Tachyglossus aculeatus (Australian echidna): 119940749
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Entry
119940749 CDS
T10703
Symbol
MTR
Name
(RefSeq) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu00270
Cysteine and methionine metabolism
tacu00450
Selenocompound metabolism
tacu00670
One carbon pool by folate
tacu01100
Metabolic pathways
tacu01230
Biosynthesis of amino acids
tacu01523
Antifolate resistance
tacu04980
Cobalamin transport and metabolism
tacu04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
119940749 (MTR)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
119940749 (MTR)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
119940749 (MTR)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
119940749 (MTR)
04980 Cobalamin transport and metabolism
119940749 (MTR)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
119940749 (MTR)
Enzymes [BR:
tacu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
119940749 (MTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
DUF2760
Motif
Other DBs
NCBI-GeneID:
119940749
NCBI-ProteinID:
XP_038616960
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All DBs
Position
19:1989222..2057930
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AA seq
1252 aa
AA seq
DB search
MKSSVKEELEAILRERIMVLDGGMGTLIQRRNLDEEAFRGRRFRDHPRPLRGNNDLLSLT
QPDVIYAIHQEYLLAGADIIETNTFSSTRVAQADYGLEHLAYQLNKSSAEVARRAANDVT
AQTGIKRFVAGALGPTNKTLSVSPSVERPDFRNITFDELVEAYREQARGLLDGGVDIMLV
ETVFDTANAKAALFALQELFEEEYPPKPIFISGTIVDKSGRTLSGQTGEAFVISVSHAQP
LCLGLNCALGAGEMRPFIEAIGKCTPAYVLCYPNAGLPNTFGDYDETPQVTARHLKSFAQ
SGLVNVVGGCCGTTPDHIRAIAAAVEACKPRVPPTSLPQGHMLLSGLEPFGVGPFTNFVN
IGERCNVAGSRKFANLIKAGNYEEALSVAKAQVEMGAQILDVNMDDGMLDGPRAMARFCK
LIASEPDIARVPLCIDSSNFAVIEAGLKCSQGKCIVNSISLKEGEADFLGKARRIRRYGA
AVVVMAFDEEGQATETAAKIQVCTRAYRLLVDGLAFNPNDIIFDPNILTIGTGMEEHNLY
AVNFIDATRAIKESLPGAKISGGLSNLSFAFRGMEAIREAMHGVFLYHAIRSGLDMGIVN
AGNLPVYDAIPRDLLRLCEDLIWNRDPDATEKLLHYAQTHAKGGKKAVQTDEWRDGPVEE
RLEYALVKGIEKYVVEDTEEARADRETYPRPLNVIEGPLMNGMKIVGDLFGAGKMFLPQV
IKSARVMKKAVGHLIPFMEKEREEKKAQTGSVEEEDPYQGTIVLATVKGDVHDIGKNIVG
VVLGCNNFRVIDLGVMTPCDKILKAALDNKADIIGLSGLITPSLDEMIFVAKEMERLEIK
IPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDDYFEEIVEEY
EDIRQDHYESLKERRYLSLAQARKNGFHVDWQAAPCPVKPRFLGTRVFDDYDLRRLVSYI
DWKPFFDVWQLRGKYPNRGFPKIFEDKTVGEEARKVYEDAQKMLKELIAQRKLRARGVVG
FWPAQSVQDDIHLFSEDAEPRTAEPIATFHGLRQQAEKDAASPDPYYCLSDFVAPLGSGV
PDYLGLFAVACFGVDALCRAFEQQGDDYSSILAKALGDRLAEAFAEELHERVRREFWGYR
PEERLAVGDLRRVRYEGIRPAPGYPSQPDHTEKITMWRLADVAETTGIVLTESLAMAPAS
AVSGLYFSSAQSRYFAVGKVYKDQVEDYARRKNLPVTEVERWLGPVLGYDVD
NT seq
3759 nt
NT seq
+upstream
nt +downstream
nt
atgaagtcgtcggtgaaagaggagctggaggccatcctgcgggagaggattatggtcctg
gacggtgggatggggacactgatccagcggcgaaacctggacgaggaggctttccgaggg
cggcgcttccgggaccacccgagacccctccggggcaacaacgacctcctcagcctcacc
cagcccgatgtcatctacgccatccaccaggaatacttactggccggggccgacataatc
gaaaccaacaccttcagcagcacgcgggtggcccaagcggactacggcctggagcatctg
gcctaccagctcaacaagagttcggcggaggtggcccggagggcggccaacgacgtcacg
gcccagacggggattaagaggttcgtggccggggccctgggccccaccaacaagaccctc
tccgtatccccctccgtggaaagacccgatttcaggaatatcacgttcgacgagctagtg
gaagcctaccgagagcaggcccgggggcttctggacggaggagtggacatcatgttggtc
gaaaccgtattcgacaccgccaacgccaaggccgccctgttcgccctccaggagctcttt
