Trachypithecus francoisi (Francois's langur): 117076455
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Entry
117076455 CDS
T07225
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn04062
Chemokine signaling pathway
tfn04151
PI3K-Akt signaling pathway
tfn04217
Necroptosis
tfn04550
Signaling pathways regulating pluripotency of stem cells
tfn04630
JAK-STAT signaling pathway
tfn04658
Th1 and Th2 cell differentiation
tfn04659
Th17 cell differentiation
tfn05161
Hepatitis B
tfn05162
Measles
tfn05166
Human T-cell leukemia virus 1 infection
tfn05169
Epstein-Barr virus infection
tfn05200
Pathways in cancer
tfn05203
Viral carcinogenesis
tfn05223
Non-small cell lung cancer
tfn05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
117076455 (JAK3)
04151 PI3K-Akt signaling pathway
117076455 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
117076455 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
117076455 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
117076455 (JAK3)
04659 Th17 cell differentiation
117076455 (JAK3)
04062 Chemokine signaling pathway
117076455 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117076455 (JAK3)
05203 Viral carcinogenesis
117076455 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
117076455 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
117076455 (JAK3)
05161 Hepatitis B
117076455 (JAK3)
05162 Measles
117076455 (JAK3)
05169 Epstein-Barr virus infection
117076455 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
117076455 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tfn01001
]
117076455 (JAK3)
Enzymes [BR:
tfn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
117076455 (JAK3)
Protein kinases [BR:
tfn01001
]
Non-receptor tyrosine kinases
JAK family [OT]
117076455 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
FERM_F1
Jak1_Phl
SH2
ABC1
Kinase-like
Kdo
FERM_C_FAK1
LRR_RI_capping
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
117076455
NCBI-ProteinID:
XP_033055870
LinkDB
All DBs
Position
Unknown
AA seq
1167 aa
AA seq
DB search
MTVAQETKGPTQEGAEWDFPLAASRLCSPFEGPGSLPARQVALMAPPSEETPLIPQRSCS
LLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATED
LSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLDKCHRFGLRKDLASAILDLPVLEHL
FAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPS
LRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLEQLDPAGAAETFHVG
LPGVPGGQDGMGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRL
VTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCH
GPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQSPLGPDYKGCLIRRSPTGT
FFLVGLSRSHSSLRELLAACWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGCSPPTS
SLVQPQSQCQLSQMTFHKIPAESLEWHENLGHGSFTKIYRGCRHEAVDGESRKTEVLLKV
MDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGH
LVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPA
VLSLEMLTDRIPWVAPECLREAQTLNLEADKWGFGATVWEVFSGVTMPISALDPAKKLQF
YEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALA
PRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQL
QHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRH
RARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLD
KDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRM
MGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSTLGPQLDV
LWSGSRGCETHAFTAHPEGKPHSLSFL
NT seq
3504 nt
NT seq
+upstream
nt +downstream
nt
atgacagtggctcaggaaaccaaggggcccacacaggaaggagccgagtgggactttcct
cttgctgcctcccggctctgctctcccttcgaaggcccagggtccctgcctgctaggcaa
