Thermomonospora curvata: Tcur_2773
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Entry
Tcur_2773 CDS
T01127
Name
(GenBank) Beta-ketoacyl synthase
KO
K05551
minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
tcu
Thermomonospora curvata
Pathway
tcu00253
Tetracycline biosynthesis
tcu01056
Biosynthesis of type II polyketide backbone
tcu01100
Metabolic pathways
tcu01110
Biosynthesis of secondary metabolites
Module
tcu_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
tcu00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
Tcur_2773
00253 Tetracycline biosynthesis
Tcur_2773
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
tcu01004
]
Tcur_2773
01008 Polyketide biosynthesis proteins [BR:
tcu01008
]
Tcur_2773
Enzymes [BR:
tcu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
Tcur_2773
2.3.1.260 tetracycline polyketide synthase
Tcur_2773
Lipid biosynthesis proteins [BR:
tcu01004
]
Polyketide synthase
Component type
Tcur_2773
Polyketide biosynthesis proteins [BR:
tcu01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
Tcur_2773
Nonaketide PKS
Tcur_2773
Decaketide PKS
Tcur_2773
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
ACY98319
UniProt:
D1A6R5
LinkDB
All DBs
Position
complement(3230131..3231399)
Genome browser
AA seq
422 aa
AA seq
DB search
MSRRAVITGMGVLAPGAVGVKEYWSLLSEGRTAIRTITHFDPSPFRSRMAGECDFDPVKE
GLTRQQIRRLDRAAQFAIVAGREAIADSGLDFDRLDPTRVAVALGCAIGCTTSLEREFVI
GSADGSQWEIDQNYSVPHLYDYVNPSSMAAELAWLVGAEGPTTMVSTGCTSGIDSVGYAA
RLIEEGSADVVISGGTEAPLSPITVVCFDVLRASSTRNDDPATACRPFDRTRDGLVLAEG
SAILIVEELEHARARGARIWGEVAGYASRCNAYHMTGLEPEGREMAEAIEAAMDKARVLP
AHIDYINAHGSGTKQNDLHETGAFKRSLGEEAYRIPISAFKSMIGHSLGAIGSLEIAGCL
LAIQQDLIPPTANLHEPDPLCDLDYVPLVAREKRVHTALTVGSGFGGFQSAMVLRQMGGD
KR
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgtctcgtcgcgctgtgatcacggggatgggtgtactggcgccaggcgccgtcggggtg
aaggagtactggagtctgctgtcggaggggagaacggccatccggacgatcacccacttc
gacccctcgcccttccggtcccgcatggccggcgagtgcgacttcgaccccgtcaaggaa
gggctgacccggcagcagatccgccgtctggaccgcgcggcgcagttcgcgatcgtcgcc
ggcagggaggcgatcgccgactcgggcctggacttcgaccggctggaccccacccgggtc
gccgtggccctcggatgcgcgatcggctgcacgaccagcctggagcgggagttcgtgatc
ggcagtgccgacggcagccagtgggagatcgatcagaactactccgtcccgcacctgtac
gactatgtgaaccccagctcgatggccgccgagctggcctggctggtgggtgcggagggc
cccaccaccatggtctccaccggctgcacctccggcatcgactccgtcggctatgcggcc
cgcctcatcgaggagggcagcgccgatgtcgtgatcagcgggggcaccgaggcgccgttg
tccccgatcaccgtggtctgcttcgatgtgctgcgggccagctcgacccgcaacgacgac
ccggccaccgcctgccgcccgttcgaccggacgcgggacggcctggtgctcgccgaaggc
agcgccatcttgatcgtggaggagctggagcacgccagggcccgcggtgcccggatctgg
ggcgaggtcgccggttacgcctcccgctgcaacgcctaccacatgaccggcctcgaaccc
gagggcagggaaatggcggaggccatcgaggccgcgatggacaaggcgcgggtgctgccg
gcccacatcgactacatcaacgcgcacggctcgggcaccaagcagaacgacctgcacgag
accggcgccttcaaacgcagcctcggcgaggaggcctaccggataccgatcagcgccttc
aaatcgatgatcgggcattcgctcggggcgatcggctccttggagatcgccgggtgcctg
ctggcgatccagcaggacctcatccctccgacggcgaatctgcacgaacccgatcctctg
tgcgacctggactacgtgcccttggtggcgcgcgagaagcgggtccacaccgcgctgacg
gtcggcagcggcttcggcggtttccagagcgcgatggtcctgcggcagatgggcggagac
aagcgatga
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