Theropithecus gelada (gelada): 112609056
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Entry
112609056 CDS
T08041
Symbol
ALOX12
Name
(RefSeq) arachidonate 12-lipoxygenase, 12S-type
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00590
Arachidonic acid metabolism
tge01100
Metabolic pathways
tge01523
Antifolate resistance
tge04726
Serotonergic synapse
tge04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
112609056 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
112609056 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
112609056 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112609056 (ALOX12)
Enzymes [BR:
tge01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
112609056 (ALOX12)
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
112609056
NCBI-ProteinID:
XP_025217177
Ensembl:
ENSTGEG00000022045
UniProt:
A0A8D2FYQ7
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All DBs
Position
16:63244925..63260668
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AA seq
663 aa
AA seq
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MGRYRIRVATGAWLFSGSHNRVQLWLVGARGEAELELQLRPARGEEEEFDRDVAEDLGLL
QFVRLRKHHWLVDDAWFCDRITVQGPGACAEAAFPCYRWVQGEDILSLPEGTARLPGDNA
LDVFQKHREKELKDRQQIYCWATWKEGLPLTIAAERKDDLPPNMRFHEEKRLDFEWTLKA
GALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVHQCWQDDELFGYQFVNGANPML
LRRSTSLPSRLALPSGMEELRSQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
VMLKMEPNGKLLPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHQLQYH
LLNTHLVAEVIAVATMRCLPGLHPIFKLLIPHIRYTMEINTRARTQLISDGGIFDKAVST
GGGGHVQLLRRATAQLTYCSLCPPDDLADRGLLGLPGALYARDALRLWEIIARYVEGIVH
LFYQRDDVVRGDPELQAWCWEITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQH
AAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVQQACLQMAISWHLGRR
QPDMVPLGHHKEKYFSGPKPKAVLSQFQTDLENLEKEITARNEQLDLPYEYLKPSCIENS
VTI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatccgcgtggccaccggggcctggctcttctccgggtcgcacaac
cgcgtgcagctttggctggtcggggcgcgcggggaggcggagctggagctgcagctgcgg
ccggcgcggggagaggaggaggagtttgatcgtgacgttgcagaggacttggggctcctg
cagttcgtgaggctgcgcaaacaccactggctggtggacgacgcatggttctgcgaccgc
atcacggtgcagggccctggagcctgcgcggaggcggccttcccgtgctaccgctgggtg
cagggcgaggacatcctgagcctgcccgagggcaccgcccgcctgccaggagacaatgcc
ttggatgtgttccagaagcatcgagagaaggaactgaaagacagacagcagatctactgc
tgggccacctggaaggaagggttacccctgaccatcgctgcagagcgtaaggatgatcta
cctccaaatatgagattccatgaggagaagaggctggactttgaatggacactgaaggca
ggggctctggagatggccctcaaacgtgtttacaccctcctgagctcctggaactgccta
gaagactttgatcagatcttctggggccagaagagtgccctggctgagaaggttcaccag
tgctggcaggatgatgagctgttcggctaccagttcgtcaatggtgccaaccccatgctg
ttgagacgctcgacctctctgccctccaggctagcgctgccctcagggatggaggagctt
cggtctcaactggagaaagaacttcagaatggttccctgtttgaagctgacttcatcctt
ctggatggaattccagccaacgtgatccgaggagagaagcagtacctggctgcccccctc
gtcatgctgaagatggagcctaacgggaaactgctgcccatggtcatccagattcagcct
cccaaccccagctctccaaccccaacactgttcctgccctcggaccccccacttgcctgg
ctcctggcaaagtcctgggtccgaaattcagatttccaactgcaccagctccagtaccac
ctgctgaacacgcatctggtggctgaggtcatagctgtcgccaccatgcggtgcctccca
ggactgcaccccatcttcaagctcctgatcccccatatccgctacaccatggaaatcaac
acccgggcccggacccaactcatctcagatggaggaatttttgataaggcggtgagcaca
ggtggagggggccatgtgcagttgcttcgtcgggcgacggctcagctgacctactgctcc
ctctgtcctcctgacgacctggctgaccggggcctgctgggactcccaggtgctctctac
gcccgtgatgctttacggctctgggagatcattgccaggtatgtggaggggatcgtccac
ctcttctaccaaagggatgacgtagtgaggggggaccctgagctgcaggcctggtgttgg
gagatcacggaggtggggctgtgccaggcccaggaccgaggtttccctgtctccttccag
tcccagagtcaactctgccatttcctcaccatgtgcgtcttcacgtgcactgcccagcat
gccgccatcaaccagggccagctggactggtatgcctgggtccctaatgccccatgcaca
atgcggatgcctccacccaccaccaaggaagacgtgacaatggccacagtgatgggatca
ctacctgatgtccagcaggcctgtcttcaaatggccatctcatggcatctgggtcgccgc
cagccggacatggtgcctctggggcatcacaaagaaaaatatttctcaggccccaagccc
aaagctgtgctaagccaattccaaacagatttggaaaacctggaaaaggagattacagcc
cggaatgagcaacttgacttgccctatgaatacctgaagcccagctgcatagagaacagt
gtcaccatctga
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