Triplophysa dalaica: 130427658
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Entry
130427658 CDS
T09616
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
tdw
Triplophysa dalaica
Pathway
tdw00140
Steroid hormone biosynthesis
tdw01100
Metabolic pathways
Module
tdw_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
tdw_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
tdw_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
tdw00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
130427658 (hsd3b1)
Enzymes [BR:
tdw01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
130427658 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
130427658 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
Polysacc_synt_2
GDP_Man_Dehyd
NAD_binding_10
KR
NmrA
RmlD_sub_bind
adh_short
Motif
Other DBs
NCBI-GeneID:
130427658
NCBI-ProteinID:
XP_056611208
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Position
8:10699831..10702901
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AA seq
374 aa
AA seq
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MSLAGEVCVVTGACGFLGEKLVRLLLKEEKLAEIRLLDRNIRSELIQSLDDCRGDTKLSV
FEGDIRECELLRRACSGAALVFHTASLVDVTGAIEYSELYGVNVKGTQLLIETCIQENLA
SFIYTSSIEVAGPNPRGDPIINGNENTPYTSILKFSYSKTKDEAEQICLQANGEILRNGG
RLATCALRPMYIFGEGCRFTLGHMRDGISNGNMLLRISSREAKVNPVYVGNVAYAHLLAA
QALRDHQKRAVMGGNFYYISDDTPPVSYSDFNYAVLSTLGFGMRERHILPLPLLYLLSYF
MELLQVVLSPFLRFTPPLNRQLLTMLNTPFSFSYQKAHRDFGYSPRYDWEEARRRTTEWL
ASVLPTERQQLNSK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtcattggcaggagaagtatgtgtggtgacaggagcgtgtgggtttctgggagaaaag
cttgtcagactgttgctaaaggaggaaaagcttgctgaaatccgactgctggacagaaac
atacgttcggagctaatacagtctcttgatgattgcagaggagatactaaactgagtgtg
tttgagggagacatcagagagtgtgagctgttgagaagagcctgcagtggagcagcactt
gtttttcacactgcatctctcgtcgatgtcactggagcgatagagtacagtgaattatat
ggtgtcaatgttaaaggaacgcaactactgattgagacttgcatacaggagaatctggcc
tcattcatttacacaagcagcattgaggttgctggtccaaatcctcgcggtgatccaatc
atcaacggcaatgagaacacaccttacacctcaattcttaaatttagttacagcaaaacc
aaagatgaggctgaacagatttgccttcaggctaatggagagattctgcgcaacggaggc
cggctggctacctgtgcattaagacccatgtacatcttcggagagggttgtcgctttaca
ttaggtcacatgagggatggaatcagcaatggaaacatgctgcttagaatctcaagtcgt
gaggcaaaagtgaatcctgtttatgtgggaaacgtagcatatgcacatctgctagctgcg
caagccctcagagatcaccaaaagagggcagtgatgggtggaaacttctactacatctca
gatgacaccccacctgtcagctactcagactttaactacgctgttctttcaactttaggc
tttgggatgcgagagagacatattttgcccctcccccttctctatctgctgtcatacttc
atggaattactacaggttgtgctcagcccctttctgagattcaccccacccttaaatcga
cagctactgaccatgttaaacacaccctttagtttctcatatcaaaaggcccacagagat
tttggatatagccctcgctatgactgggaagaggcacgcagacgcactactgaatggcta
gcatctgtcctgcctacagagagacaacaattgaactcaaaataa
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