Tachyglossus aculeatus (Australian echidna): 119940442
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Entry
119940442 CDS
T10703
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu01522
Endocrine resistance
tacu04012
ErbB signaling pathway
tacu04062
Chemokine signaling pathway
tacu04148
Efferocytosis
tacu04151
PI3K-Akt signaling pathway
tacu04360
Axon guidance
tacu04370
VEGF signaling pathway
tacu04510
Focal adhesion
tacu04670
Leukocyte transendothelial migration
tacu04810
Regulation of actin cytoskeleton
tacu04935
Growth hormone synthesis, secretion and action
tacu05100
Bacterial invasion of epithelial cells
tacu05135
Yersinia infection
tacu05146
Amoebiasis
tacu05163
Human cytomegalovirus infection
tacu05165
Human papillomavirus infection
tacu05170
Human immunodeficiency virus 1 infection
tacu05200
Pathways in cancer
tacu05202
Transcriptional misregulation in cancer
tacu05205
Proteoglycans in cancer
tacu05208
Chemical carcinogenesis - reactive oxygen species
tacu05222
Small cell lung cancer
tacu05417
Lipid and atherosclerosis
tacu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
119940442 (PTK2)
04370 VEGF signaling pathway
119940442 (PTK2)
04151 PI3K-Akt signaling pathway
119940442 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
119940442 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
119940442 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
119940442 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
119940442 (PTK2)
04062 Chemokine signaling pathway
119940442 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
119940442 (PTK2)
09158 Development and regeneration
04360 Axon guidance
119940442 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119940442 (PTK2)
05202 Transcriptional misregulation in cancer
119940442 (PTK2)
05205 Proteoglycans in cancer
119940442 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
119940442 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
119940442 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
119940442 (PTK2)
05163 Human cytomegalovirus infection
119940442 (PTK2)
05165 Human papillomavirus infection
119940442 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
119940442 (PTK2)
05100 Bacterial invasion of epithelial cells
119940442 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
119940442 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
119940442 (PTK2)
05418 Fluid shear stress and atherosclerosis
119940442 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
119940442 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tacu01001
]
119940442 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
tacu01009
]
119940442 (PTK2)
Enzymes [BR:
tacu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119940442 (PTK2)
Protein kinases [BR:
tacu01001
]
Non-receptor tyrosine kinases
FAK family
119940442 (PTK2)
Protein phosphatases and associated proteins [BR:
tacu01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
119940442 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
Motif
Other DBs
NCBI-GeneID:
119940442
NCBI-ProteinID:
XP_038616628
LinkDB
All DBs
Position
18:399666..544426
Genome browser
AA seq
1142 aa
AA seq
DB search
MLWDRAGRRAPKPAGATWMEKSGCSPFPMCWAKEYDRYLASSKTMAAAYLDPNLNHTPSS
GVKTHLSSGMERSPGTMERVLKVFHYFENNSEPTSWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSSVRENYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKNDYMLDVADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLRRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGSNPTHLADFNQVQTIQYSNSEDKDRKGTL
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL
ANNEKQGARTHTVSVSGASHCQHKVKKARRFLPLVFCSHEPPPPDEISGDETDDYAEIID
EEDTYTMPSKSYGIDEARDYEIQRDRIDLGRCIGEGQFGDVHQGVYTTPENPAMAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
FSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSSDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGIKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKLQQEERMRMES
RRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQANHYQVSGYPGPQGVPA
