KEGG   Thermomonospora curvata: Tcur_2292
Entry
Tcur_2292         CDS       T01127                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
tcu  Thermomonospora curvata
Pathway
tcu00270  Cysteine and methionine metabolism
tcu00450  Selenocompound metabolism
tcu00670  One carbon pool by folate
tcu01100  Metabolic pathways
tcu01110  Biosynthesis of secondary metabolites
tcu01230  Biosynthesis of amino acids
tcu04980  Cobalamin transport and metabolism
tcu04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:tcu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Tcur_2292
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Tcur_2292
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Tcur_2292
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Tcur_2292
   04980 Cobalamin transport and metabolism
    Tcur_2292
Enzymes [BR:tcu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Tcur_2292
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Gp23
Other DBs
NCBI-ProteinID: ACY97858
UniProt: D1A2R0
LinkDB
Position
2673696..2677169
AA seq 1157 aa
MSATPQSLRQALRERVVVADGAMGTMLQAHNPTLDDFQGYEGCNEILNVTRPDIVRAVHA
AYLDAGVDCVETNTFGANLGNLGEYGITDRIEELAEAGARIAREVADSYSTPERPRWVIG
SIGPGTKLPTLGHVSYGELRESYRRTAAGLIAGGAHALLVETCQDLLQVKAALNGAKQAV
AEAGADVVLIAQVTIEQNGAMLLGSEIGAALTALEPLGIDLIGLNCATGPAEMSEHLRYL
SRHARVGLSCMPNAGLPELTPDGARYPLTPQELADAHDAFTRDYGLSLVGGCCGTTPEHL
RLVVERVRGRELAPRRPRPEPGASSLYQHVPFKQDTSYLAIGERTNANGSKAFREAMLAE
RWDDCVRIARDQARDGAHMIDLCVDYVGRDGVADMKELAFRLATASTLPIMLDSTEPAVL
RAGLEMLGGRAVVNSVNYEDGRGPGSRFHRTMTAVREHGAAVVAMCIDEGGQARTREDKV
RIACEIIEDLTGNWGMRLEDIVVDCLTFPIATGQEETRRDALETIEAIAELKRRYPQVQT
TLGISNVSFGLNPAARVVLNSVFLNECVNAGLDSAIVHASKILPMNRIPDEQRQVALDMV
YDRRREGYDPLQRFMELFEGVSAKELRASRAQELAALPLWERLKRRIIDGEANGMEADLD
EALQSRPALEIINDVLLDGMKTVGDLFGSGQMQLPFVLQSAEVMKAAVAYLEPHMEKSAD
GGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVINLGIKQPISAIVEAAKEHRADVIGM
SGLLVKSTVVMKENLEELNARGLARQWPVLLGGAALTRAYVEQDLAELFDGEVRYARDAF
EGLRLMDAFMAVKRGEEGAQLPPLRKRRVASGAKLKVTAPEDMPARSDVATDNPVPEPPF
WGDRIVKGIPLADYAAFLDERATFMGQWGLKPARGGDGPSYEELVETEGRPRLRMWLDRI
QSEGLIEAAVVYGYFPAVSEGDDLVILNDDGSERERITFPRQRRDRHLCLADFFRPRESG
ETDVVAFQLVTVGAKVSQATAELFAKNSYREYLELHGLSVQLTEALAEYWHARVREEIGF
GDQDPADLDGFFKVDYRGARYSFGYPACPDLENRAVVMRLLRPERIGVTLSEEFQLVPEQ
STDALIAHHPEAKYFNV
NT seq 3474 nt   +upstreamnt  +downstreamnt
atgagcgctaccccacagtcgttgcgtcaggccctgcgagaacgagtcgtcgtggccgac
ggcgcgatgggaacgatgctccaggcccacaaccccacgctggacgatttccaggggtat
gagggctgcaacgagatcctcaacgtcacccgtcccgacatcgtccgcgccgtgcacgcg
gcctacctcgacgccggtgtcgactgtgtggagaccaacaccttcggcgccaacctcggc
aacctcggcgagtacggcatcaccgaccggatcgaggagctggccgaggccggcgcccgc
atcgcccgcgaggtcgccgactcctacagcacgcccgagcggccccgctgggtcatcggc
tccatcggcccgggcaccaagctgcccaccctcggccacgtctcctacggcgagctgcgc
gagtcctaccggcgcaccgccgccgggctgatcgccggcggcgcgcacgccctgctggtg
gagacctgccaggacctgttgcaggtcaaggccgccctcaacggcgccaagcaggccgtc
gccgaggccggggcggacgtggtcctcatcgcccaggtgacgatcgagcagaacggcgcc
