Tachyglossus aculeatus (Australian echidna): 119941263
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Entry
119941263 CDS
T10703
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu04022
cGMP-PKG signaling pathway
tacu04068
FoxO signaling pathway
tacu04081
Hormone signaling
tacu04140
Autophagy - animal
tacu04152
AMPK signaling pathway
tacu04211
Longevity regulating pathway
tacu04213
Longevity regulating pathway - multiple species
tacu04910
Insulin signaling pathway
tacu04920
Adipocytokine signaling pathway
tacu04923
Regulation of lipolysis in adipocytes
tacu04930
Type II diabetes mellitus
tacu04931
Insulin resistance
tacu04932
Non-alcoholic fatty liver disease
tacu04935
Growth hormone synthesis, secretion and action
tacu05010
Alzheimer disease
tacu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
119941263 (IRS2)
04022 cGMP-PKG signaling pathway
119941263 (IRS2)
04152 AMPK signaling pathway
119941263 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
119941263 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
119941263 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
119941263 (IRS2)
04923 Regulation of lipolysis in adipocytes
119941263 (IRS2)
04920 Adipocytokine signaling pathway
119941263 (IRS2)
04935 Growth hormone synthesis, secretion and action
119941263 (IRS2)
09149 Aging
04211 Longevity regulating pathway
119941263 (IRS2)
04213 Longevity regulating pathway - multiple species
119941263 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
119941263 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
119941263 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
119941263 (IRS2)
04932 Non-alcoholic fatty liver disease
119941263 (IRS2)
04931 Insulin resistance
119941263 (IRS2)
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Motif
Pfam:
IRS
PH
PH_11
Motif
Other DBs
NCBI-GeneID:
119941263
NCBI-ProteinID:
XP_038617573
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Position
20:complement(12152319..12182090)
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AA seq
781 aa
AA seq
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MASPRASTTSPPPSPSNLNNNNNHPPPSSSPPSGVRKCGYLRKQKHGHKRFFVLLGGPAQ
PARLEYYDSEKKWRSKAPKRVISLASCLNVHKRADAKHKYLIALYTRDEYLAVAADDERE
QDGWYRALAELMTEGQEEARGLPGGGGASSLPAGFAPDDPHYREVWQVTVKPKGLGQARH
LTGVHRLCLSARTVGFVRLNRRLPSVTLQLMNIRRCGHSDSFFFIEVGRSAATGPGELWM
QADDAVVAQNIHETILDAMKALKEPAGFRPRSKSQSAATRPISVPAARPPRRARLEDPTA
AAAAAAARRARTASEGDGGKAKGLPPTAGSPASPSPSSVWAAHPCPPPTCSGSGSPSDPG
FSSLDEDAPRLPPPDWPGGYVRMEPARGPRPRTSSLSGPARPCPPPAPPSSASLDEHALS
RPPAGPPTGDCGPGGDASYVPMTPGSGARSPASVSAPRLIVRAAAAAAAVRGPGSPPGAG
GDYVRMFGGADGPALPNGDYLPMAPRRCGPSSSSSGSLPRPDRAPADGAQYVFMGWPADA
PSHPPRASPPTRPRPVRPTRLALGEPRTAGPYVNIDFGEAAASPPVDYVNLGFGSPDGGS
