KEGG   Thermobifida fusca: Tfu_1825
Entry
Tfu_1825          CDS       T00265                                 
Name
(GenBank) methionine synthase (B12-dependent)
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
tfu  Thermobifida fusca
Pathway
tfu00270  Cysteine and methionine metabolism
tfu00450  Selenocompound metabolism
tfu00670  One carbon pool by folate
tfu01100  Metabolic pathways
tfu01110  Biosynthesis of secondary metabolites
tfu01230  Biosynthesis of amino acids
tfu04980  Cobalamin transport and metabolism
tfu04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:tfu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Tfu_1825
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Tfu_1825
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Tfu_1825
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Tfu_1825
   04980 Cobalamin transport and metabolism
    Tfu_1825
Enzymes [BR:tfu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Tfu_1825
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding B12-binding_2 CdhD Tautomerase_2 DUF3197
Other DBs
NCBI-ProteinID: AAZ55858
UniProt: Q47NW1
LinkDB
Position
complement(2127006..2130482)
AA seq 1158 aa
MSARLSFREVLGSRVLVADGAMGTMLQTYDLSMDDFEGHEGCNEVLNITRPDVVREIHEA
YLQAGVDCVETNTFGANFGNLGEYGIAERTYELAEAGARLAREAADAYTTADHVRYVLGS
VGPGTKLPTLGHAPYAVLRDHYEQCARGLIDGGVDAIVIETCQDLLQAKAAIVGARRARK
AAGTDTPIIVQVTIETTGTMLVGSEIGAALTSLEPLGVDMIGLNCATGPAEMSEHLRYLS
HHSRIPLSCMPNAGLPELGADGAVYPLQPHELTEAHDTFIREFGLALVGGCCGTTPEHLA
QVVERVQGRGVPDRKPHVEPAAASIYQSVPFRQDTSYLAIGERTNANGSKAFREAMLAER
YDDCVEIARQQIRDGAHMLDLCVDYVGRDGVRDMRELASRLATASTLPLVLDSTEVAVLE
AGLEMLGGRAVLNSVNYEDGDGPDSRFAKVAALAVEHGAALMALTIDEQGQARTAERKVE
VAERLIRQLTTEYGIRKHDIIVDCLTFTIATGQEESRRDALETIEAIRELKRRHPDVQTT
LGVSNVSFGLNPAARIVLNSVFLHECVQAGLDSAIVHASKILPINRIPEEQRQVALDMIY
DRRTDDYDPLQRFLQLFEGVDAQAMRASREEELAALPLWERLERRIVDGEAAGMEADLDE
ALTQRSALDIINTTLLAGMKTVGDLFGSGQMQLPFVLKSAEVMKAAVAYLEPHMEKVDGD
LGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVINLGIKQPISAILEAAERHRADVIGM
SGLLVKSTVVMRENLEEMNARGVADRYPVLLGGAALTRSYVEQDLAEIFKGEVRYARDAF
EGLKLMDAIMAVKRGVKGAKLPPLRTRRVKRGAQLTVTEPEKMPTRSDVATDNPVPTPPF
WGDRICKGIPLADYAAFLDERATFMGQWGLRGSRGDGPTYEELVETEGRPRLRMWLDRIQ
TEGWLEPAVVYGYYRCYSEGNDLVVLGEDENELTRFTFPRQRRDRHLCLADFFRPKESGE
LDTVAFQVVTVGSTISKATAELFEKNAYRDYLELHGLSVQLTEALAEYWHTRVRAELGFA
GEDPDPADLDAYFKLGYRGARFSLGYGACPNLEDRAKIVALLRPERVGVTLSEEFQLVPE
QSTDAIVVHHPEAKYFNV
NT seq 3477 nt   +upstreamnt  +downstreamnt
atgagcgctcgactctccttccgtgaagtcctcggttcccgcgtcctcgtcgccgacggg
gcgatgggaacgatgcttcagacatacgacctgagcatggacgacttcgagggacacgag
gggtgtaacgaggtcctcaacatcacccggcccgacgtggtccgggagatccacgaggcc
tacctgcaggccggcgtcgactgtgtcgaaaccaacacgttcggcgcgaacttcggaaac
ctcggcgaatacggcatcgcggaacgcacctacgaactggctgaagccggtgcccgcctg
gcccgcgaagccgccgacgcgtacaccactgccgatcacgtccgctacgtcctcggctct
gtggggcccgggacgaagctgcccacccttggccacgccccgtacgctgtgctgcgcgac
cactacgaacagtgcgcacgcgggctcattgacggcggtgtcgacgcgatcgtgatcgaa
acctgccaggacttgctgcaggcgaaagccgcgatcgtgggggcacggcgggcccgcaag
gccgcgggtaccgacacgccgatcatcgtccaggtgacgattgaaaccacggggaccatg
