KEGG   Theropithecus gelada (gelada): 112606386
Entry
112606386         CDS       T08041                                 
Symbol
PAK1
Name
(RefSeq) serine/threonine-protein kinase PAK 1 isoform X1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge04010  MAPK signaling pathway
tge04012  ErbB signaling pathway
tge04014  Ras signaling pathway
tge04024  cAMP signaling pathway
tge04062  Chemokine signaling pathway
tge04360  Axon guidance
tge04392  Hippo signaling pathway - multiple species
tge04510  Focal adhesion
tge04625  C-type lectin receptor signaling pathway
tge04650  Natural killer cell mediated cytotoxicity
tge04660  T cell receptor signaling pathway
tge04666  Fc gamma R-mediated phagocytosis
tge04810  Regulation of actin cytoskeleton
tge05132  Salmonella infection
tge05170  Human immunodeficiency virus 1 infection
tge05205  Proteoglycans in cancer
tge05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:tge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112606386 (PAK1)
   04012 ErbB signaling pathway
    112606386 (PAK1)
   04014 Ras signaling pathway
    112606386 (PAK1)
   04392 Hippo signaling pathway - multiple species
    112606386 (PAK1)
   04024 cAMP signaling pathway
    112606386 (PAK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112606386 (PAK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112606386 (PAK1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    112606386 (PAK1)
   04650 Natural killer cell mediated cytotoxicity
    112606386 (PAK1)
   04660 T cell receptor signaling pathway
    112606386 (PAK1)
   04666 Fc gamma R-mediated phagocytosis
    112606386 (PAK1)
   04062 Chemokine signaling pathway
    112606386 (PAK1)
  09158 Development and regeneration
   04360 Axon guidance
    112606386 (PAK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    112606386 (PAK1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    112606386 (PAK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112606386 (PAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112606386 (PAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tge01001]
    112606386 (PAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tge04131]
    112606386 (PAK1)
   03036 Chromosome and associated proteins [BR:tge03036]
    112606386 (PAK1)
Enzymes [BR:tge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     112606386 (PAK1)
Protein kinases [BR:tge01001]
 Serine/threonine kinases: STE group
  STE20 family
   112606386 (PAK1)
Membrane trafficking [BR:tge04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    112606386 (PAK1)
 Endocytosis
  Macropinocytosis
   Kinases
    112606386 (PAK1)
Chromosome and associated proteins [BR:tge03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     112606386 (PAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT Kdo
Other DBs
NCBI-GeneID: 112606386
NCBI-ProteinID: XP_025212556
Ensembl: ENSTGEG00000001923
LinkDB
Position
14:complement(69293361..69441747)
AA seq 577 aa
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNALNVKAVSETPAVPPVSEDEDDD
DDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTSTRDVATSPISPTENNTTPPDALTRNTE
KQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQ
MNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC
MDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK
RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG
TPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQMRKLRFQVFSNFSMIAASIPEDC
QAPLQPHSTDCCRKGGNKEQSLKPHPPQPHCAKPSVR
NT seq 1734 nt   +upstreamnt  +downstreamnt
atgtcaaataacggcctagacattcaagacaaacccccagcccctccgatgagaaatacc
agcactatgattggagctggcagcaaagatgctggaaccctaaaccatggttctaaacct
ctgcctccaaacccagaggagaagaaaaagaaggaccgattttaccgatccatcttacct
ggagataaaacaaataaaaagaaagagaaagagcggccagagatttctctcccttcagat
tttgaacacacaattcatgttggttttgatgctgtcacaggggagtttacgggaatgcca
gagcagtgggcccgcttgcttcagacatcaaatatcactaagtcggagcagaagaaaaac
ccgcaggctgttctggatgtgttggagttttacaactcaaagaagacatccaacagccag
aaatacatgagctttacagataagtcagctgaggattataattcttctaacgccttgaat
gtgaaggctgtgtctgagactcctgcagtgccaccagtttcagaagatgaggatgatgat
gatgatgatgctaccccaccaccagtgattgctccacgcccagagcacacaaaatctgta
tacacacggtctgtgattgaaccacttcctgtcacttcaactcgggacgtggctacatct
cccatttcacctactgaaaataacaccactccaccagatgctttgacccggaatactgag
aagcagaagaagaagcctaaaatgtctgatgaggagatcttggagaaattacgaagcata
gtgagtgtgggcgatcctaagaagaaatatacacggtttgagaagattggacaaggtgct
tcaggcaccgtgtacactgcaatggatgtggccacaggacaggaggtggccattaagcag
atgaatcttcagcagcagcccaagaaagagctgattattaatgagatcctggtcatgagg
gaaaacaagaacccaaacattgtgaattacttggacagttacctcgtgggagatgagcta
tgggttgttatggaatacttggctggaggctccttgacagacgtggtgacagaaacatgc
atggatgaaggccagattgcagctgtgtgccgtgagtgtctgcaggctctggagtttttg
cattcgaaccaggtcattcacagagacatcaagagtgacaatattctgttgggaatggat
ggctctgtcaagctaactgattttggattctgtgcacagataaccccagagcagagcaaa
cggagcaccatggtgggaaccccatactggatggcaccagaggttgtgacacgaaaggcc
tatgggcccaaggttgacatctggtccctgggcatcatggccatcgaaatgattgaaggg
gagcctccatacctcaatgaaaaccctctgagagccttgtacctcattgccaccaatggg
accccagaacttcagaacccagagaagctgtcagctatcttccgggactttctgaaccgc
tgtcttgagatggatgtggagaagagaggttcagctaaagagctgctgcagatgaggaaa
ctgaggtttcaagtatttagtaacttttccatgatagcagcatcaattcctgaagattgc
caagcccctctccagcctcactccactgattgctgccgcaaaggaggcaacaaagaacaa
tcactaaaaccacacccaccccagcctcattgtgccaagccttctgtgagataa

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