PSPPGGDPAPALGRLSLREGPGPPPAGPPRRPPTGPPDPHRGARVVRADPQGGRRRHSSE
TFSAPAAAGAPAFAHRPKRHNSASVDNVSPRKAPDGAAPAPFDGLDYLSRRLKANANAGP
DMHEISRKASFPSCSKEATFSPSIPTACSASCTEKALLFDPMPSTTVTVVGGGKSHLAGQ
I
NT seq
2346 nt
NT seq
+upstream
nt +downstream
nt
atggccagcccccgggcgtccactacgtcgccgccgccctctccctccaacctcaacaac
aacaacaaccacccgccgccgtcgtcgtcgccgccgtcgggggtgcgcaagtgcggctac
ctgcgcaagcagaagcacggccacaagcgtttcttcgtcctcctcgggggcccggcccag
ccggcccggctggagtactacgacagcgagaagaagtggcggagcaaggcgcccaaaagg
gtcatctccctggcctcctgcctcaacgtgcacaagagggccgacgccaagcacaagtac
ctcatcgccctgtacacgcgggacgagtacctggccgtggcggcggacgacgagcgggag
caggacggctggtaccgggccctggccgagctgatgacggaggggcaggaggaggcccgg
gggctccccggaggaggaggcgcgtcctcgctgccggccggcttcgcccccgacgacccg
cactaccgcgaggtgtggcaggtgaccgtgaagcccaaaggcctaggccaggcccgccac
ctgaccggcgtccaccggctgtgcctgtccgcccgcaccgtgggcttcgtccgcctcaac
cggcgcctgccgtcggtcaccctgcagctgatgaacatccgccggtgcggccactcggac
agcttcttcttcatcgaggtgggccgctcggccgccacgggccccggcgagctgtggatg
caggcggacgacgccgtggtggcccagaacatccacgagaccatcctggacgccatgaag
gccctcaaggagccggccggcttccggccccgcagcaagagccagtcggcggccacgcgg
cccatctccgtgccggccgcccggccgccccgtcgggcgcgcctcgaggacccgacggcg
gcggcggcggcggcggcggcccgcagggcgcggacggccagcgagggcgacggcgggaag
gccaagggcctccccccgacggcgggcagccccgccagcccctcgccgtcgagcgtgtgg
gcggcccacccgtgccccccgccgacctgcagcggcagcggctccccgagcgacccgggc
ttctcgtccctggacgaggacgccccccggttgccccccccggactggcccgggggctac
gtgcgcatggagcccgcccggggcccccggccgcggacctcgtccctgagcggcccggcc
cggccgtgcccgccgccggcgccgccctcctccgcctccctggacgagcacgccctgagc
cggccgccggcgggccccccgacgggggactgcggccccgggggcgacgcctcctacgtg
cccatgacccccggctccggggcccggagccccgccagcgtgtccgccccgaggctcatc
gtgcgcgccgccgccgccgccgccgccgtccgggggcccggctcgcccccgggagcgggg
ggcgactacgtgaggatgttcgggggggcggacggcccggcgctgcccaacggcgactac
ctccccatggccccccgccgctgcggcccctcgtcgtcctcctcgggctccctgccccgg
cccgaccgggcccccgccgacggggcccagtacgtcttcatggggtggccggcggacgcc
ccgtcgcacccgccgcgggcctcgccccccacgcggccccggcccgtccggccgacccgg
ctggccctgggggagccccgcaccgccggcccctacgtgaacatcgacttcggggaggcc
gccgcctccccgcccgtcgactacgtgaacctgggcttcggctcccccgacggcggctcg
ccctccccgccggggggagaccccgcgcccgccctcggccgcctgagcctccgggagggg
ccgggaccccccccggcggggcccccgcgccgccccccgacggggcccccggacccccac
cgcggcgccagggtggtccgcgccgacccccagggcggacgccgccgccacagctccgag
accttctcggcccccgccgccgccggagccccggccttcgcccaccgccccaagagacac
aactcggcctcggtggacaacgtgtccccccggaaggcccccgacggggcggccccggcc
cccttcgacggcctcgactatctgtcccggcgactcaaggccaacgccaacgccggccca
gatatgcatgaaatatccaggaaagcctccttcccttcatgctccaaggaggcgacgttt
tcaccatcgatacctactgcttgtagtgcttcctgcaccgaaaaggcactgctgtttgac
ccaatgccttcaaccaccgtgactgtagttggaggggggaagtctcatttggctggccag
atctga
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