KEGG   Trachypithecus francoisi (Francois's langur): 117079299
Entry
117079299         CDS       T07225                                 
Symbol
ADCY8
Name
(RefSeq) LOW QUALITY PROTEIN: adenylate cyclase type 8
  KO
K08048  adenylate cyclase 8 [EC:4.6.1.1]
Organism
tfn  Trachypithecus francoisi (Francois's langur)
Pathway
tfn00230  Purine metabolism
tfn01100  Metabolic pathways
tfn01522  Endocrine resistance
tfn04015  Rap1 signaling pathway
tfn04020  Calcium signaling pathway
tfn04022  cGMP-PKG signaling pathway
tfn04024  cAMP signaling pathway
tfn04062  Chemokine signaling pathway
tfn04072  Phospholipase D signaling pathway
tfn04081  Hormone signaling
tfn04082  Neuroactive ligand signaling
tfn04114  Oocyte meiosis
tfn04211  Longevity regulating pathway
tfn04213  Longevity regulating pathway - multiple species
tfn04261  Adrenergic signaling in cardiomyocytes
tfn04270  Vascular smooth muscle contraction
tfn04371  Apelin signaling pathway
tfn04540  Gap junction
tfn04611  Platelet activation
tfn04713  Circadian entrainment
tfn04714  Thermogenesis
tfn04720  Long-term potentiation
tfn04723  Retrograde endocannabinoid signaling
tfn04724  Glutamatergic synapse
tfn04725  Cholinergic synapse
tfn04727  GABAergic synapse
tfn04742  Taste transduction
tfn04750  Inflammatory mediator regulation of TRP channels
tfn04911  Insulin secretion
tfn04912  GnRH signaling pathway
tfn04913  Ovarian steroidogenesis
tfn04914  Progesterone-mediated oocyte maturation
tfn04915  Estrogen signaling pathway
tfn04916  Melanogenesis
tfn04918  Thyroid hormone synthesis
tfn04921  Oxytocin signaling pathway
tfn04923  Regulation of lipolysis in adipocytes
tfn04925  Aldosterone synthesis and secretion
tfn04926  Relaxin signaling pathway
tfn04927  Cortisol synthesis and secretion
tfn04928  Parathyroid hormone synthesis, secretion and action
tfn04934  Cushing syndrome
tfn04935  Growth hormone synthesis, secretion and action
tfn04970  Salivary secretion
tfn04971  Gastric acid secretion
tfn04972  Pancreatic secretion
tfn04976  Bile secretion
tfn05032  Morphine addiction
tfn05163  Human cytomegalovirus infection
tfn05166  Human T-cell leukemia virus 1 infection
tfn05200  Pathways in cancer
tfn05207  Chemical carcinogenesis - receptor activation
tfn05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tfn00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    117079299 (ADCY8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    117079299 (ADCY8)
   04371 Apelin signaling pathway
    117079299 (ADCY8)
   04020 Calcium signaling pathway
    117079299 (ADCY8)
   04072 Phospholipase D signaling pathway
    117079299 (ADCY8)
   04024 cAMP signaling pathway
    117079299 (ADCY8)
   04022 cGMP-PKG signaling pathway
    117079299 (ADCY8)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    117079299 (ADCY8)
   04081 Hormone signaling
    117079299 (ADCY8)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    117079299 (ADCY8)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    117079299 (ADCY8)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    117079299 (ADCY8)
   04062 Chemokine signaling pathway
    117079299 (ADCY8)
  09152 Endocrine system
   04911 Insulin secretion
    117079299 (ADCY8)
   04923 Regulation of lipolysis in adipocytes
    117079299 (ADCY8)
   04912 GnRH signaling pathway
    117079299 (ADCY8)
   04913 Ovarian steroidogenesis
    117079299 (ADCY8)
   04915 Estrogen signaling pathway
    117079299 (ADCY8)
   04914 Progesterone-mediated oocyte maturation
    117079299 (ADCY8)
   04921 Oxytocin signaling pathway
    117079299 (ADCY8)
   04926 Relaxin signaling pathway
    117079299 (ADCY8)
   04935 Growth hormone synthesis, secretion and action
    117079299 (ADCY8)
