Trachypithecus francoisi (Francois's langur): 117075371
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Entry
117075371 CDS
T07225
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn00140
Steroid hormone biosynthesis
tfn00980
Metabolism of xenobiotics by cytochrome P450
tfn01100
Metabolic pathways
tfn05204
Chemical carcinogenesis - DNA adducts
Module
tfn_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
117075371 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
117075371 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
117075371 (HSD11B1)
Enzymes [BR:
tfn01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
117075371 (HSD11B1)
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Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
2-Hacid_dh_C
Shikimate_DH
Pyr_redox_3
Pyr_redox_2
NAD_binding_2
AdoHcyase_NAD
Motif
Other DBs
NCBI-GeneID:
117075371
NCBI-ProteinID:
XP_033053561
LinkDB
All DBs
Position
Unknown
AA seq
292 aa
AA seq
DB search
MAFMKKYLLPILGLFMAYYYYSAHEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH
ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV
AAYSASKFALDGFFSSIRKEYSVAKVNVSITLCVLGLIDTETAMKAVSGIINMQAAPKEE
CALEIIKGGALRQEEVYYDSSLWTTLLMRNPCRKILEFLYSTSYNMDRFIKN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctcctccccattctggggctcttcatggcctactactac
tattctgcacatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaagggatcggaagagagatggcttatcatctggcgaagatgggagcccac
gtggtggtaacagcgaggtcaaaagaaactctacagaaggtggtttcccactgcctggaa
cttggagcagcctcagcacactacattgctggcaccatggaagacatgacgttcgcagag
caatttgttgcccaagcaggaaagctcatgggaggactagacatgctcattctcaaccac
atcaccaacacttctttgaatctttttcatgatgatattcaccatgtgcgcaaaagcatg
gaggtcaacttcctcagttatgtggtcctgactgtagctgccttgcccatgttgaagcag
agcaatggaagcattgttgtcgtctcttctttggctgggaaagtggcttatccaatggtt
gctgcctattctgcaagcaagtttgctttggatgggttcttctcctccatcagaaaggaa
tattcagtggccaaggtcaatgtatcaatcactctctgtgttcttggcctcatagacaca
gaaacagctatgaaggcagtttctgggataatcaatatgcaagcagctccaaaggaggaa
tgtgcccttgagatcatcaaagggggagctctgcgccaagaagaagtatattatgacagc
tcactctggaccactcttctgatgagaaatccatgcaggaagatcctggaatttctctac
tcaacgagctataatatggacagattcataaaaaactag
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