Streptomyces xanthii: IAG42_05315
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Entry
IAG42_05315 CDS
T07861
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
sxn
Streptomyces xanthii
Pathway
sxn00909
Sesquiterpenoid and triterpenoid biosynthesis
sxn01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
sxn00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
IAG42_05315 (shc)
Enzymes [BR:
sxn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
IAG42_05315 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
IAG42_05315 (shc)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Ulvan_lyase_N
Motif
Other DBs
NCBI-ProteinID:
QNS03099
UniProt:
A0A7H1B2Z4
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All DBs
Position
complement(1109238..1111244)
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AA seq
668 aa
AA seq
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MTATTDGSTGAPAPEATAATTAPAGATPDAAGARAAAGRAIQRATEFLLARQDERGWWKG
DLDTNVTMDAEDLLLRQFLGIRDRAVTEAAALFIRGEQREDGAWATFYGGPGDLSATVEA
YVALRLAGDEPEDPHMARASAWVRERGGIAASRVFTRIWLALFGWWKWDDLPELPPELIY
FPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPRNPNPRRPLAPVAS
WDGAFQRLDQLMHGYRKVALKPLRKAAMNTAARWIIERQENDGCWGGIQPPAVYSVIALH
LLGYDLDHPVLKAGLESLDRFAVWREDGARMIEACQSPVWDTCLATIALADAGLPADHPA
LVKAAGWMLDEQIDRPGDWSVRRPRLEPGGWAFEFHNDNYPDIDDTAEVVLALRRVNHPD
RPRLEKAIERGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHV
VEMLAVEGRTRDPRTRRGIQWLLAEQEANGAWFGRWGVNYVYGTGSVVPALVAAGLPKTH
PAIRRAVAWLESVQNEDGGWGEDLRSYRYEDWKGHGVSTASQTGWALLALLAAGERDSKA
AERGVAFLADTQTEDGTWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFTDR
AAAPAEGS
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggagcgcccgctcccgaggcgaccgcggccacc
accgcccccgcgggggcgacgcccgacgcggcaggggcacgggccgccgccggacgagcc
atacagcgtgccaccgagttcctgctcgcccggcaggacgagcggggctggtggaagggc
gacctcgacaccaacgtgacgatggacgccgaggacctgctgctccgccagttcctcggc
atccgcgaccgggccgtcacggaggccgccgccctcttcatccgcggcgagcagcgcgag
gacggcgcctgggccactttctacggcggccccggcgacctctccgccaccgtcgaggcc
tacgtcgccctgcgcctggccggcgacgagccggaagacccccacatggccagggcgtcc
gcgtgggtccgcgagcgcggcggcatcgcggccagccgcgtcttcacccgcatctggctg
gccctgttcggctggtggaagtgggacgacctgcccgaactcccgcccgagctcatctac
ttcccgaagtggatgccgctcaacatctacgacttcggctgctgggcccggcagaccatc
gtcccgctcaccatcgtgtccgcgaagcgtccggtgcggcccgcgcccttcccgctcgac
gagctgcacaccgacccccgcaacccgaacccccgcaggcccctggcgcccgtggccagt
tgggacggcgccttccagcgcctcgaccagctcatgcacggctaccggaaggtggccctc
aagccgctgcgcaaggccgcgatgaacacggcggcccgctggatcatcgagcggcaggag
aacgacggctgctggggcggcatccagcccccggccgtctactccgtcatcgccctgcac
ctgctcggctacgacctcgaccaccccgtcctcaaggccggcctggagtccctggaccgg
ttcgcggtgtggcgcgaggacggggcccggatgatcgaggcctgccagtcgcccgtatgg
gacacctgcctggcgaccatcgcgctcgccgacgcgggactgcccgccgaccatccggcg
ctcgtcaaggccgccggctggatgctggacgaacagatcgaccggcccggtgactggtcg
gtgcgaaggccccgactggagcccggcggctgggcgttcgagttccacaacgacaactac
cccgacatcgacgacaccgccgaggtcgtcctcgccctgcgccgggtgaaccaccccgac
cggccgcgcctggagaaggcgatcgagcgcggcgtgcgctggaacctgggcatgcagtcg
aagaacggcgcgtggggcgccttcgacgtcgacaacaccagcccgttccccaaccggctg
ccgttctgcgacttcggcgaggtcatcgacccgccgtccgccgacgtcaccgcgcacgtc
gtcgagatgctcgccgtcgaaggccgcacccgggacccgcgcacccgccgcggcatccag
tggctcctcgccgaacaggaggcgaacggcgcctggttcggccgctggggcgtcaactac
gtctacggcaccgggtccgtcgtgcccgccctcgtcgccgcgggcctgccgaagacgcac
cccgcgatccgccgcgcggtcgcctggctggagtcggtgcagaacgaggacggcggctgg
ggcgaggacctgcgttcgtaccgatacgaggactggaagggccacggcgtctccaccgcc
tcgcagaccggctgggcgctcctcgcgctcctcgcggccggcgagagggactccaaggcc
gccgagcgcggcgtcgcgttcctcgccgacacccagacggaggacggcacctgggacgag
ccgtacttcaccggcaccggattcccctgggacttctcgatcaactaccacctgtaccgg
caggtcttcccgctgaccgcgctcggccggtacgtccacggagaaccgttcacggaccgc
gccgcggccccggccgaggggagctga
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