Tachyglossus aculeatus (Australian echidna): 119937622
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Entry
119937622 CDS
T10703
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu04120
Ubiquitin mediated proteolysis
tacu04144
Endocytosis
tacu04330
Notch signaling pathway
tacu04668
TNF signaling pathway
tacu04932
Non-alcoholic fatty liver disease
Brite
Enzymes [BR:
tacu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
119937622 (ITCH)
Membrane trafficking [BR:
tacu04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
119937622 (ITCH)
Ubiquitin system [BR:
tacu04121
]
Ubiquitin ligases (E3)
HECT type E3
119937622 (ITCH)
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Ortholog
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Gene cluster
GFIT
Other DBs
NCBI-GeneID:
119937622
NCBI-ProteinID:
XP_038613107
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Position
15:27208335..27243700
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AA seq
879 aa
AA seq
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MTSGAARSGPAPGLTMKSQLQITVISAKLKENKKNWFGPSPYVEVSVDGQSKKTEKCSNT
SSPRWKQALTVIVTPVSKLSFRVWSHQTLKSDISLGSAVLDIQETLKSNNMKLDEVVVTL
QLAGDKEPAEIVGDLSVCLDGMHVDPEILINGSGIRPDSPTENDETRAKTEGRQSNDVPE
SREEAGSGESRRVNGNDSPSLPNGACKPSRPPRPSRPPPPTPRRPASVTSSPTAVPEAEM
SSAGSSPVGSASISSERGPEGAAAPAAGTPLPGPGAVTTPPAARPGQPGNPGSQQLSAAN
QGPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTT
TWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFTSTQNKEFDPLGPLPTGW
EKRTDSNGRLYFVNHNTRVTQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTT
TYIDPRTGKSALDNGPHIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQ
IMSFNPPDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQI
NPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEF
YNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHELKPNGSNILVTEANKEEYIRMVAEW
RLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAVYRHYTR
TSKQIGWFWQLVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENW
LPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2640 nt
NT seq
+upstream
nt +downstream
nt
atgactagcggtgcggcacgatcggggcccgcgcctggactgaccatgaaatcccaactg
cagatcacagtcatctcggcgaaactcaaagagaacaagaagaactggtttggaccgagc
ccctacgtggaagtgtcagtggacgggcagtccaagaagacggaaaagtgcagcaataca
agtagccccaggtggaagcaggcgctcaccgtgatcgtcactcctgtcagcaaactaagt
ttccgcgtctggagtcaccagacgttgaaatctgacatttcgctgggaagtgcggttctg
gacatccaggagacgttgaagtccaacaacatgaagctggacgaggtggtggtgaccctg
cagcttgccggtgacaaggagccagccgaaattgtgggagacttgtcggtgtgtctagat
gggatgcacgtcgatccggagatcctcatcaacggcagcgggatccgacctgacagtccc
accgagaacgatgaaaccagagccaagacggaaggcagacagagcaacgacgttcccgag
agccgtgaggaagcggggtccggtgaaagcaggagggtcaatggcaacgattctccctcc
ctcccgaatggcgcttgcaaaccctccaggcctccgaggccctcccgcccacccccgccc
accccgcggagaccggcctccgtcaccagctcgccgaccgccgtcccggaagccgagatg
tccagcgcgggctcgtcgccggtcgggagcgcgagcatatcgtcggagaggggtccggag
ggagccgccgcccctgccgccggcacccccttgcccggccccggggccgtgaccacacct
ccagccgcccggccggggcagcccggaaaccctggctcccagcagctcagcgccgccaac
caggggcctctgcccccagggtgggagcagagagtggaccagcacgggcgagtgtactac
gtggaccacgtggagaagaggaccacgtgggacaggccggagccccttcctccgggttgg
gagcggcgagtggacaatatggggcgcatctactacgtggaccacttcaccaggaccacc
acttggcagcggcccacactggagtccgtccgcaactacgagcagtggcagctgcagcgc
agtcagctccaaggggccatgcagcagttcaaccagagattcatctacgggaatcaggat
ttgtttacttcgacccagaataaagaatttgatcccttggggcccctgccaacaggatgg
gagaagaggacggacagcaacggcagactctacttcgtcaaccacaacacccgcgtcacg
cagtgggaggacccgcggagccaggggcagctgaatgagaagccgttgccggaaggctgg
gagatgcggttcacggtggatggcatcccctacttcgtggaccacaaccgcaggaccacg
acgtacatcgacccccggactgggaaatctgctctagacaacggtccccacattgcctac
gttcgagacttcaaggcgaaggtccagtatttccgattctggtgccagcaactggccatg
ccgcagcacatcaagatcaccgtgacgaggaaaacgctgtttgaggactcgtttcagcag
ataatgagcttcaacccgccggacctgcggagacgcttgtgggtcattttccctggagaa
gaaggcttggattacggaggtgtggccagagagtggttcttccttttgtcccacgaggtg
ctgaaccccatgtactgcctgtttgaatacgcaggcaaggacaactactgcctccagatc
aaccctgcctcctacatcaacccagatcacctcaaatacttccgattcatcggcaggttc
atcgccatggccctgttccacgggaagttcatcgacacgggcttctccttgccgttctac
aaacggatcctcaataagcccgtggggctcaaagacctggagtccatcgaccccgagttc
tacaactctctcatctgggtgaaggaaaacaacattgaagagtgcggcttggaaatgtac
ttctccgttgacaaggaaattctcggggagatcaaaagccacgagctgaagcccaatgga
agcaacatcctggtcacggaggcgaacaaggaggagtacatccgaatggttgccgaatgg
aggctgtctcggggcgtggaggaacagacccaggctttcttcgagggcttcaacgagatc
cttcctcagcagtacctgcagtactttgatgctaaggagctggaggtcctcctttgcggg
atgcaggagatcgacttgaacgattggcagagacacgccgtctaccgccactacaccagg
acgagcaagcagattggctggttctggcagctggtgaaagagatcgacaacgagaagagg
atgcggctgttgcagttcgtcacgggcacgtgcaggcttcctgtgggaggatttgccgac
ctgatggggagcaatggaccgcagaagttttgcattgaaaaagtgggaaaggaaaactgg
ctaccccgaagccacacctgtttcaacaggcttgacctgccgccctacaagagctacgag
cagctgaaggagaagctcctgttcgccatagaagagacagaagggttcgggcaggagtga
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