Thermomonospora curvata: Tcur_1644
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Entry
Tcur_1644 CDS
T01127
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
tcu
Thermomonospora curvata
Pathway
tcu00010
Glycolysis / Gluconeogenesis
tcu00020
Citrate cycle (TCA cycle)
tcu00620
Pyruvate metabolism
tcu00785
Lipoic acid metabolism
tcu01100
Metabolic pathways
tcu01110
Biosynthesis of secondary metabolites
tcu01120
Microbial metabolism in diverse environments
tcu01200
Carbon metabolism
tcu01210
2-Oxocarboxylic acid metabolism
Module
tcu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tcu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Tcur_1644
00020 Citrate cycle (TCA cycle)
Tcur_1644
00620 Pyruvate metabolism
Tcur_1644
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Tcur_1644
Enzymes [BR:
tcu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Tcur_1644
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Transket_pyr
AA_kinase
Radical_SAM
Motif
Other DBs
NCBI-ProteinID:
ACY97220
UniProt:
D1ABI4
LinkDB
All DBs
Position
complement(1914490..1917255)
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AA seq
921 aa
AA seq
DB search
MASGRQRFSIISDGLPSQLPDVNPDETREWLESLDTVIKTEGRTRARYLMLRLLERAREQ
QVGVPGLRSTDYINTIPPEREPWFPGDEHIERRIRAYIRWNAAVMVSRANRPELSVGGHI
ATYASAASLYEVGFNHFFRGKDHGESGDQVFIQGHAAPGIYARAFLEGRLTEQQLDGFRQ
EISHPGGGLSSYPHPRLMPDFWEFPTVSMGLAPINAIYQARFNRYLYNRKIKDTSRSHVW
AFLGDGEMGEPESLGAIGLAAREELDNLTFVINCNLQQLDGPVRGNGKIIQELEAFFRGA
GWNVIKVIWGRDWDPLLAKDVDGVLVNKMNTTPDGQFQTYSVESGAYIREHFFGDDPRLR
KMVEHLSDDEIRRLSRGGHDYRKLYAAFKAAREHVGQPTVILAHTIKGWTLGPDFEARNA
THQMKKLTKAELKEFRDRLYLDIPDSALDADLPPYYHPGEDSEEIEYMRERRAALGGYLP
KRVVRAKPLTLPGDSVYGELMKGSGKQKVATTMAFVRLLKDLMKDKNIGARFVPIAPDEF
RTFGMDSLFPTAKIYSPHGQTYDPVDRKLLLSYKESTEGQLLHEGISEAGAMGSMTAAGT
CYATHGEHMIPVYIFYSMFGFQRTGDFMWALADQMGRGFMLGATAGRTTLTGEGLQHADG
HSPLLASANPACVYYDPAWAFELAVIIKDALRRMYGSSPEHPNGEDIFYYLTVYNEPYQQ
PPAPENLDTEGLLKGLYLYSRAPQGINGTYPRAQILASGVAVRWALEAQKMLAEDWGVGA
DVWSATSWTELRRDGLACDEWNTLHPDQPQRVPYVTRRLENAPGPVVAVSDFMRAVPDQI
APWVPQDFTSLGTDGFGFSDTRAASRRFFHVDAASITLTVLTRLARRGDVKPDVLRQAIE
RYDLDRPISEVFAVSAQPNRA
NT seq
2766 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggacgccaacgcttttcgatcatcagcgacgggctgccgagccagctcccg
gacgtcaaccctgacgagacccgggagtggctggaatcgctcgacacggtcatcaagacc
gagggccgcactcgcgcgcgctacctgatgctccgcctgctggagcgggcccgcgagcag
caggtgggcgtgccggggctgcgcagcaccgactacatcaacaccatcccgccggagcgg
gagccgtggttccccggtgatgagcacattgagcgccgcatccgcgcctacatccgctgg
aacgcggccgtcatggtctcccgggccaaccggcccgaactgagcgtcggcgggcacatc