LAGSIYPGPAPLLDQADTWNHRPQEIAMWQPNLEESAAMDMRGLGSMLPPTQLMEERLIR
QQQEMEEDQRWLEKEERFLKPDVRLSRGSMDREDGSLPGGPTGNQHIYQPVGKPEPAAPP
KKPPRPGAPSHLGSLASLSSPVDSYNEGVKPWRLQPQEISPPPTANLDRSNDRVYENVTG
LVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETMPILPASTHREIEMAQKLL
NSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMIGQAR
PH
NT seq
3429 nt
NT seq
+upstream
nt +downstream
nt
atgttgtgggaccgggcaggccggcgggccccgaaaccagcaggtgcaacctggatggag
aaaagcggctgcagccccttccccatgtgttgggccaaagaatatgaccgatacctagca
tcaagcaaaaccatggcagctgcataccttgatcccaacttgaaccacactccgagttcc
ggtgtgaagactcatctaagttcaggaatggagcgttcccccgggaccatggagcgagtg
ttaaaagtctttcactattttgaaaataacagcgagccgacgtcatgggccagcatcatc
cgacatggcgacgccactgatgtccggggcatcatacagaagatcgtggacagtcacaag
gtcaaacatgtggcctgttacggattccgccttagccacctgcgttcggaggaggttcac
tggctccatttggatatgggtgtttccagcgtgagagagaactatgaactagcccaccct
ccagaggaatggaaatatgaactgagaattcgctatttgcccaaaggatttctgaaccag
tttactgaggataaaccaactttgaatttcttctatcagcaggtgaaaaatgactacatg
ttggatgtagcagaccaagtggaccaagaaatcgctttgaagctaggttgcctggaaatt
cgacggtcctactgggagatgaggggcaatgcactggagaagaagtccaactacgaagtg
ctagagaaagatgttggtttaagaagattttttccaaagagtttactggactctgtcaag
gccaaaacactgcgaaagctgatccagcagacatttcggcagtttgccaaccttaataga
gaagaaagtattctgaaattttttgagattctctctccggtgtacagattcgataaagaa
tgcttcaagtgtgctctcggttcaagctggatcatatcagtggagctggcaattggtcca
gaagaaggaatcagttatcttacggataagggctcaaatccgacacacctggcggacttc
aatcaagtgcagacgattcagtactccaacagtgaagacaaagacagaaaaggaacgctg
caactcaaaatagcaggggcacctgagcctctgacagtgacagccccatccttaaccatt
gcggagaacatggctgacctgatagatggatattgccggctggtgaacggagcctcccag
tccttcatcatcagaccccagaaagaaggtgaaagggctttaccatcaataccaaagctg
gccaacaatgaaaagcaaggagcaaggacacatacagtttctgtgtcaggagccagtcac
tgtcagcataaagtaaagaaagctagacgctttctcccgttggtcttctgttcccacgaa
cctccacctccggatgaaattagtggggacgaaacggatgactatgcggagattatagat
gaagaagatacttacaccatgccatcaaaaagctatggaatagatgaagccagggattat
gagattcagcgggacagaatagatcttggacggtgcattggagaaggccagtttggagat
gtgcatcaaggcgtttacacgactccggagaatccagccatggcagttgcaattaaaaca
tgtaaaaactgtacctccgacagtgtgagagaaaaattcctccaagaagccctaacaatg
cgccagtttgaccaccctcatattgtgaagctcattggcgttataaccgagaacccggtc
tggatcatcatggagctgtgcacccttggggagctaaggtcatttttacaagtgaggaag
ttcagtttggacctggcttctttgattctgtatgcctaccagctcagtacagctcttgca
tatctggagagcaagaggtttgttcatcgggacattgctgctaggaatgtattggtgtcc
tcctctgactgtgtgaaattaggagactttggtttgtctcgatacatggaagacagtacg
tactacaaagcctccaaaggcaaattaccgataaagtggatggcgccggagtccatcaat
ttccggcgcttcacctcagccagtgacgtgtggatgtttggtgtgtgcatgtgggaaatt
ttgatgcacggcatcaagcctttccaaggagtgaagaacaatgacgtgattggccgaatt
gagaacggggaacggctcccgatgcctccgaactgccctcccaccctctacagcctaatg
acgaaatgttgggcctatgatcccagcaggcggcctcggtttacggagctcaaagcccag
ctcagtaccatcctggaggaagaaaagctgcagcaggaagagcggatgaggatggaatcg
cggagacaagtcaccgtgtcctgggattcgggaggctccgatgaagctccgcccaagccc
agcagacctggttaccccagtccaagatccagtgaagggttttatcctagtccccagcac
atggtccaagccaatcattaccaggtctctggctaccctgggcctcaaggggtgccagcc
ttggctggcagcatttacccaggacctgcacctctgttggaccaagcagatacctggaac
caccggcctcaggagatagccatgtggcaaccgaacctggaggagtcggcggccatggac
atgcggggcctcgggtccatgctgcccccaacacagctgatggaggagaggttgatccgg
cagcagcaagagatggaggaagatcaacgctggcttgagaaggaggagcggttcttgaag
cctgatgtgaggctctcacgaggcagcatggaccgagaggacggaagcctgccgggcggc
ccgacagggaatcaacatatatatcagcctgtgggtaaaccagaacccgcagccccgcct
aagaagcctcctcgccccggagcccctagtcacctgggaagccttgccagcctcagcagc
cctgtggacagttacaacgaaggagtgaagccatggaggctccagccccaagaaatcagc
cccccacctaccgcaaatttggaccgttccaacgacagggtgtatgagaacgtgacgggc
ctggtgaaagcagtgatagaaatgtctagtaagatccagccagcccctccagaggaatat
gtgccaatggtgaaggaagtcggcttggccctgagaacgttgctggcgacagtggatgag
accatgcccatcctcccagcgagcactcaccgagagatcgagatggcacagaagctgctt
aactcagatttgggggagctgatcaacaagatgaaactagcccagcagtacgtcatgacc
agcctccagcaggaatacaaaaaacaaatgctcacagctgctcacgcgctggccgtggat
gccaaaaacctgctcgatgtcattgatcaagcccgcttgaaaatgattgggcaggccagg
ccccattaa
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integrated database retrieval system
