Thauera aromatica: Tharo_2628
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Entry
Tharo_2628 CDS
T05381
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
tak
Thauera aromatica
Pathway
tak00010
Glycolysis / Gluconeogenesis
tak00020
Citrate cycle (TCA cycle)
tak00620
Pyruvate metabolism
tak00785
Lipoic acid metabolism
tak01100
Metabolic pathways
tak01110
Biosynthesis of secondary metabolites
tak01120
Microbial metabolism in diverse environments
tak01200
Carbon metabolism
tak01210
2-Oxocarboxylic acid metabolism
Module
tak_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tak00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Tharo_2628
00020 Citrate cycle (TCA cycle)
Tharo_2628
00620 Pyruvate metabolism
Tharo_2628
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Tharo_2628
Enzymes [BR:
tak01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Tharo_2628
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AVR89521
UniProt:
A0A2R4BQ98
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All DBs
Position
2822597..2825278
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AA seq
893 aa
AA seq
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MTGTNKLLPYTDTDAQETKEWLEALAAVVEHEGPERAHYLIESLIAAAREEGVNIPYSAN
TAYINTIPVEQQPSYPGDPDMEIKIHSYIRWNAMAMVVRANKNTNVGGHIASFASAAALY
DVGFSHFWHAPSADHDGDLIYFQGHSVPGIYARAYMLGRFTEEQMDNFRQEVGGKGISSY
PHPWLMPDFWQFPTVSMGLGPLCAIYAARFMKYLASRNLIDPARAARRKVWAFLGDGETD
EVESLGAIGMAGRERLDNLVFVINCNLQRLDGPVRGNGKIIQELEAEFRGAGWNVIKVIW
GTHWDALFARDQKGLLKQRMMELCDGDYQTFKAKDGAYVREHFFNTPELRALVADWTDEQ
VWNLNRGGHDLFKIYAAYKEANEHQGQPTLILAKTIKGFGMGQAGEAMNISHQQKKMDVE
AIRRFRDRFGLPVPDDQIKDLPYLKFAEDSPEYRYLREHRMNLGGFLPQRRRKADALPVP
ALEAFAALLKASGEGRELSTTMAVVRMMNTLLKDKQIGRHVVPIVPDESRTFGMEGMFRQ
YGIWNQEGQKYLPEDHDQLMFYKESQTGQVLQEGINEAGAMADWIAAGTAYSVHGVQMIP
FYIFYSMFGLQRTMDLCWAAADQRTRGFLIGGTAGRTTLNGEGLQHEDGHSLLLANMIPN
CISYDPTFQYEVAVIVQDGLHRMFAEQEDLYYYITVMNENYEHPEMPEGAAADILKGLYL
FRKGAEGKGPRAQLLGSGAIFREVIAAAELLRNDWGVEVDLWGAPSFNELARNGHDVERW
NLLHPMEEPKKSHVEEKLGGTEGPIIAATDYIRMFPEQIRSQLKKTYVTLGTDGFGRSDT
REQLRHFFEVDRHWVTLAALKALADDGVIGRDRVAAAMLKYNLDPNKPNPLSV
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgaccggaacgaacaagcttctcccgtacaccgacaccgacgcgcaggagaccaaggaa
tggctggaggcgctggccgccgtcgtcgagcacgaaggccccgagcgcgcccattacctg
atcgaatccctgatcgccgccgcccgcgaggaaggggtgaacattccctactcggcgaac
accgcgtacatcaacaccattcccgtcgagcagcagccgtcctatcccggcgacccggac
atggaaatcaagatccattcctacatccgctggaatgcgatggcgatggtggtgcgcgcc
