQAPSAEAPRVQLMASGTAIHWVLEAQRLLSEQWGVAADVWSATSWS
ELRRDALSCDAAQLRGEDRVPYVTRALRGARGPVLAVSDWMRAVPDQIGQWVEQDYSSLG
TDGFGLSDTREAARRHFGVDPQSIVVAALDRLARSGEVKRETVLAAREAYGL
NT seq
2679 nt
NT seq
+upstream
nt +downstream
nt
atgcccgatcccgtacgccttcggctctccgcgctcgatcagctgccggatcgtgatccc
gaggagaccgccgagtggggcgcgagcctcgacgccgtggccgccgccgccggcccgcac
cgggccggccagctggtgcgccgtacggtggagcacgcccaggccagcgggatcgatgtg
ccctcgctgctggagacggattacatcaactccatccccaccggcgccgagcccgacttc
cccggtgacgaggccctggaggcccgcgtcaccgcctggaaccgttggaacgccgccgcg
atggtcacccggggcgcccggtacggggtgggcggccacatcgccaccttcgcctccgcc
gcctggctgtacgagaccggcttccagcacttcttccgcggcaaggacgcggcggacgcg
cccggctccggcgaccagctgttcatccagggccacgcctcccccggcatctacgcccgc
gccttcctcgacggccgcctcaccgaggcgcacctggacaacttccgccaggagtcgggc
ggcgccggcctgccctcctacccgcacccgcggcggctgccgtggctgtgggagttcccc
accgtctccatgggcataggcccgctgtcggcgatctaccaggcgcggttcaaccgctac
ctggagaaccgcggcatcaaggacacctccgcctcgcacgtgtgggcgttcctgggcgac
ggcgagatggacgagcccgagtcgaccgccgcgctggcgctggccgggcgtgagggtctg
gacaacctcaccttcgtcatcaactgcaacctccagcggctcgacggcccggtgcgcgcg
aacttcaagatcgtgcaggagctggaggcccagttccgggcggccggctggaacgtcatc
aagaccctgtggggctccgcctgggacgacctgctgcgggccgacaccaccggcgcgctg
gtacggcggctgcgggaggtcccggacgcgcagttccagacgtacgccacccgcgacgtc
gcctacatccgcgaccacttcttcggcaccgacccggcgctggcccagctgggtgcctcg
ctgccggacgcgaagatcgccgagtgcttccacacctcgcgcggtggccacgagccccgc
aaggtgtacgccgcgtaccgggcggccgtggagttcaagggcgccccgaccgtggtgctg
gcccagaccgtcaagggccacaccctgggcgacggcttccagtcgcgcaacgccaaccac
cagatgaagaagctgacgatggagcagttccgcaccatgcgggacctgctggagcttccc
atcccggacagcgagctctccggcgatctggtgccctacgcgcaccccggccccgactcc
cccgaggtgcgctacctccaggagcggcgcgcggccctgggtggtccggcgccggcccgc
cgggtgcaccaggtggtgctgccggagccgtccgagaaggcgttcaaggcgctggagaag
ggctcgggctcgcaggaggtcgccaccaccatggtgatcgtccggctggtcaaggacctg
atgcgggagaaggagtcggggcggcgctgggtgccgatcgtccccgacgaggcccgtacc
ttcggcatggagtcgatgttcccgtccgccgggatctactcgccgctgggccagacctac
gagtcggtcgaccgcgaccagctgctgcactacaaggaagccgtcaacggccagatcctg
aacgaggggatcaccgaggccggttcgatggccgacttcacggcggcggccacggcgtac
gccacgcacggcgagccgatgatcccgttctacatcttctactcgatgttcggctggcag
cgcaccggcgaccagatgtgggcgctgggcgaccagctgggccgcggcttcatcgtgggc
gccacggccggccgcaccacgctgaccggtgagggcctccagcacgcggacggtcactcg
ccgctgatcgcctccaccaacccggcggcgctgacgtacgacccggcgttcgcgtacgag
gtgggcgtcatcgtcaaggacggcctgcgccggatgtacggcccggacgccgaggacgtc
ttctactacctgacggtctacaacgagccgaagccgcagcccgccatgcccgagggcgtg
gaggagggcattctgcgcggcctgtaccgcttcaacgaggggcaggccccctcggcggag
gcgccgcgggttcagctgatggcgtcgggtacggccatccactgggtgctcgaggcccag
cgacttctgtccgagcagtggggtgtggccgccgacgtgtggtccgccacctcctggagc
gagctgcgccgtgacgccctgtcctgtgacgcggcgcagcttcgaggggaagaccgggtc
ccgtacgtgacgcgtgcgctgcggggcgcgcggggcccggtcctcgccgtgagcgactgg
atgcgggcggtgcccgaccagatcggtcagtgggtcgagcaggactactcctcgctcggc
acggacggcttcggcctctccgacacccgtgaggcggcccgccggcacttcggcgtggac
ccgcagtcgatcgtggtggcggcgctggaccggctggcccggtccggtgaggtcaagcgc
gagacggtgctggcggcgcgcgaggcctacggcctgtaa
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