   04918 Thyroid hormone synthesis
    117079299 (ADCY8)
   04928 Parathyroid hormone synthesis, secretion and action
    117079299 (ADCY8)
   04916 Melanogenesis
    117079299 (ADCY8)
   04925 Aldosterone synthesis and secretion
    117079299 (ADCY8)
   04927 Cortisol synthesis and secretion
    117079299 (ADCY8)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    117079299 (ADCY8)
   04270 Vascular smooth muscle contraction
    117079299 (ADCY8)
  09154 Digestive system
   04970 Salivary secretion
    117079299 (ADCY8)
   04971 Gastric acid secretion
    117079299 (ADCY8)
   04972 Pancreatic secretion
    117079299 (ADCY8)
   04976 Bile secretion
    117079299 (ADCY8)
  09156 Nervous system
   04724 Glutamatergic synapse
    117079299 (ADCY8)
   04727 GABAergic synapse
    117079299 (ADCY8)
   04725 Cholinergic synapse
    117079299 (ADCY8)
   04720 Long-term potentiation
    117079299 (ADCY8)
   04723 Retrograde endocannabinoid signaling
    117079299 (ADCY8)
  09157 Sensory system
   04742 Taste transduction
    117079299 (ADCY8)
   04750 Inflammatory mediator regulation of TRP channels
    117079299 (ADCY8)
  09149 Aging
   04211 Longevity regulating pathway
    117079299 (ADCY8)
   04213 Longevity regulating pathway - multiple species
    117079299 (ADCY8)
  09159 Environmental adaptation
   04713 Circadian entrainment
    117079299 (ADCY8)
   04714 Thermogenesis
    117079299 (ADCY8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117079299 (ADCY8)
   05207 Chemical carcinogenesis - receptor activation
    117079299 (ADCY8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117079299 (ADCY8)
   05163 Human cytomegalovirus infection
    117079299 (ADCY8)
  09165 Substance dependence
   05032 Morphine addiction
    117079299 (ADCY8)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    117079299 (ADCY8)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    117079299 (ADCY8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    117079299 (ADCY8)
Enzymes [BR:tfn01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     117079299 (ADCY8)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD
Other DBs
NCBI-GeneID: 117079299
NCBI-ProteinID: XP_033058911
LinkDB
Position
Unknown
AA seq 1251 aa
MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSSS
GSGGSGKASDPAGGGPNHHAPQLAGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASG
SGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRK
SEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHT
YLQYSGVVTWVAMTTQVLAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTS
LLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEAR
LRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADV
KGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAH
CCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKL
ESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPED
IVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHV
QSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAF
IVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINE
TYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTG
VLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNFNHSGEDFLGTKEA
SLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVA
RHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDE
LLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQPCEDKWEHLCALADFSLALTESIQEINKH
SFNNFELRIGEYHGSVVAGVIGAKKPQYDIWGKTVNLASXMDSTGVSGRIQVPEETYLIL
KDQGFAFDYRREIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAIVLGLG
QSLNRQRQKQLLNENNNTGIIKGHYNWRTLLSPSGTEPGAQAEGTDKPDLP
NT seq 3756 nt   +upstreamnt  +downstreamnt
atggagctctccgatgtgcgctgccttacaggcagcgaggaactctacaccatccacccg
acgcccccggccggcgacggcaggagcgcttcccggccgcagcggctgttgtggcagacg
