Tachyglossus aculeatus (Australian echidna): 119950342
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Entry
119950342 CDS
T10703
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu04062
Chemokine signaling pathway
tacu04151
PI3K-Akt signaling pathway
tacu04217
Necroptosis
tacu04550
Signaling pathways regulating pluripotency of stem cells
tacu04630
JAK-STAT signaling pathway
tacu04658
Th1 and Th2 cell differentiation
tacu04659
Th17 cell differentiation
tacu05161
Hepatitis B
tacu05162
Measles
tacu05166
Human T-cell leukemia virus 1 infection
tacu05169
Epstein-Barr virus infection
tacu05200
Pathways in cancer
tacu05203
Viral carcinogenesis
tacu05223
Non-small cell lung cancer
tacu05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
119950342 (JAK3)
04151 PI3K-Akt signaling pathway
119950342 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
119950342 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
119950342 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
119950342 (JAK3)
04659 Th17 cell differentiation
119950342 (JAK3)
04062 Chemokine signaling pathway
119950342 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119950342 (JAK3)
05203 Viral carcinogenesis
119950342 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
119950342 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
119950342 (JAK3)
05161 Hepatitis B
119950342 (JAK3)
05162 Measles
119950342 (JAK3)
05169 Epstein-Barr virus infection
119950342 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
119950342 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tacu01001
]
119950342 (JAK3)
Enzymes [BR:
tacu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119950342 (JAK3)
Protein kinases [BR:
tacu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
119950342 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
FERM_C_FAK1
ABC1
SH2
FERM_M
RIO1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
119950342
NCBI-ProteinID:
XP_038628578
LinkDB
All DBs
Position
X1:122983965..123010903
Genome browser
AA seq
1114 aa
AA seq
DB search
MAPLGEDTPLIGGRSCSLSSSEVGGLQLLLYHHTNAPRSVPDSSWILTFSFGEYSAEDLC
IVAAKACGILPVCHSLFALATEDLKCWFPPNHIFTVDDTSVQVLVYRLRFFFPNWFGLER
CYRFGLRKDRASAILDFPVLDYLFAQARSDFVSGRMEFSLSLKEQEECLSLAVLDLTQLA
RERGQGPEEIFKSVSYKSCLPEKFRRQIQGLSFLTRKRIRKTVQQSLRQVAGCHADGRSL
KLKYLMDLERMDSAFPPETFPVKAPGTGHSEGARQLIHVSGENGISWNSSGNESSQHFCD
FPEITDISIKQVSRDGNPRETRLVTLTRTDNRTLEVEFPTLREALSFISLIDGYYRLTAD
AHHYFCKEVAPPQLLENIEDQCHGPITSEFAVNKLKVAGGIAGSYLLRRSPQDFDSFLLT
ICIQTPLGRDYKGCLIRKDPSGSFSLAGVGRPHSSLQELLAAAHNTGLRADGVALNLHTC
FPPRPKEKSNLIVVRRDCSQLPSSPSPQPRLHLSHMMFHTIQPESLQWHENLGHGSFTKI
YRGTRRDVADEETRETEVLLKVMDSTHQNCSESFLEAASVMSQVSHQHLVLLHGVCMAGD
SIMVQEFVRFGALDTHLKKHTPNITASWKLQVAKQLAYALNYLEDRRIVHGNVSAKKVLL
AREGDGASGSPPFIKLSDPGVSPAVLAKELLTDRIPWVAPECLWDPKSLSLEADKWSFGA
TVWEIFSGGTMPLSTLEPAEKLQFYKKQLQLPAPKWTELANLIGQCMDYSPPRRPSFRAV
VRELNSLITSDYELLSDLSPSELAVRDGFWPSTNLSACQDPTLFEERHLKYISLLGKGNF
GSVELCRYDPLGDNTGELVAVKRLQQSTAEQLRDFQREIQILKSLHSDFVVKYRGVCYSP
GRKSLRLVMEYLPNGCLRDYLQRNRQQLDSRLLLLYASQICKGMEYLGSQRYVHRDLANR
NILVESETHVKIGDFGLAKILPQDKEYYVVQEPGQSPIFWYAPESLSDNVFSRESDVWSF
GVVLYELYTYSEKNRSPSAEFLRMMGCDRTMPILCHLLELLKEGKRLPTPPGCPWEVHEL
MRSCWAHNPWERPSFSALGPQINALWDERSSGRG
NT seq
3345 nt
NT seq
+upstream
nt +downstream
nt
atggcgcccctgggagaagacacacccctgatcgggggtcgctcctgcagtctgtcatcc
agtgaggtgggggggctgcagctcctcctgtaccatcacaccaacgcccctcgctcggtg