atgctgctgggctcggagatcggcgccgcgctcaccgcgctggagccgctgggcatcgac
ctgatcggcctcaactgcgccaccggcccggccgagatgagcgagcacctgcggtacctg
tcccgccacgcacgggtcggcctgtcgtgcatgccgaacgccgggctgccggagctgacc
cccgacggcgcccgctacccgctgaccccccaggagctggccgacgcccacgacgccttc
acccgcgactacggcctgtccctggtcggcggctgctgcggcaccacccctgagcacctg
cggctggtcgtcgaacgggtccgcggccgggaactggccccccgcaggccccgtcccgag
cccggcgcctcctcgctgtaccagcacgtgccgttcaagcaggacacctcctacctggcg
atcggggagcgcaccaacgccaacggctccaaggccttccgcgaggcgatgctggccgaa
cgctgggacgactgcgtgcgcatcgcccgcgaccaggcccgcgacggcgcccacatgatc
gacctgtgcgtcgactacgtcggccgcgacggcgtggccgacatgaaggagctggccttc
cggctggccaccgcctccacgctgccgatcatgctggactccaccgagccggccgtgctg
cgggccgggctggagatgctcggcgggcgcgccgtggtcaactcggtcaactacgaagac
ggccgcggacccggctcgcgcttccaccgcaccatgaccgccgtccgcgagcacggcgcc
gccgtggtggcgatgtgcatcgacgaaggcggccaggcccgcacccgcgaggacaaggtc
cgcatcgcctgcgagatcatcgaggacctgaccggcaactgggggatgcgccttgaggac
atcgtcgtcgactgcctgaccttccccatcgccaccggccaggaggagacccgccgcgac
gccctggagaccatcgaggcgatcgccgagctcaagcgccgctacccgcaggtgcagacc
accctcggcatctccaacgtctccttcgggctgaacccggccgcccgggtggtgctgaac
tcggtgttcctcaacgagtgcgtcaacgccggcctggactcggccatcgtgcacgcctcc
aagatcctgccgatgaaccgcatccccgacgagcagcgccaggtcgccctggacatggtc
tacgaccggcgccgcgagggctacgacccgctgcagcggttcatggagctgttcgagggc
gtcagcgccaaggagctgcgcgcctcccgggcccaggagctggccgcgctgccgctgtgg
gagcgcctcaagcgccgcatcatcgacggcgaggccaacgggatggaggccgacctggac
gaggcgctgcagtcccgtcccgccctggagatcatcaacgacgtgctgctggacggcatg
aagaccgtcggcgacctgttcggctccgggcagatgcagctgccgttcgtgctgcagagc
gccgaggtgatgaaggccgcggtggcctacctcgagccgcacatggaaaagtccgccgac
ggcggcaagggccgcatcgtgctggccaccgtcaagggcgacgtgcacgacatcggcaag
aacctggtcgacatcatcctctccaacaacggctacgaggtgatcaacctcggcatcaaa
cagccgatctcggccatcgtggaggccgccaaggagcaccgcgccgacgtgatcggcatg
tccgggctgctggtgaagtccacggtggtcatgaaggagaacctggaggagctcaacgcc
cgcggcctggcccgccagtggccggtgctgctcggcggcgccgcgctgacccgcgcctac
gtcgagcaggacctggccgagctgttcgacggcgaggtccgctatgcccgcgacgccttt
gagggcctgcggctgatggacgccttcatggccgtcaagcgcggcgaggagggcgcccag
ctgccgccgctgcgcaagcggcgggtcgcaagcggcgcgaaactgaaggtcaccgcgccg
gaggacatgccggcccgctccgatgtggccaccgacaacccggtgcccgagccgccgttc
tggggcgaccgcatcgtcaagggcatcccgctggccgactacgccgccttcctggacgag
cgggccaccttcatggggcaatggggcctcaagcccgcccgcggcggcgacggcccctcc
tatgaggagctggtggagaccgagggccggccccggctgcgcatgtggctggaccgcatc
cagtccgaggggctgatcgaggccgcggtggtctacggctacttcccggccgtcagcgag
ggcgacgacctggtcatcttgaacgacgacgggtccgagcgcgagcgcatcaccttcccc
cgccagcgccgcgaccggcacctgtgcctggcggacttcttccggccccgggagtcgggg
gagaccgacgtggtggccttccagctggtcaccgtgggcgcgaaggtctcccaggccacc
gccgagctgttcgccaagaactcctaccgcgagtacctggagctgcacgggctgtcggtc
cagctcaccgaggcgctggccgagtactggcacgcccgggtgcgcgaggagatcggcttc
ggcgaccaggaccccgccgacctggacggcttcttcaaggtcgactaccggggcgcccgc
tactccttcggctacccggcctgccccgacctggagaaccgcgccgtggtgatgcggttg
ctgcggccggagcggatcggcgtcaccctctcggaggagttccagctggtgcccgagcag
tccaccgacgcgctcatcgcccaccaccccgaggccaagtacttcaacgtctga

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