KEGG   Trachypithecus francoisi (Francois's langur): 117065206
Entry
117065206         CDS       T07225                                 
Symbol
PIK3R1
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
tfn  Trachypithecus francoisi (Francois's langur)
Pathway
tfn01521  EGFR tyrosine kinase inhibitor resistance
tfn01522  Endocrine resistance
tfn01524  Platinum drug resistance
tfn04012  ErbB signaling pathway
tfn04014  Ras signaling pathway
tfn04015  Rap1 signaling pathway
tfn04024  cAMP signaling pathway
tfn04062  Chemokine signaling pathway
tfn04066  HIF-1 signaling pathway
tfn04068  FoxO signaling pathway
tfn04070  Phosphatidylinositol signaling system
tfn04071  Sphingolipid signaling pathway
tfn04072  Phospholipase D signaling pathway
tfn04081  Hormone signaling
tfn04140  Autophagy - animal
tfn04150  mTOR signaling pathway
tfn04151  PI3K-Akt signaling pathway
tfn04152  AMPK signaling pathway
tfn04210  Apoptosis
tfn04211  Longevity regulating pathway
tfn04213  Longevity regulating pathway - multiple species
tfn04218  Cellular senescence
tfn04360  Axon guidance
tfn04370  VEGF signaling pathway
tfn04380  Osteoclast differentiation
tfn04510  Focal adhesion
tfn04550  Signaling pathways regulating pluripotency of stem cells
tfn04611  Platelet activation
tfn04613  Neutrophil extracellular trap formation
tfn04620  Toll-like receptor signaling pathway
tfn04625  C-type lectin receptor signaling pathway
tfn04630  JAK-STAT signaling pathway
tfn04650  Natural killer cell mediated cytotoxicity
tfn04660  T cell receptor signaling pathway
tfn04662  B cell receptor signaling pathway
tfn04664  Fc epsilon RI signaling pathway
tfn04666  Fc gamma R-mediated phagocytosis
tfn04668  TNF signaling pathway
tfn04670  Leukocyte transendothelial migration
tfn04722  Neurotrophin signaling pathway
tfn04725  Cholinergic synapse
tfn04750  Inflammatory mediator regulation of TRP channels
tfn04810  Regulation of actin cytoskeleton
tfn04910  Insulin signaling pathway
tfn04914  Progesterone-mediated oocyte maturation
tfn04915  Estrogen signaling pathway
tfn04917  Prolactin signaling pathway
tfn04919  Thyroid hormone signaling pathway
tfn04923  Regulation of lipolysis in adipocytes
tfn04926  Relaxin signaling pathway
tfn04929  GnRH secretion
tfn04930  Type II diabetes mellitus
tfn04931  Insulin resistance
tfn04932  Non-alcoholic fatty liver disease
tfn04933  AGE-RAGE signaling pathway in diabetic complications
tfn04935  Growth hormone synthesis, secretion and action
tfn04960  Aldosterone-regulated sodium reabsorption
tfn04973  Carbohydrate digestion and absorption
tfn05010  Alzheimer disease
tfn05017  Spinocerebellar ataxia
tfn05020  Prion disease
tfn05100  Bacterial invasion of epithelial cells
tfn05135  Yersinia infection
tfn05142  Chagas disease
tfn05146  Amoebiasis
tfn05160  Hepatitis C
tfn05161  Hepatitis B
tfn05162  Measles
tfn05163  Human cytomegalovirus infection
tfn05164  Influenza A
tfn05165  Human papillomavirus infection
tfn05166  Human T-cell leukemia virus 1 infection
tfn05167  Kaposi sarcoma-associated herpesvirus infection
tfn05168  Herpes simplex virus 1 infection
tfn05169  Epstein-Barr virus infection
tfn05170  Human immunodeficiency virus 1 infection
tfn05171  Coronavirus disease - COVID-19
tfn05200  Pathways in cancer
tfn05203  Viral carcinogenesis
tfn05205  Proteoglycans in cancer
tfn05206  MicroRNAs in cancer
tfn05207  Chemical carcinogenesis - receptor activation
tfn05208  Chemical carcinogenesis - reactive oxygen species
tfn05210  Colorectal cancer
tfn05211  Renal cell carcinoma