gccacctacgcctcggccgcctcgctgtatgaggtcggcttcaaccacttcttccgtggc
aaggaccacggcgaatccggcgaccaggtgttcatccaggggcatgccgcgccgggcatc
tacgcccgcgccttcctggagggacggctgaccgagcagcagctggacgggttccgccag
gagatctcccatcccggcggggggctcagctcctacccgcacccgcggctgatgcccgac
ttttgggagttccccaccgtctccatggggctggctcccatcaacgccatctaccaggcc
cgtttcaaccgctacctgtacaaccgcaagatcaaggacacctcgcgctcgcacgtgtgg
gcgttcctgggcgacggcgagatgggcgagccggagtcgctgggcgccatcgggctggcc
gcgcgcgaggagctggacaacctcaccttcgtcatcaactgcaacctgcagcagctcgac
ggcccggtccgcggcaacggcaagatcatccaggagctggaggcgttcttccgcggcgcc
ggctggaacgtcatcaaggtcatctggggccgcgactgggacccgctgctggccaaggac
gtcgacggcgtgctggtcaacaagatgaacaccacgccggacgggcagttccagacctac
agcgtggagtcgggcgcctacatccgcgagcacttcttcggcgacgacccgcggctgcgc
aagatggtcgagcacctgtccgacgatgagatccgcaggctctcgcgcggcgggcacgac
taccgcaagctgtatgcggccttcaaggcggcgcgcgagcacgtcgggcagcccacggtg
atcctcgcccacaccatcaagggctggacgctggggccggacttcgaggcccgcaacgcc
acccaccagatgaagaagctcaccaaggccgagctgaaggagttccgggaccggctgtac
ctggacatccccgactcggccctggacgccgacctgccgccgtactaccaccccggggag
gactccgaggagatcgagtacatgcgcgagcggcgcgccgcgctcggcggctacctgccc
aagcgggtggtgcgcgccaagccgctcacgctgcccggcgactcggtctacggcgagctg
atgaaggggtccggcaagcagaaggtggccaccaccatggccttcgtccggctgctgaag
gacctgatgaaggacaagaacatcggggcccgcttcgtgccgatcgcccccgatgagttc
cgcaccttcggcatggactcgctgttccccaccgccaagatctactcgccgcacgggcag
acctacgacccggtggaccgcaagctgctgctgagctacaaggagtccaccgagggccag
ctgctgcacgagggcatcagcgaggccggcgcgatgggctcgatgaccgccgcgggcacc
tgctacgccacccacggcgagcacatgatcccggtctacatcttctattcgatgttcggc
ttccagcgcaccggcgacttcatgtgggcgctggccgaccagatgggccgcgggttcatg
ctgggcgccaccgccggccgcaccacgctgaccggcgagggcctgcagcacgccgacggg
cactccccgctgctggcctccgccaaccccgcctgcgtctactacgacccggcctgggcc
ttcgagctggcggtgatcatcaaggacgcgctgcgccgcatgtacggctcttctcccgag
caccccaacggcgaggacatcttctactacctcaccgtctacaacgagccgtaccagcag
ccgcccgccccggagaacctggacaccgagggcctgctcaagggcctgtacctgtactcc
agggcgccccagggcatcaacggcacctacccgcgggcccagatcctggcctcgggggtg
gcggtgcgctgggcgctggaggcccagaagatgctggccgaggactggggcgtgggcgcg
gacgtgtggtcggccacctcctggaccgagctgcgccgcgacggcctggcctgcgacgag
tggaacaccctccaccccgaccagccgcagcgggtgccgtatgtcacccgtcgcctggag
aacgcccccggcccggtggtggcggtgtcggacttcatgcgcgcggtgccggaccagatc
gccccgtgggtgccgcaggacttcacctcgctgggcaccgacgggttcggcttctccgac
acccgggcggcctcccgccggttcttccacgtggacgccgcctcgatcacgctgaccgtg
ctgacccgcctggcccgccgcggcgacgtcaagccggacgtgctgcgccaggccatcgag
cgctacgacctggaccggccgatctcggaggtgttcgccgtctccgcacagcccaacagg
gcctga
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