Trachypithecus francoisi (Francois's langur): 117089769
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Entry
117089769 CDS
T07225
Symbol
MDM2
Name
(RefSeq) E3 ubiquitin-protein ligase Mdm2 isoform X1
KO
K06643
E3 ubiquitin-protein ligase Mdm2 [EC:
2.3.2.27
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn01522
Endocrine resistance
tfn01524
Platinum drug resistance
tfn04068
FoxO signaling pathway
tfn04110
Cell cycle
tfn04115
p53 signaling pathway
tfn04120
Ubiquitin mediated proteolysis
tfn04144
Endocytosis
tfn04151
PI3K-Akt signaling pathway
tfn04218
Cellular senescence
tfn04625
C-type lectin receptor signaling pathway
tfn04919
Thyroid hormone signaling pathway
tfn05163
Human cytomegalovirus infection
tfn05165
Human papillomavirus infection
tfn05169
Epstein-Barr virus infection
tfn05200
Pathways in cancer
tfn05202
Transcriptional misregulation in cancer
tfn05203
Viral carcinogenesis
tfn05205
Proteoglycans in cancer
tfn05206
MicroRNAs in cancer
tfn05214
Glioma
tfn05215
Prostate cancer
tfn05218
Melanoma
tfn05219
Bladder cancer
tfn05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
117089769 (MDM2)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
117089769 (MDM2)
04151 PI3K-Akt signaling pathway
117089769 (MDM2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
117089769 (MDM2)
09143 Cell growth and death
04110 Cell cycle
117089769 (MDM2)
04115 p53 signaling pathway
117089769 (MDM2)
04218 Cellular senescence
117089769 (MDM2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
117089769 (MDM2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
117089769 (MDM2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117089769 (MDM2)
05202 Transcriptional misregulation in cancer
117089769 (MDM2)
05206 MicroRNAs in cancer
117089769 (MDM2)
05205 Proteoglycans in cancer
117089769 (MDM2)
05203 Viral carcinogenesis
117089769 (MDM2)
09162 Cancer: specific types
05214 Glioma
117089769 (MDM2)
05220 Chronic myeloid leukemia
117089769 (MDM2)
05218 Melanoma
117089769 (MDM2)
05219 Bladder cancer
117089769 (MDM2)
05215 Prostate cancer
117089769 (MDM2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
117089769 (MDM2)
05169 Epstein-Barr virus infection
117089769 (MDM2)
05165 Human papillomavirus infection
117089769 (MDM2)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
117089769 (MDM2)
01522 Endocrine resistance
117089769 (MDM2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tfn04131
]
117089769 (MDM2)
04121 Ubiquitin system [BR:
tfn04121
]
117089769 (MDM2)
Enzymes [BR:
tfn01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
117089769 (MDM2)
Membrane trafficking [BR:
tfn04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
117089769 (MDM2)
Ubiquitin system [BR:
tfn04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
MDM2/MDM4 proteins
117089769 (MDM2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
zf-C3HC4_3
Zn_ribbon_RanBP
SWIB
zf-RING_2
zf-FPG_IleRS
Motif
Other DBs
NCBI-GeneID:
117089769
NCBI-ProteinID:
XP_033077213
LinkDB
All DBs
Position
Unknown
AA seq
607 aa
AA seq
DB search
MPGCAATPRALLSGGRGRAPRQGWLLVGRVRPCVSGKWSKKPSPRGGPDPSDRDPAAFAV
RSPVPPRISAFERPVPWPREWNGPRGPGRSASAGPVKETGESRGTPDSKRENPGWQMCNT
NMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK
RLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSE
NRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRH
KSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSISDQ
FSVEFEVESLDSEDYSLSEEAQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLADYWK
CTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKK
TIVNDSKESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEE
SVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQM
IVLTYFP
NT seq
1824 nt
NT seq
+upstream
nt +downstream
nt
atgcccggatgcgccgcgacaccccgcgcgctcctctccggcggtagggggcgcgcaccg
cggcaaggttggctgcttgtgggccgtgtccggccctgtgtgtcgggaaaatggagcaag
aagccgagcccgaggggcggccccgacccctctgaccgagatcctgctgctttcgcagtc
aggagccccgtccctccccggattagtgcattcgagcgcccagtgccctggccccgagag
tggaatggtccccgaggcccagggcgtagtgcttccgcgggccccgtgaaggaaactggg
gagtctcgagggacccccgactccaagcgcgaaaaccccggatggcagatgtgcaatacc
aacatgtctgtacctactgatggtgctgtaaccacctcacagattccagcttctgaacaa
gagaccctggttagaccaaagccattgcttttgaagttattaaagtctgttggtgcacaa
aaagacacttacactatgaaagaggttcttttttatcttggccagtatattatgactaaa
cgattatatgatgagaagcaacaacatattgtatattgttcaaatgatcttctaggagat
ttgtttggcgtgccaagcttctctgtgaaagagcacaggaaaatatataccatgatctac
agaaacttggtagtagtcaatcagcaggaatcatcagactcaggtacatctgtgagtgag
aacaggtgtcaccttgaaggtgggagtgatcaaaaggaccttgtgcaagagcttcaggaa
gagaaaccttcatcttcacatttggtttctagaccatctacctcatctagaaggagagcg
attagtgagacagaagaaaattcagatgaattatctggtgaacgacaaagaaaacgccac
aaatctgatagtatttccctttcctttgatgaaagcctggctctgtgtgtaataagggag
atatgttgtgaaagaagcagtagcagtgaatctacagggacgccatcgaatccggatctt
gatgctggtgtaagtgaacattcaggtgattggttggatcaggattcaatttcagatcag
tttagtgtagaatttgaagttgaatctctcgactcagaagattatagccttagtgaagaa
gcacaagaactctcagatgaagatgatgaggtatatcgagttactgtgtatcaggcaggg
gagagtgatacagattcatttgaagaagatcctgaaatttccttagctgactattggaaa
tgcacttcatgcaatgaaatgaatccccctcttccatcacattgcaacagatgttgggcc
cttcgtgagaattggcttcctgaagataaagggaaagataaaggggaaatctctgagaaa
gccaaactggaaaactcaacacaagctgaagagggctttgatgttcctgattgtaaaaaa
actatagtgaatgattccaaagagtcgtgtgttgaggaaaatgatgataaaatcacacaa
gcctcacaatcacaagaaagtgaggactattctcagccatcaacttctagtagcattatt
tatagcagccaagaagatgtgaaagagtttgaaagagaagaaacacaagacaaagaagaa
agtgtggaatctagtttgccccttaacgccattgaaccttgtgtgatttgtcagggtcga
cctaaaaatggttgcattgtccatggcaaaacaggacatcttatggcctgctttacatgt
gcaaagaagctaaagaaaaggaataagccctgcccagtgtgtagacaaccaattcaaatg
attgtgctaacttatttcccctag
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