gaagaagagtatccgcccaagcccatcttcatctcgggcaccatcgtcgataagagcggc
cgcacgctgtcggggcagactggggaggcgttcgtcatcagcgtgtcccacgcccagccg
ctgtgcctcggcctcaactgcgccctgggggccggcgagatgcggcccttcatcgaagcc
atcgggaaatgcacgccggcctatgtcctctgctatcccaacgcaggtctccccaatacg
ttcggcgactacgatgaaacgccccaagtaacggcccgccacttgaagagctttgcccag
agcggtttagtcaacgtggtcgggggctgctgcgggaccaccccggatcacatcagggcg
atcgccgcggccgtggaagcctgcaaacctcgcgtccctccgacctcccttccccaagga
cacatgctgctgtcgggcctggagcccttcggcgtcggccccttcaccaacttcgtcaac
atcggcgagcgctgcaacgtggccggctcccggaagttcgccaacctcatcaaggccggc
aactatgaagaagctctgagcgtagccaaggcccaggtggagatgggcgcccagatcctg
gacgtcaacatggacgacggcatgttggacgggccgcgggccatggcccgattctgcaaa
ctgatcgcctccgagcccgacatcgccagggtcccgctctgcatcgactcctccaacttc
gccgtgatcgaagccggcctgaagtgctcccagggcaagtgcatcgtcaacagcatcagc
ctgaaggaaggggaggcggacttcctcgggaaagcccgccggatccggcggtacggggcc
gccgtggtggtcatggctttcgacgaagagggccaggccacggagacggccgccaaaatc
caggtgtgcaccagggcttaccgcctcctggtcgacggtctggccttcaaccccaacgac
atcatcttcgaccccaacatcctgaccatcggcaccggaatggaggagcacaacctgtac
gccgtcaacttcatcgacgccacccgggccataaaggaatcgctgcccggagccaagatc
agcgggggcctctcgaacctgtcgttcgcgttccgcggcatggaagccatccgcgaggcg
atgcacggcgtcttcctctaccacgccatccggtccgggctggacatggggatcgtgaac
gcgggcaacctgccggtgtacgacgccatcccccgggacctgctgcggctgtgcgaggac
ctcatctggaaccgggaccccgacgccaccgagaagctgctgcactacgcccagacccac
gccaaggggggcaagaaagccgtgcagacggacgagtggcgagacggccccgtggaggag
cgactggaatacgccctcgtcaagggcatcgagaagtacgtggtggaggacacggaggag
gccagggcggacagggagacctacccgcgcccgctgaacgtcatcgaggggcccctgatg
aacggcatgaaaatcgtcggcgatctcttcggagcagggaagatgttcctgccgcaggtc
atcaagtcagcccgggtcatgaagaaggcggtcggccacctcattccgttcatggaaaag
gagagagaggaaaagaaggctcagaccggcagcgtggaagaggaggacccctaccagggc
accatcgtgctggccaccgtcaagggcgacgtccacgatattggcaagaacatcgtcggc
gtggtgctgggctgcaacaacttcagggtcatcgacctgggggtcatgaccccgtgcgac
aagatcctcaaggccgcgctggacaacaaagcagatataatcggcctgtcgggactcatc
accccgtctttggacgagatgatctttgtggccaaggagatggagcgcttggagatcaag
attcctttgttgattggcggcgccaccacttcgcgaacccacacggccgtgaaaatcgct
cctcgctacagcgctccggtcatccacgtcctggacgcgtccaagagcgtggtggtgtgt
tcccagttgctggatgaaaacctgaaggacgactacttcgaggaaatcgttgaagagtac
gaagacatcaggcaagaccattatgagtctctcaaggaaaggcgatacctgagcctcgcc
caagccaggaagaatggcttccacgtcgactggcaggcagcgccttgcccagtcaagccg
cgcttcctcggcacgcgcgtcttcgacgactacgacctgcggcggctggtgagctacatc
gactggaagccgttcttcgacgtctggcagctccggggcaaatacccgaatcggggcttc
cccaagatcttcgaggacaagacagtgggtgaagaggccaggaaggtttacgaggacgcc
cagaagatgctcaaagagctgattgctcaacgaaaactccgcgccaggggcgtggttggc
ttctggccggcccagagcgtccaagacgacatccatctgttctcggaagatgcggagccc
cggaccgccgagcccatagccacgtttcacggcttaaggcagcaggcggagaaggatgcg
gcctcgcccgacccgtactactgcctgtccgacttcgtggccccgctgggctcgggcgtc
cccgactacctgggcctgtttgccgtggcctgcttcggcgtggacgcgctctgccgggcc
ttcgagcagcagggcgacgattacagcagcatcctggccaaggcgctgggcgaccggctg
gcggaggcgttcgcggaggagctccacgaacgggtccggcgggagttctggggctaccgc
ccggaggagcggctggccgtgggcgacctgcgccgcgtccgctacgagggcatccgcccg
gcccccggctacccgagccagcccgaccacacggagaagatcaccatgtggcggctggcg
gacgtcgccgagaccacggggatcgtgttaacggagtcgctcgccatggcgcctgcttcg
gcggtctctggcctctacttctccagcgctcagtcccgatatttcgccgtcggaaaggtt
tacaaggaccaggtcgaagactacgcccgaaggaaaaacctcccggtgaccgaagtggag
aggtggctcggccccgttctgggatacgacgtcgattag
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