ctggtgggctccgagatcggtgcggcactgacctcgctggaaccgctaggggtcgacatg
atcggcctcaactgcgctaccggtccagcagagatgagcgagcacctgcgctacctctcc
caccactcccgcatccccctctcctgcatgccgaacgcgggcctgcctgagctgggggcg
gacggggccgtctacccgctgcagccgcatgagctcaccgaagcacacgacacgttcatc
cgcgagtttggcctggccctggtgggcggctgctgcggcaccacccctgagcacctcgcc
caagtggtggagcgggtgcagggacgcggcgtgccggaccgcaaaccgcacgtcgaaccc
gccgccgcctctatctaccagagcgtcccgttccgccaggacaccagctacctggcgatc
ggggaacgcaccaacgccaacggctccaaggcgttccgcgaagccatgctcgcggaacgc
tacgacgactgtgtggagatcgcccgccagcagatccgcgacggcgcgcacatgctcgac
ctgtgcgtcgactatgtgggacgcgacggggtgcgcgatatgcgggagctggcttcccgg
ctggccaccgcctccacgctgccgctcgtactggactccaccgaagtagcggtactggaa
gctggactggagatgctgggcgggcgcgccgtgctcaactcggtcaactacgaggacggc
gacggccctgactcccggttcgccaaggtcgccgcgctggcggtggagcacggggcggcc
ctcatggcgctgaccatcgacgagcaggggcaggcgcggaccgcggaacggaaagtggag
gtcgccgagcggctcatccggcagctcaccaccgagtacggcatccgcaagcacgacatc
atcgtggactgcctgaccttcacgatcgcaaccggacaggaggagtcgcggcgcgacgct
ctggaaaccatcgaggcgatccgtgaactgaagcggcgccacccggacgtgcagaccacg
ctgggcgtgtccaacgtctccttcgggctcaacccggctgcccgcattgtgctcaactcg
gtgttcctccacgagtgcgtccaggccggcttggactccgcgatcgtgcacgcctccaag
atcctgccgatcaaccgcatccccgaggagcagcggcaggtggcgttggacatgatctac
gaccgccgcaccgatgactacgacccgctgcaacgcttcctgcagcttttcgaaggagtg
gacgcgcaggcgatgcgcgcctcgcgcgaggaagagctggccgcgctgccgctgtgggag
cgcctggagcgccgtatcgtcgacggggaagccgccggcatggaagcggacctggacgaa
gcgctcacccagcggtccgcgctggacatcatcaacaccacgctgctggcggggatgaag
accgtcggcgacctgttcggctccgggcagatgcagctcccgttcgtgctgaagtcggcc
gaggtgatgaaggccgccgtggcctatctggagccgcacatggagaaggtggacggcgac
ctcggcaaggggcggatcgtgctggccacggtcaagggcgacgtccacgacatcggcaag
aaccttgtggacatcatcctgtccaacaacggctacgaggtcatcaacctggggatcaag
cagcccatctccgcgattctggaggcggccgagcggcaccgcgccgacgtgatcggcatg
tccggcctgctggtgaagtccacggtggtgatgcgggagaacctggaggagatgaacgcc
cgcggggtcgctgaccgctacccggtcctgctgggcggtgccgcgttgacccgctcctat
gtggaacaggacctcgccgagattttcaaaggcgaggtgcgctatgcccgcgacgctttt
gaaggcttgaagctcatggacgccatcatggcggtcaaacgcggggtgaagggggctaag
ctgccgccgctgcgcacccgccgggtgaagcggggcgcacagcttaccgtcaccgagccg
gagaagatgccgacgcgcagcgacgtggccaccgacaacccggtgccgaccccgccgttc
tggggggaccgcatctgcaaggggattccgctcgccgactacgcggctttcctggatgag
cgcgccacgttcatgggccagtgggggctgcgcggctcccgcggcgacggccccacctac
gaggagctggtggagacggaggggcggccgcggctgcgcatgtggctggaccggatccag
accgaggggtggctggagccggcggtcgtctacggctactaccgctgctacagcgaaggc
aacgacctggtcgtcctcggtgaggacgaaaacgagctgacccggttcacgttcccgcgg
cagcgccgcgaccggcacctgtgcctggctgacttcttccgccccaaggagtccggggaa
ctggacacggtggcgttccaggtcgtcaccgtcggttcgacgatcagcaaggcgaccgcg
gagctgttcgagaagaacgcgtaccgggactacttggagctccacgggctgtccgtgcag
ttgacggaggcactcgcggagtactggcacacccgggtccgcgccgagctgggcttcgcc
ggggaggatcccgacccggccgatttggacgcctactttaagctcggctatcgaggcgcc
cgtttctccctggggtacggggcctgccccaacttggaggaccgcgccaagatcgtggcc
ctgctgcgtccggaacgggttggggtgacgttgtccgaggagttccagcttgttcccgaa
cagtccactgacgcgatcgttgtccatcaccccgaggcgaaatacttcaacgtatga

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