aacaaaaacaccaacgtcggcggccacatcgcctccttcgcctccgccgccgcactctac
gacgtcggcttctcgcatttctggcacgccccttcggccgaccatgacggcgacctgatc
tacttccagggccattcggtacccgggatctacgcccgcgcctacatgctcgggcgcttc
accgaagagcagatggacaacttccgccaggaagtgggcgggaaggggatttcctcctac
ccgcatccctggctgatgccggatttctggcaatttccgacggtgtcgatggggctcggc
ccgctgtgcgcgatctacgccgcacggttcatgaaataccttgccagccgcaacctgatc
gacccggcgcgcgccgcccggcgcaaggtgtgggccttcctcggcgacggcgaaaccgac
gaggtcgagtcgctcggcgccatcggcatggccgggcgcgagcgcctcgacaacctcgtc
ttcgtcatcaactgcaacctgcagcgcctggacggcccggtgcgcggcaacggcaagatc
atccaggaactggaagccgagttccgcggcgcgggctggaacgtcatcaaggtgatctgg
ggcacgcactgggacgcgctgttcgcccgcgaccagaaaggtctgctcaagcagcgcatg
atggaactgtgcgacggcgactaccagaccttcaaggcgaaggacggcgcgtatgtgcgc
gagcatttcttcaacacgcccgagctgcgcgcgctggtggccgactggaccgacgagcag
gtttggaacctgaaccgcggcggccacgacctgttcaagatctacgccgcctacaaggag
gccaacgaacaccagggccagcccacgctgatcctggcgaagacgatcaagggcttcggc
atgggccaggccggtgaggcgatgaacatctcgcaccagcagaagaagatggatgtcgag
gccatccgccgcttccgcgaccgcttcggcctgccggtacccgacgaccagatcaaggac
ctgccctacctgaagttcgccgaggattcgcccgagtaccgctacctgcgcgaacaccgc
atgaacctgggcggcttcctgccccagcgccggcgcaaggccgacgccctgccggtgccg
gcgctggaagcctttgccgcgctgctgaaggcttcgggagagggccgcgagctgtcgacg
acgatggccgtggtgcggatgatgaacaccctcctcaaggacaagcagatcggccgccat
gtggtcccgatcgtgcccgacgagagccgcaccttcggcatggaagggatgttccgccag
tacggcatctggaaccaggaagggcagaaatacctgcccgaagaccatgaccagctgatg
ttctacaaggagtcccagaccggccaggtgctgcaggaaggcatcaacgaggccggggcg
atggccgactggatcgccgccggcaccgcctacagcgtgcacggcgtgcagatgatccct
ttctacatcttctactcgatgttcggcctgcagcgcacgatggacctgtgctgggcggcg
gcggaccagcgcacccgcggcttcctgatcggcggcaccgccgggcgcaccacgctcaac
ggcgaaggcctgcagcacgaggacggccacagcctgctgctcgccaacatgatcccgaac
tgcatcagctacgacccgaccttccagtacgaggtcgcggtgatcgtgcaggacggcctg
caccggatgttcgccgagcaggaagacctctactactacatcacggtgatgaacgagaac
tacgaacatcccgagatgcccgaaggggccgcagccgacatcctcaagggcctgtacctg
ttccgcaagggcgccgagggcaagggcccgcgcgcgcagctgctgggttcgggcgcgatc
ttccgcgaagtgatcgccgccgccgaactgctcaggaacgactggggcgtggaagtcgac
ctctggggcgcaccgagcttcaacgaactggcccgcaacggtcacgacgtcgagcgctgg
aacctgctccacccgatggaagagccgaagaagtcgcacgtggaagaaaagctcggcggc
accgaaggcccgatcatcgccgccaccgattacatccgcatgttccccgaacagatccgc
tcgcagttgaagaagacgtacgtgacgctcggcaccgacggcttcggccgctccgacacc
cgcgagcagttgcgccatttcttcgaggtcgaccgccactgggtgacgctggccgcgctg
aaggccctcgccgatgacggcgtgatcggccgcgaccgggtcgccgcagcgatgctcaag
tacaacctcgacccgaacaagccgaacccgctctcggtctga
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