tfn05212  Pancreatic cancer
tfn05213  Endometrial cancer
tfn05214  Glioma
tfn05215  Prostate cancer
tfn05218  Melanoma
tfn05220  Chronic myeloid leukemia
tfn05221  Acute myeloid leukemia
tfn05222  Small cell lung cancer
tfn05223  Non-small cell lung cancer
tfn05224  Breast cancer
tfn05225  Hepatocellular carcinoma
tfn05226  Gastric cancer
tfn05230  Central carbon metabolism in cancer
tfn05231  Choline metabolism in cancer
tfn05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tfn05415  Diabetic cardiomyopathy
tfn05417  Lipid and atherosclerosis
tfn05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tfn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    117065206 (PIK3R1)
   04014 Ras signaling pathway
    117065206 (PIK3R1)
   04015 Rap1 signaling pathway
    117065206 (PIK3R1)
   04370 VEGF signaling pathway
    117065206 (PIK3R1)
   04630 JAK-STAT signaling pathway
    117065206 (PIK3R1)
   04668 TNF signaling pathway
    117065206 (PIK3R1)
   04066 HIF-1 signaling pathway
    117065206 (PIK3R1)
   04068 FoxO signaling pathway
    117065206 (PIK3R1)
   04070 Phosphatidylinositol signaling system
    117065206 (PIK3R1)
   04072 Phospholipase D signaling pathway
    117065206 (PIK3R1)
   04071 Sphingolipid signaling pathway
    117065206 (PIK3R1)
   04024 cAMP signaling pathway
    117065206 (PIK3R1)
   04151 PI3K-Akt signaling pathway
    117065206 (PIK3R1)
   04152 AMPK signaling pathway
    117065206 (PIK3R1)
   04150 mTOR signaling pathway
    117065206 (PIK3R1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    117065206 (PIK3R1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    117065206 (PIK3R1)
  09143 Cell growth and death
   04210 Apoptosis
    117065206 (PIK3R1)
   04218 Cellular senescence
    117065206 (PIK3R1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    117065206 (PIK3R1)
   04550 Signaling pathways regulating pluripotency of stem cells
    117065206 (PIK3R1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    117065206 (PIK3R1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    117065206 (PIK3R1)
   04613 Neutrophil extracellular trap formation
    117065206 (PIK3R1)
   04620 Toll-like receptor signaling pathway
    117065206 (PIK3R1)
   04625 C-type lectin receptor signaling pathway
    117065206 (PIK3R1)
   04650 Natural killer cell mediated cytotoxicity
    117065206 (PIK3R1)
   04660 T cell receptor signaling pathway
    117065206 (PIK3R1)
   04662 B cell receptor signaling pathway
    117065206 (PIK3R1)
   04664 Fc epsilon RI signaling pathway
    117065206 (PIK3R1)
   04666 Fc gamma R-mediated phagocytosis
    117065206 (PIK3R1)
   04670 Leukocyte transendothelial migration
    117065206 (PIK3R1)
   04062 Chemokine signaling pathway
    117065206 (PIK3R1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    117065206 (PIK3R1)
   04923 Regulation of lipolysis in adipocytes
    117065206 (PIK3R1)
   04929 GnRH secretion
    117065206 (PIK3R1)
   04915 Estrogen signaling pathway
    117065206 (PIK3R1)
   04914 Progesterone-mediated oocyte maturation
    117065206 (PIK3R1)
   04917 Prolactin signaling pathway
    117065206 (PIK3R1)
   04926 Relaxin signaling pathway
    117065206 (PIK3R1)
   04935 Growth hormone synthesis, secretion and action
    117065206 (PIK3R1)
   04919 Thyroid hormone signaling pathway
    117065206 (PIK3R1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    117065206 (PIK3R1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    117065206 (PIK3R1)
  09156 Nervous system
