KEGG   Thermobifida alba: FOF52_20930
Entry
FOF52_20930       CDS       T08159                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
talx  Thermobifida alba
Pathway
talx03030  DNA replication
talx03410  Base excision repair
talx03420  Nucleotide excision repair
talx03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:talx00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    FOF52_20930 (ligA)
   03410 Base excision repair
    FOF52_20930 (ligA)
   03420 Nucleotide excision repair
    FOF52_20930 (ligA)
   03430 Mismatch repair
    FOF52_20930 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:talx03032]
    FOF52_20930 (ligA)
   03400 DNA repair and recombination proteins [BR:talx03400]
    FOF52_20930 (ligA)
Enzymes [BR:talx01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     FOF52_20930 (ligA)
DNA replication proteins [BR:talx03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     FOF52_20930 (ligA)
DNA repair and recombination proteins [BR:talx03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     FOF52_20930 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     FOF52_20930 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     FOF52_20930 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      FOF52_20930 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD PTCB-BRCT HHH Nlig-Ia HHH_3 Auto_anti-p27 DUF3701 BRCT_2 DUF7741
Other DBs
NCBI-ProteinID: UPT23098
LinkDB
Position
4705271..4707466
AA seq 731 aa
MSAPHPTPADDIPADVRERHARLSQDLDDHSYRYYLGSPIVSDAEYDRMMAELRELEDRY
PSLVTPDSPTQKAGAPISNEFAPVEHLERMQSLDNAFDDEQLTAWAHRVGAEVPVEAFLC
ELKIDGLAVDLVYEKGRLVRAATRGDGRVGEDITLNIRTIDAVPLRLDESVHPAPELLEV
RGEVFLPATAFEELNARLADEGKPPFANPRNAAAGSLRQKDPRVTASRPLSMLVHGVGAH
RGVAFTHQSQSYEMLAAWGLPVSDRTRVVSSLDEVRAYIAHYAEHRHDPEYEIDGVVVKV
DDVALQRRLGSTSRAPRWAIAYKYPPEEVTTTLLDIKTSVGRTGRVTPYAVLEPVRVAGS
EVEFATLHNAQEVARKGVLIGDTVVVRKAGDVIPEVVGPVLDKRTGAERPFVMPAECPEC
GTPLGQQKEGDVDLRCPNTRYCKGQLRERLFFIAGRKALDIEALGYVAATALTQPLEPAE
PPLRDEGDLFNLTVEQLLPIRTLVLDPDTAEPKLDPKTGEPKVVTFFANQKGEPKKTVEK
LFEQLEEAKRRPLWRVLVALSIRHVGPRAAEDLARHFRSLDAIAQASEEELVAVDGIGPT
IARSIVDWFAVDWHREIVEKWRAAGVRMAEEGADEGPRLLDGVTVVVTGSLEDYSRDGAK
EAVQELGGKVTGSVSKKTDFVVVGANPGSKYDKAVKLGVPVLDEAGFRVLLTQGPEAATA
ARLAVGETPED
NT seq 2196 nt   +upstreamnt  +downstreamnt
gtgagcgcaccacacccgacccccgccgacgacatccccgccgacgtgcgggaacggcac
gcgcggctgagccaggacctcgacgaccacagctaccgctactacctcggatcgccgatc
gtctccgacgccgagtacgaccggatgatggcggagctgcgggagctggaggaccggtac
ccgtcgctggtcaccccggactcgcccacccagaaggccggcgcccccatcagcaacgag
ttcgcgccggtcgagcacctggagcggatgcagagcctggacaacgcgttcgacgacgag
cagctgacggcctgggcgcaccgggtcggcgccgaggtcccggtcgaggcgttcctgtgc
gaactcaagatcgacggcctggccgtggacctggtgtacgagaagggccgcctggtgcgc
gccgccacccgcggggacggccgggtcggcgaggacatcaccctcaacatccgcaccatc
gacgcggtcccgctccgcctggacgagtccgtgcaccccgcgcccgagctgctggaggtg
cgcggtgaggtgttcctgcccgccacggcgttcgaggagctcaacgcccggctcgccgac
gagggcaaaccgccgttcgccaacccccgcaacgccgcggccgggtcgctgcggcagaag
gacccgcgggtcaccgcctcccggccgctgagcatgctggtgcacggcgtcggcgcgcac
cgcggggtcgccttcacccaccagtcgcagtcctacgagatgctggcggcctgggggctg
ccggtcagcgaccgcaccagggtggtctccagcctcgacgaggtccgcgcctacatcgcc
cactacgccgagcaccgccacgaccccgagtacgagatcgacggcgtcgtggtcaaggtc
gacgacgtcgcgctgcagcgccgcctcggctccaccagccgcgccccgcgctgggcgatc
gcctacaagtacccgcccgaggaggtcaccaccacgctgctcgacatcaagaccagcgtg
ggccgcaccggccgggtcaccccgtacgcggtgctggagccggtgcgggtcgccggctcc
gaggtcgagttcgccaccctgcacaacgcccaggaggtggcccgcaagggcgtgctgatc
ggcgacaccgtggtggtgcgcaaggccggggacgtcatcccggaggtcgtggggccggtg
ctggacaagcgcaccggggccgagcggcccttcgtgatgcccgccgagtgccccgagtgc
ggcaccccgctcggccagcagaaggagggcgacgtcgacctgcgctgccccaacacccgc
tactgcaaggggcagctgcgtgaacggctgttcttcatcgccggacgcaaggccctcgac
atcgaggcgctgggctacgtggcggccaccgccctgacccagccgctggaaccggccgag
ccgccgctgcgcgacgagggcgacctgttcaacctcaccgtcgagcagctgctgccgatc
cgcaccctggtcctcgaccccgacaccgccgagccgaaactcgacccgaaaaccggcgag
cccaaggtggtgaccttcttcgccaaccagaagggcgagccgaagaagaccgtcgagaag
ctgttcgagcagctggaggaggccaagcggcgcccgctgtggcgggtgctggtcgcgctg
tccatccggcacgtcggcccccgcgcggccgaggacctcgcccgccacttccgctccctg
gacgccatcgcccaggccagtgaggaggagctggtggcggtcgacgggatcggcccgacc
atcgcgcgctccatcgtcgactggttcgcggtcgactggcaccgcgagatcgtcgagaag
tggcgggccgccggggtccgcatggcggaggagggcgccgacgagggcccccggctgctg
gacggcgtcaccgtggtcgtcaccggttcgctggaggactacagccgggacggggccaag
gaggccgtgcaggaactcggcggcaaggtgaccggatcggtgtccaagaagaccgacttc
gtggtggtcggcgcgaaccccggcagcaagtacgacaaggctgtcaagctcggtgtgccg
gtcctcgacgaggcggggttccgggtgctgctcacccaggggccggaagcggccacggcg
gcacggctggccgtgggggagacccccgaggactga

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