gcggtgcggcacatcaccgagcagcgcttcattcacggccaccggggaggcagcagcagc
gggagtggaggctcgggcaaagcctcggaccctgcgggcggcggccccaaccaccacgcg
ccgcagctggcaggcgactcggcgctgcccctctactcgctgggcccgggagagcgagcg
cacagcacctgcggcaccaaagtcttcccggaacgcagcgggagcggcagtgccagcggc
agcggaggcgggggcgacctgggcttcctgcaccttgactgtgcccctagcaactcggat
ttctttctcaatgggggctatagctaccgaggggtcattttccccaccctgcgcaactcc
ttcaaatctcgggatctggaacgcctctaccagcgctatttcttgggccagaggcgcaaa
tcggaagtggtgatgaacgtgctggacgtgctgaccaaactcactctcttggtcctgcac
ttgagcctggcctcggcccccatggacccgctcaagggcatcctgctgggcttcttcacc
ggcattgaggtggtgatctgcgccctggtggtggtcaggaaggacaccacctcccacacg
tacctgcagtacagcggcgtggtcacctgggtggccatgaccacccaggtcctggcagca
ggcctcggctacgggctcctgggcgacggcataggctacgtgctcttcacgctcttcgcc
acctacagcatgctgccgctgccgctcacctgggccatcctggccggcctgggcacctcg
ctgctgcaggtcatcctccaagtggtcatcccccggctggcggtcatttccatcaaccag
gttgtggcccaggcagtgttattcatgtgtatgaacacagctggaatcttcatcagttac
ctgtcagaccgggcccagcgccaagctttcctggagactcggaggtgtgtggaggccagg
ctgcgcctggagacagagaaccaaagacaggagcggctcgtgctttctgtactcccccgg
tttgttgttctggaaatgatcaacgacatgaccaatgtggaagacgagcacctgcagcac
cagttccatcggatctacatccatcgctatgagaatgtcagtattctttttgcagatgtt
aaaggatttaccaacctctccacgaccttgtctgctcaggagctggtcaggatgctcaac
gagctctttgccagatttgatcgactggcccatgagcatcactgccttcgtattaaaatt
ctgggggactgctactactgcgtgtctggacttcctgagccccgccaggaccatgcccac
tgctgtgttgaaatgggtctcagcatgatcaaaaccatcaggtatgtgcggtcaagaaca
aaacacgatgttgacatgaggattggaatccactcaggctcggtgctgtgtggtgttctg
ggactaaggaagtggcagtttgatgtctggtcttgggatgtggacattgcaaacaaactc
gaatctggaggaatccccgggaggattcacatttccaaagccacgctagactgcctcaac
ggtgactataacgtggaagagggtcacggtaaagagaggaatgaattcctgaggaagcat
aatatcgagacttatttaattaagcagcctgaggacagcctgctgtccttgcctgaagat
atcgtcaaggagtcagtgagctcctcagaccggagaaacagtggggccacattcactgaa
ggatcctggagccctgagctaccctttgataatatcgtggggaaacaaaatactctggct
gccctaacaagaaattcaataaatctgcttccaaaccatcttgcacaagctttgcatgtc
cagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggc
gataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctg
gagcacaagtattctcaaatgagggatgaagtgttcaagtcaaacttggtctgtgcgttt
atcgttcttctatttatcacggcaatacaaagtttgcttccttcttcaagagtgatgcca
atgaccatccagttctccattctgattatgctgcactcggctctggtcctcatcaccaca
gcagaggattataagtgtttgcccctcatcctccggaaaacttgctgttggattaacgag
acctatttggcccggaacgtcatcatctttgcatccatcttgattaatttcctgggtgcc
atcttaaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttc
aattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcacgggg
gtgttggccatggtgacctgtgcagttttcctccgtctaaactccgtcctgaagctggca
gtgctgctgatcatgatcgccatctatgccctgctcactgagaccatctacgcaggcctc
tttctgcgttatgataacttcaaccacagtggagaagatttcctggggaccaaggaggcg
tcgctgctgctgatggccatgttcctcctggctgtgttctaccatggacagcagctggag
tacacagcccgcctggatttcctttggcgagtgcaggccaaagaagagatcaatgaaatg
aaggagctgagggaacacaatgagaacatgctccggaatatcttacccagccacgtggcc
cgccatttcctagagaaggaccgagacaatgaggagctgtattctcaatcctatgatgct
gttggggtgatgtttgcctccatcccaggatttgcggacttttactctcagactgaaatg
aataaccagggagtggaatgcctgcgcttgctgaatgagatcattgctgacttcgatgag
ttgcttggtgaagaccgatttcaagacattgaaaagattaagaccattggcagcacctac
atggccgtgtcaggcctgtcacctgaaaaacagccatgtgaagacaagtgggaacatttg
tgtgctctggctgacttctcactcgccctgacagaaagcatacaggagatcaacaagcat
tcattcaacaattttgaactccggattggtgagtaccatggctcagtggtagctggcgtt
atcggcgctaagaaaccacagtatgacatttggggcaaaactgtgaacttggcaagctga
atggacagcacaggggttagtggccggatccaagtcccagaggagacctatctcatcctg
aaggaccagggctttgcctttgattaccgaagggagatctatgtgaagggcatcagtgaa
caggaaggaaaaatcaaaacgtactttctcctgggaagagtccaacccaacccattcatc
ttgcccccgagaagactgcctgggcagtactccctggctgcgattgtcctgggacttggc
cagtccctcaataggcaaaggcagaagcaactactcaatgagaacaacaacacgggaatc
atcaagggtcattataactggcggactttgttgtcacccagcgggacggagcctggagcc
caagctgaaggcaccgacaaacctgatttgccataa

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