gttgcactcatggcacctccaagtgaggagacacccctgatccctcagcgctcctgcagc
ctcttgtccacggaggctggtgccctgcacgtgctactgcccgctcggggccccgggccc
ccccagcgcctatctttctcctttggggaccacttggctgaagacctgtgcgtgcaggct
gccaaggccagcggcatcctgcctgtgtaccactccctctttgctctggccacggaggac
ctgtcctgctggttccccccgagccacatcttctctgtggaggatgccagcacccaagtc
ctgctctacaggattcgcttttacttccccaattggtttgggctggacaagtgccaccgc
ttcgggctacgcaaggatttggccagcgctatccttgacctgccagtcctggagcacctc
tttgcccagcaccgcagtgacctggtgagtggacgcctccctgtgggcctcagcctcaag
gagcagggtgagtgtctcagcctggccgtgctggacctggcccggatggcgcgagagcag
gcccagcggccaggagagctgctgaagactgtcagctacaaggcctgcctacccccaagc
ctgcgcgacctgatccagggcctgagtttcgtgacgcggaggcgtattcggaggacagtg
cgcagggccctgcgccgcgtggccgcctgccaggccgaccggcactcgctcatggccaag
tacattatggatctggagcagctggatccggctggggccgccgagaccttccatgtgggc
ctccctggggtccctggtggccaggacgggatggggctgctccgcgtggctggtgacgga
ggcatcgcctggacccagggagaacaggaggtcctccagcccttctgcgactttccagaa
atcgtagacattagcatcaagcaggccccgcgcgttggcccggccggggagcaccgcctg
gtcactgtcaccaggacagacaaccagattttggaggccgagttcccagggctgcccgag
gctctgtctttcgtggcgctcgtggacggctacttccggctgaccacggactcccagcac
ttcttctgcaaggaggtggcaccgccgaggctgctggaggaggtggcagagcagtgccac
ggccccatcactctggactttgccataaacaagcttaagactgggggctcacgtcctggc
tcctatgttctccgccgcagcccccaggactttgacagcttcctcctcactgtctgtgta
cagagcccccttggtcctgattataagggttgcctcattcggcgcagccccacagggacc
ttctttctggttggcctcagccgatcgcacagcagccttcgagagctcctggcagcctgc
tgggatggggggctgcacgtagatggggtcgcagtgaccctcacctcctgctgtatcccc
agacccaaagaaaagtccaacttgatcgtggtccagagaggttgcagcccacccacgtcc
tccctggttcaaccccaatcccaatgccagctgagtcagatgacatttcacaagatcccc
gctgagagcctagagtggcatgagaacctgggccatgggtccttcaccaagatttaccgg
ggctgtcgccacgaggcggtggatggggagtcccgaaagacagaggtgctgctaaaagtg
atggatgctaagcacaagaactgcatggagtcattcctggaagcagcgagcttgatgagc
caagtgtcataccggcatctcgtgctgctccacggcgtgtgcatggctggagacagcacc
atggtgcaagaatttgtacacctgggggcgatagacatgtatctgcgaaaacgtggccac
ctggtgccagccagctggaagctgcaggtggtcaaacagctggcctacgccctcaactat
ctggaggacaaaggcctcccccacggcaatgtctccgcccggaaggtgctcctggctcgg
gagggggctgatgggagcccgcccttcatcaagctgagtgaccctggggtcagccccgct
gtgttaagcctggagatgctcaccgacaggatcccctgggtggctcccgagtgtcttcgg
gaggcccagacacttaacttggaagctgacaagtggggcttcggtgccacggtctgggag
gtgtttagtggcgtcaccatgcccatcagcgccctggatcctgctaagaaactccaattt
tatgaggaccggcagcagctgccggcccccaagtggacagagctggccctgctgattcaa
cagtgcatggcctatgagccggtccagaggccctccttccgagccgtcattcgtgacctc
aacagcctcatctcttcagactatgagctcctctcagaccccacacctggtgccctggca
cctcgtgatgggctgtggaatggtgcccagctctatgcctgccaagaccccacgatcttc
gaggagagacacctcaagtacatctcacagctgggcaagggcaactttggcagtgtggag
ctgtgccgctatgacccgctaggcgacaacacaggtgccctggtggccgtgaaacagctg
cagcacagcgggccagaccagcagagggacttccagcgggagattcagatcctcaaagca
ctgcacagtgatttcattgtcaagtatcgtggtgtcagctacggcccgggccgccagagc
ctgcggctggtcatggagtacctgcccagcggctgcttgcgcgacttcctgcagcggcac
cgcgcgcgcctcgatgccagccgcctccttctctactcctcgcagatctgcaagggcatg
gagtacctgggctcccgccgctgcgtgcaccgcgacctggccgcccgaaacatcctggtg
gagagcgaggcacacgtcaagatcgctgacttcggcctagctaagctgctgccgcttgac
aaagactactacgtggtccgcgagccgggccagagccccattttctggtatgcccccgaa
tccctctcggacaacatcttctctcgccagtcagacgtctggagcttcggggtcgtcctc
tacgagctcttcacctactgtgacaaaagctgcagcccctcggccgagtttctgcggatg
atgggatgtgagcgggatgtccccgccctctgccgcctcttggaactgctggaggagggc
cagaggctgccggcgcctcctgcctgccctgctgaggttcacgagctcatgaagctgtgc
tgggcccctagcccacaggaccggccatcattcagcaccctgggcccccagctggacgtg
ctgtggagcggaagccgggggtgtgagactcacgccttcactgctcacccagagggcaaa
ccacactccctgtcctttttgtag
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