Thiomicrospira cyclica: Thicy_0699
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Entry
Thicy_0699 CDS
T01517
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
tcy
Thiomicrospira cyclica
Pathway
tcy00010
Glycolysis / Gluconeogenesis
tcy00020
Citrate cycle (TCA cycle)
tcy00620
Pyruvate metabolism
tcy00785
Lipoic acid metabolism
tcy01100
Metabolic pathways
tcy01110
Biosynthesis of secondary metabolites
tcy01120
Microbial metabolism in diverse environments
tcy01200
Carbon metabolism
tcy01210
2-Oxocarboxylic acid metabolism
Module
tcy_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tcy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Thicy_0699
00020 Citrate cycle (TCA cycle)
Thicy_0699
00620 Pyruvate metabolism
Thicy_0699
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Thicy_0699
Enzymes [BR:
tcy01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Thicy_0699
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AEG31471
UniProt:
F6DC85
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Position
845947..848610
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AA seq
887 aa
AA seq
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MSDQFIDQDTQETQEWLDALEAVVEFEGAEKAQHLIATLIEKARVHGIDIPYSANTPYIN
TIAQEEQANYPGDLSIERRIRAILRWNAMAMVVKANKATSVGGHIASYASSCTLYEVGMN
HFFKGADHPVGGDMVFFQGHTAPGMYARAFMEGRLEEDQLNNFRQEVDGNGLSSYPHPWL
MPDFWQFPTVSMGLGPLMAIYQARFMKYMEKRGLAKTEGRKVWAFLGDGEMDEPESRGAI
QLAQREHLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGMFRGAGWNVIKVLWGTGWDTLL
AKDVTGKLIERMGEVVDGEYQAYKAKSGAYVREHFFGKYPETAALVKDMTDDEIFRLTRG
GHSPRKIYNAYKRATETKNQPSVILAKTVKGYGMGEFGEAANSAHQQKKLDIDGLKYFRD
RFSVPISDEQLENSVPFYRPADDSPIMEYVRARRQELGGALPLRQDVAESLPVPDLAAFK
MLLEGTADREMSSTMAFVRILSIILRDKELGKRIVPIIPDEARTFGMEGLFRQIGIYDPA
GQLYEPVDHDQLMWYKESSNGQVLEEGINEAGAMSSWISAATAYANYGVAMIPFYIYYSM
FGFQRIGDLAWAAGDSRARGFLIGGTAGRTTLEGEGLQHQDGHNLVMFDAIPNCLSYDPT
FGYEMAVIIQDGMRRMLTDKEDVFYYITAMNENYSHPAMPEGVEEGILKGIYPFKKSTAK
KAKHRVQLMGSGTIFREVIAAAEMLEADWGVAADIWGVPSFNLLRREGMEVTRWNTLHPT
AEPKVSYVTEVLAGAEGPFIAATDYIRDYANRIREYVPGDYHVLGTDGFGRSDTREQLRK
FFEVNRYYIVLEALKALKVQGKVTADTLEKAMTQYGLDAEKSFPIHA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgagtgatcaattcattgatcaagatacgcaagaaacgcaagaatggctcgatgcttta
gaggctgttgttgaatttgaaggcgctgagaaagcgcagcatttaatcgcaaccttaatc
gaaaaagcccgtgttcacggcatcgacattccttattctgcaaatactccctacatcaat
accattgcccaagaagagcaagctaattaccccggtgatttaagtattgaacgtcgtatt
cgcgctattttgcgttggaatgccatggcgatggttgtaaaagcgaataaagcaaccagc
gttggtggtcatattgcgtcttacgcatccagttgcaccttgtatgaagtgggtatgaac
catttctttaaaggcgctgaccatccggttggtggtgatatggtgttttttcagggacac
acagcacctggtatgtatgcgcgtgcttttatggaggggcgtttagaagaggatcaactc
aataatttccgtcaagaagtcgatggcaatggattgtcctcatatccacatccttggctc
atgcccgatttttggcaatttcccaccgtatccatgggtcttggtcctttaatggcgatt
taccaggcccgttttatgaaatatatggaaaagcgcggattggctaaaaccgagggtcgt
aaagtctgggcgtttttgggtgatggagagatggacgagcccgaatcacgcggtgctatt
cagttagcccaacgcgaacatctggataatcttatttttgtggtcaactgtaacctacag
cggttagatggaccagtacgtggtaacggcaaaattattcaagaactcgaaggtatgttc
cgtggcgcgggttggaatgtaatcaaagtgctatggggtaccggttgggacacattactg
gcgaaggatgttactggtaagctgattgagcggatgggcgaagtggttgatggtgaatac
caggcctacaaagcaaaaagtggtgcttatgttcgtgagcatttctttggcaagtatcca
gaaacagccgcattggtcaaggatatgaccgatgatgaaattttccgtttaacccgcgga
ggacactcgccacgcaaaatttataatgcttataagcgagcaaccgaaactaaaaatcag
ccatctgttattttagcgaaaacggttaagggctatggcatgggtgagtttggtgaggcc
gctaacagtgcgcatcaacagaaaaaacttgatatcgacggcttgaaatatttccgtgat
cgtttttcggtgccaatttccgatgagcaacttgaaaatagtgtgcctttttatcgtcca
gccgatgacagtccgattatggaatatgtgcgagcgcgccgtcaggaactcggtggtgcg
cttccattgcgccaggatgtagctgaaagcttgcctgtgcctgatttagcggcatttaaa
atgctgctagaaggcacggccgatcgtgaaatgtcttctaccatggcttttgtgcgcatt
ttgtctattattctgcgtgataaagagttgggtaaacgcatcgtgccgattattcctgat
gaagctcgtacctttggtatggaaggcttatttaggcagattggtatttatgacccagca
gggcaactttatgagccggtcgatcatgaccagctaatgtggtacaaagaatcatccaac
ggtcaggtgcttgaagaaggcattaacgaagcgggtgcgatgtcatcttggatttcggcg
gcaaccgcttatgccaactatggcgtggcgatgattccgttctacatctattactcgatg
tttggttttcagcgcattggtgatttggcctgggccgccggtgattcgcgtgcacgtggt
ttcttgattggcggcacagcagggcgtacaacgctagaaggtgaaggtttacaacatcaa
gatggtcataacctggtaatgtttgatgcaattcctaactgtttgagctatgacccgact
tttggctacgaaatggcggttattattcaggatggtatgcgtcggatgttaactgacaaa
gaagatgtgttttattacatcactgctatgaatgaaaactatagccatcctgcgatgccg
gaaggcgttgaagaaggcatcttaaaaggtatttatcctttcaaaaaatcgactgccaag
aaggcaaaacatcgcgttcagttaatgggctctggcaccattttccgtgaagtgattgcc
gcagctgaaatgctcgaagccgattggggtgtagcagcagacatttggggtgtgcccagc
tttaacctattgcgccgtgagggtatggaagttacgcgttggaataccctgcatccaaca
gccgagccaaaagtatcttatgtgaccgaagtattagcaggtgctgaagggccatttatt
gcggcaaccgactatattcgtgattatgccaaccgcattcgtgaatatgtgccgggtgat
tatcatgtattgggtaccgatggttttggccgttctgatacacgtgagcagttacgtaaa
ttctttgaagtgaatcgttattacatcgtgcttgaagccctaaaagcgttaaaagttcaa
ggcaaggttactgcggatacattagaaaaagcaatgacacagtatggattggatgctgaa
aagagcttcccaattcacgcttaa
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