   04725 Cholinergic synapse
    117065206 (PIK3R1)
   04722 Neurotrophin signaling pathway
    117065206 (PIK3R1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    117065206 (PIK3R1)
  09158 Development and regeneration
   04360 Axon guidance
    117065206 (PIK3R1)
   04380 Osteoclast differentiation
    117065206 (PIK3R1)
  09149 Aging
   04211 Longevity regulating pathway
    117065206 (PIK3R1)
   04213 Longevity regulating pathway - multiple species
    117065206 (PIK3R1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117065206 (PIK3R1)
   05206 MicroRNAs in cancer
    117065206 (PIK3R1)
   05205 Proteoglycans in cancer
    117065206 (PIK3R1)
   05207 Chemical carcinogenesis - receptor activation
    117065206 (PIK3R1)
   05208 Chemical carcinogenesis - reactive oxygen species
    117065206 (PIK3R1)
   05203 Viral carcinogenesis
    117065206 (PIK3R1)
   05230 Central carbon metabolism in cancer
    117065206 (PIK3R1)
   05231 Choline metabolism in cancer
    117065206 (PIK3R1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117065206 (PIK3R1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    117065206 (PIK3R1)
   05212 Pancreatic cancer
    117065206 (PIK3R1)
   05225 Hepatocellular carcinoma
    117065206 (PIK3R1)
   05226 Gastric cancer
    117065206 (PIK3R1)
   05214 Glioma
    117065206 (PIK3R1)
   05221 Acute myeloid leukemia
    117065206 (PIK3R1)
   05220 Chronic myeloid leukemia
    117065206 (PIK3R1)
   05218 Melanoma
    117065206 (PIK3R1)
   05211 Renal cell carcinoma
    117065206 (PIK3R1)
   05215 Prostate cancer
    117065206 (PIK3R1)
   05213 Endometrial cancer
    117065206 (PIK3R1)
   05224 Breast cancer
    117065206 (PIK3R1)
   05222 Small cell lung cancer
    117065206 (PIK3R1)
   05223 Non-small cell lung cancer
    117065206 (PIK3R1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117065206 (PIK3R1)
   05170 Human immunodeficiency virus 1 infection
    117065206 (PIK3R1)
   05161 Hepatitis B
    117065206 (PIK3R1)
   05160 Hepatitis C
    117065206 (PIK3R1)
   05171 Coronavirus disease - COVID-19
    117065206 (PIK3R1)
   05164 Influenza A
    117065206 (PIK3R1)
   05162 Measles
    117065206 (PIK3R1)
   05168 Herpes simplex virus 1 infection
    117065206 (PIK3R1)
   05163 Human cytomegalovirus infection
    117065206 (PIK3R1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117065206 (PIK3R1)
   05169 Epstein-Barr virus infection
    117065206 (PIK3R1)
   05165 Human papillomavirus infection
    117065206 (PIK3R1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    117065206 (PIK3R1)
   05100 Bacterial invasion of epithelial cells
    117065206 (PIK3R1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    117065206 (PIK3R1)
   05142 Chagas disease
    117065206 (PIK3R1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    117065206 (PIK3R1)
   05017 Spinocerebellar ataxia
    117065206 (PIK3R1)
   05020 Prion disease
    117065206 (PIK3R1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117065206 (PIK3R1)
   05418 Fluid shear stress and atherosclerosis
    117065206 (PIK3R1)
   05415 Diabetic cardiomyopathy
    117065206 (PIK3R1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    117065206 (PIK3R1)
   04932 Non-alcoholic fatty liver disease
    117065206 (PIK3R1)
   04931 Insulin resistance
    117065206 (PIK3R1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    117065206 (PIK3R1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    117065206 (PIK3R1)
   01524 Platinum drug resistance