cctgactcatcctggatcctgaccttctcctttggagaatactctgccgaagatctctgc
atcgtagctgccaaagcctgtgggatcctgcctgtgtgccacagtctctttgccctggcg
acagaagatctgaagtgctggtttccgcccaaccacatcttcacagtggatgacacgagt
gtgcaggtcctcgtctacaggctgaggttctttttcccaaactggtttggcctggagaga
tgttaccgcttcgggctgaggaaggatcgagccagcgccatcctagacttccccgtcctt
gactacctgtttgcccaggcccgcagtgactttgtcagtgggaggatggagttcagcttg
agtctgaaggagcaagaggagtgtctgagcttggctgtgctggacctgacccagctggcc
cgggagaggggccagggcccagaggagatcttcaagagtgtcagctataagtcctgcctc
ccagagaaattccgacggcagatccagggactcagcttcctgacccgaaagaggatccga
aagaccgtgcagcagtccctgcggcaggtggctgggtgccatgccgacggacgctcactg
aagctcaagtacctgatggatctggagcggatggactcagccttcccacccgagaccttc
cctgtgaaggcccctgggactgggcacagcgagggagcccgccagttaatccatgtgtct
ggggagaatggcatctcctggaactctagtggcaatgagagctctcagcatttctgcgac
tttcccgaaatcaccgacatcagcatcaagcaagtcagtcgggacggcaaccccagggag
acccggctcgtcactctcaccaggacagataacaggacactggaggtggagttccccact
ctgcgggaggccctgtccttcatctccctcattgatggctactaccgcctcacggctgat
gcccaccactatttctgcaaggaggttgccccaccgcagctcctggaaaacatagaggac
cagtgccacggccccatcacgtctgagtttgcagtgaacaagttgaaggtggcgggagga
atagcaggctcctacctgctgcgtcgcagcccccaggactttgacagcttcctgctcacc
atctgcatccagaccccgctgggccgggactacaagggctgtttgatccggaaggatcca
tcgggcagcttctcgctggccggggtgggccgtccccactcgagtctgcaagagctgctg
gctgcggcccacaacaccggcctgcgggctgatggagtggccctcaatctccacacctgc
ttccctccccggcccaaagagaagtccaatttgatcgtggtgcggagggactgcagtcaa
ctaccctcgtccccttcaccgcagccccggcttcacctcagtcacatgatgtttcacacc
atccagcccgagagtctgcagtggcacgaaaacctgggccacggctctttcaccaagatc
taccggggcacccggagggacgtggcagatgaggaaacgcgggagactgaagtgctgctc
aaagtcatggacagcacccaccaaaattgctctgagtccttcctggaagcggccagtgtg
atgagccaagtctcccaccagcacctggtgctgctccatggggtctgcatggcaggagat
agtatcatggtgcaggagtttgtccggttcggggcgctggacacgcacttgaagaagcac
acccccaacatcactgccagttggaagctgcaggtagccaagcagctggcctacgccctc
aactacctggaggacagacgcatcgtccacggcaacgtctctgccaagaaagtgctgctg
gcacgggaaggggatggggccagcgggagccccccattcatcaaactcagtgaccccggc
gtcagccctgcagtgctggccaaggagctgcttactgaccgcatcccgtgggtggcccct
gagtgcctgtgggatcccaagagcttgagcctggaagctgacaagtggagctttggtgca
acagtctgggagatcttcagtgggggcaccatgcccctgagcaccctggaacctgcagag
aaactccaattctacaagaagcagctccagctgcctgcgcccaagtggacggagctggcc
aacttgatcggacagtgcatggactactctcctccccgcaggccctccttccgtgcggtc
gtccgggaactcaacagcctcatcacctcagattatgaactcctctcggacctgtccccc
agtgaattggctgtccgagatgggttctggcccagcaccaacctgtctgcctgccaggac
cccacgctgtttgaggagcgccatctcaaatacatctccctgctgggcaagggcaacttt
gggagtgtggaattgtgtcgctatgaccccctgggggacaacaccggggagctggtggct
gtgaaacggctgcagcagagcacggcggagcagctcagagacttccaacgggagatccag
atcctcaagtctctccatagtgactttgtggtcaaataccggggtgtttgctacagccca
ggccggaagagcctgcgcctggtcatggagtacctgcccaatggttgcttgcgcgattac
ctgcagcgcaaccgccagcagctggattcccggctcctgctcctttacgcctcccagatc
tgcaaggggatggagtacctgggttctcagcgctacgtccacagggacctggccaacagg
aacatcctggtggagagtgagacgcatgttaagatcggggactttggcctggccaagatc
ctgccccaggacaaggagtactatgtggtccaggagcccggccagagccccatattctgg
tatgccccagagtccctgtctgacaatgtcttctcccgggaatccgatgtctggagtttt
ggggtcgtgctgtatgagctttacacctacagtgagaagaacaggagcccttcagcggag
tttctgcgcatgatgggatgtgacagaacgatgcccatcctttgccacttgctggagctt
ctcaaggaaggcaaaaggctgcccactcctcctggctgcccatgggaggtgcatgagcta
atgcggagctgctgggctcacaacccgtgggaacggccgtccttcagtgctctgggcccc
cagatcaacgcactgtgggatgaacggagcagtggccgggggtag
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