KEGG   Thermosipho ferrireducens: JYK00_00245
Entry
JYK00_00245       CDS       T07656                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
tfe  Thermosipho ferrireducens
Pathway
tfe03030  DNA replication
tfe03410  Base excision repair
tfe03420  Nucleotide excision repair
tfe03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:tfe00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    JYK00_00245 (ligA)
   03410 Base excision repair
    JYK00_00245 (ligA)
   03420 Nucleotide excision repair
    JYK00_00245 (ligA)
   03430 Mismatch repair
    JYK00_00245 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tfe03032]
    JYK00_00245 (ligA)
   03400 DNA repair and recombination proteins [BR:tfe03400]
    JYK00_00245 (ligA)
Enzymes [BR:tfe01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     JYK00_00245 (ligA)
DNA replication proteins [BR:tfe03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     JYK00_00245 (ligA)
DNA repair and recombination proteins [BR:tfe03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     JYK00_00245 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     JYK00_00245 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     JYK00_00245 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      JYK00_00245 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 HHH PTCB-BRCT Nlig-Ia BRCT_2 DNA_ligase_ZBD HHH_3 HHH_8 5_3_exonuc UPF0758_N RNA_ligase DUF6309 zf-tcix BAR_3
Other DBs
NCBI-ProteinID: QTA38017
LinkDB
Position
50039..52030
AA seq 663 aa
MEKQKIREEIEKLRKEIEYHNYRYYVLADPIISDEEYDKLMKKLIKLEKKYPEFSSPDSP
TQKVGGRVIDGFKTVTHSIPMLSLDNTYTAEEVVNFDNRIKKLLKKEVEYVCELKIDGVS
IALRYENGSLVQAISRGNGTEGDDITENVKKIKSIPLRLFKPLTIEVRGEIYMPVSEFVR
YNKQREDEGLPPFANPRNAAAGTLRQLDSSVVANRNLDSFIYYIVHPEYYNLDSQWEALN
FLKQIGLKVNPHSKLCKTINDVINFWKEWTEKRHSLGYWVDGVVVKVNNFAEQNSLGTTA
KSPKWAIAFKFPAIQARTRIISITYQVGRTGVITPVAELEPVTLEGTIVKRASLHNFDYI
KEKDIKVGDHVFVEKAGGIIPQVVSVIKELRTGSEKEVIPPTSCPVCGGNVGKLTENEVA
LRCMNPHCPQKLKRHLEIFVSRSAFDISGIGEKMAEKIVDAKLINDVSDIFYLTPFDLAQ
LSGVGQKTIANVLKQIEKAKKTPLHKVIVGLGIPLVGEKTAKILAEKFENIDKLSNASYE
ELTSIDGIGPELAKSIVDYFRNEKTREIIEKLKNAGVEMKNIAKTKNEKFSGMTFVITGT
LKNYTRNQIKELIESLGGKVSESVSSKTTYLVVGEKPGSKYQKAKQLGVKILTEEEFMKI
MKT
NT seq 1992 nt   +upstreamnt  +downstreamnt
atggagaaacaaaaaataagagaagaaatagaaaagttaagaaaagaaatcgaatatcat
aattatagatactatgtattggctgacccaataataagtgatgaggaatatgataaactt
atgaaaaagttgataaaattagaaaaaaaatatccagaattttcttccccagattctccc
actcaaaaagttgggggaagagttatagatggattcaaaacagtgacacactccatacct
atgttaagtctcgacaacacctacaccgcagaggaagtagtaaattttgataacagaata
aaaaagcttctaaaaaaggaagttgaatacgtctgtgagttaaagatagacggagtttct
atcgctcttagatatgaaaatggaagtcttgtgcaggcaataagcagagggaatggtaca
gaaggtgatgatataacagaaaatgttaagaaaataaagtcaattcctcttagattgttt
aaacctcttacaattgaagtacgaggagaaatttatatgccagtctcagaatttgttcga
tataacaagcaacgtgaagatgagggacttcccccttttgcaaatccaagaaatgccgct
gcaggaactttaagacagctggattcctcagtagtagcaaatcgaaaccttgattctttt
atatattatattgttcatccagaatactataatttagattcacaatgggaagcactaaat
tttttaaaacaaattggactaaaagttaatccgcattcaaaactatgcaaaactatcaac
gatgttattaacttctggaaagaatggacagaaaaacgacattctctgggatattgggtt
gatggtgttgttgtaaaagtaaacaactttgcagaacaaaatagtctgggaacaaccgca
aaatctccaaagtgggctattgcatttaaatttccggcaattcaagccagaacacgaatt
atttcaataacctaccaggttgggcgcactggagttatcacacctgttgccgaacttgaa
ccagtaactctggaaggaactatagtaaaaagagcttcccttcacaactttgattatata
aaagaaaaagacataaaagtaggagaccatgtctttgttgaaaaagctggtggaataata
ccacaagttgtaagtgtaatcaaagaattacgaactggctcagaaaaagaagtaattcca
ccaacatcctgtcccgtgtgcggaggtaatgtgggaaaactcacagaaaatgaagttgct
ttaagatgtatgaatccacattgtccgcaaaagcttaaacggcatcttgaaatatttgtt
tcaagatccgcgtttgatatttccgggattggcgaaaaaatggcagaaaagatcgttgat
gcaaaattgataaatgatgtctctgatatattttacttaacaccatttgaccttgcacaa
ctaagcggggttgggcaaaaaacaattgcaaacgttttaaaacaaattgaaaaagctaaa
aaaactcccttgcataaagtaatcgtaggcttaggaattcctttagttggcgaaaaaaca
gctaagattctcgctgaaaagttcgaaaatattgacaaactttcaaatgcttcatatgaa
gaacttaccagtattgatggaataggtccggaactggctaaaagtatcgtagattatttt
agaaatgaaaaaaccagagaaatcattgaaaaattgaaaaatgcaggagtagaaatgaaa
aatatagctaaaactaaaaatgaaaaattttctggtatgacctttgttattacaggaacg
ctgaaaaattatacgagaaaccagattaaagaacttattgaaagtcttggtggaaaggtc
tctgaatctgtatcatcaaaaacaacttatttagttgtaggtgaaaaacctggttcaaaa
tatcaaaaagccaaacaacttggcgttaaaatacttaccgaagaagaatttatgaaaatt
atgaaaacctag

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