    117065206 (PIK3R1)
   01522 Endocrine resistance
    117065206 (PIK3R1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tfn04131]
    117065206 (PIK3R1)
Membrane trafficking [BR:tfn04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    117065206 (PIK3R1)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 RhoGAP SH2_1 SH3_1 SH3_2 Laminin_I SH3_9 FANCI_S2 FWWh Exonuc_VII_L
Other DBs
NCBI-GeneID: 117065206
NCBI-ProteinID: XP_033035641
LinkDB
Position
Unknown
AA seq 724 aa
MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN
ETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPIAPGSSKTEADVEQQALTLPDLAE
QFAPPDVAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTASVDLEMIDVH
ILADAFKRYLLDLPNPVIPAAVYSEMISLAQEVQSSEEYIQLLKKLIRSPSIPHQYWLTL
QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNE
RQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA
STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKL
DVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMK
RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIID
SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN
ENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACS
VVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA
QQRR
NT seq 2175 nt   +upstreamnt  +downstreamnt
atgagtgctgaggggtaccagtacagagcgttgtatgattataaaaaagaaagagaagaa
gatattgacttgcacttgggtgacatattgactgtgaataaagggtccttagtagctctt
ggattcagtgatggacaggaagccaggcctgaagaaattggctggttaaatggctataat
gaaaccacaggggaaaggggggactttccgggaacttatgtagaatatattggaaggaaa
aaaatctcgcctcccacgccaaagccccggccgcctcggcctcttcctattgcaccaggt
tcttcaaaaactgaagcagatgttgaacaacaagctttgactctcccggaccttgcagag
cagtttgcccctcctgacgttgccccgcctcttcttatcaagctcgtggaagccattgaa
aagaaaggtctggaatgttcaactctatacagaacacagagctccagcaacctggcagaa
ttacgacagcttcttgattgtgatacagcctctgtggacttggaaatgatcgatgtgcac
attttggccgacgctttcaaacgctatctcctggacttaccaaatcctgtcattccagca
gccgtttacagtgaaatgatttctttagctcaagaagtacaaagctccgaagaatatatt
cagctattgaagaagcttattaggtcgcctagcatacctcatcagtattggcttacgctt
cagtatttgttaaaacatttcttcaagctctctcaaacctccagcaaaaatctgttgaat
gcaagagtactctctgaaattttcagccctatgcttttcagattctcagcagccagctct
gataatactgaaaacctcataaaagttatagaaattttaatctcaactgaatggaatgaa
cgacagcctgcaccagcactgcctcctaaaccaccaaaacccactactgtagccaacaac
ggtatgaataacaatatgtccttacaagatgctgaatggtactggggagatatctcgagg
gaagaagtgaatgaaaaacttcgagatacagcagatgggacctttttggtacgagatgca
tctactaaaatgcatggtgattatactcttacactaaggaaagggggaaataacaaatta
atcaaaatatttcatcgagatgggaaatatggcttctctgacccattaaccttcaattct
gtggttgaattaataaaccactaccggaatgaatctctagctcagtataatcccaagctg
gatgtgaaattactttatccagtatccaaataccaacaggatcaagttgtcaaagaagat
aatattgaagctgtagggaaaaaattacatgaatataacactcagtttcaagaaaaaagt
agagaatatgatagattatatgaagaatatacccgtacatcccaggaaatccaaatgaaa
aggacagctattgaagcatttaatgaaaccatcaaaatatttgaagaacagtgccagacc
caggagcgctacagcaaagaatacatagaaaagtttaaacgtgagggcaatgagaaagaa
atacaaaggattatgcataattatgataagttgaagtctcgaatcagtgaaattattgac
agtaggagaagattggaagaagacttgaagaagcaggcagctgagtatcgagaaattgac
aaacgtatgaacagcattaaaccagaccttatccagctgagaaagacgagagaccaatac
ttgatgtggttgactcaaaaaggtgttcggcaaaagaagttgaacgagtggttgggcaat
gaaaacactgaagaccaatattcgctggtggaagatgatgaagatttaccccatcatgat
gagaagacatggaatgttggaagcagcaaccgaaacaaagctgaaaacctgttgcgaggg
aagcgagatggcacttttcttgtccgggagagcagtaaacagggctgctacgcctgctct
gtagtggtggacggcgaagtaaagcattgtgtcataaacaaaacagcgactggctatggc
tttgccgagccctataacttgtacagctctctgaaagaactggtgctacattaccaacac
acctccctcgtgcagcacaacgactccctcaatgtcacactagcctacccagtatatgca
cagcagaggcgatga

DBGET integrated database retrieval system