Theropithecus gelada (gelada): 112610905 Help Entry 112610905         CDS       T08041                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism tge  Theropithecus gelada (gelada) Pathway tge04022   cGMP-PKG signaling pathway tge04068   FoxO signaling pathway tge04081   Hormone signaling tge04140   Autophagy - animal tge04152   AMPK signaling pathway tge04211   Longevity regulating pathway tge04213   Longevity regulating pathway - multiple species tge04910   Insulin signaling pathway tge04920   Adipocytokine signaling pathway tge04923   Regulation of lipolysis in adipocytes tge04930   Type II diabetes mellitus tge04931   Insulin resistance tge04932   Non-alcoholic fatty liver disease tge04935   Growth hormone synthesis, secretion and action tge05010   Alzheimer disease tge05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:tge00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     112610905 (IRS2)    04022 cGMP-PKG signaling pathway     112610905 (IRS2)    04152 AMPK signaling pathway     112610905 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     112610905 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     112610905 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112610905 (IRS2)    04923 Regulation of lipolysis in adipocytes     112610905 (IRS2)    04920 Adipocytokine signaling pathway     112610905 (IRS2)    04935 Growth hormone synthesis, secretion and action     112610905 (IRS2)   09149 Aging    04211 Longevity regulating pathway     112610905 (IRS2)    04213 Longevity regulating pathway - multiple species     112610905 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     112610905 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     112610905 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     112610905 (IRS2)    04932 Non-alcoholic fatty liver disease     112610905 (IRS2)    04931 Insulin resistance     112610905 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  112610905 NCBI-ProteinID:  XP_025220305 Ensembl:  ENSTGEG00000013686 UniProt:  A0A8D2F792 LinkDB All DBs Position 17:complement(48554690..48585774) Genome browser AA seq 1337 aa AA seqDB search MASPPRHGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDEA TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRAAAADAPPTAAPAASCSASLPGALGGSAGAAGA EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCR VRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLP AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGGEFY GYMTMDRPLSHCGRPYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAATVPPAGPAGPAPTSAAGRTF PASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLLNGDYLNVSPSDAVTTGTP PDFFSAALHAGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLE PQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPS LPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGS GTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGARSGHPVGSLDALLSPEASSPYPPLPPR PSASPSSSLQPPPPPPPPGELYRLPPASAAATVQGPGAASSSDTGDNGDYTEMAFGVAAT PPQPIAAPAKPEAVRVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQG GRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGGVPGGGDEPPT SPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRESSAGFQNGLNYIAIDVREEP GLPPQPQPQPQSPLPQPGDKNSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTYA SIDFLSHHLKEATIVKE NT seq 4014 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgcggcacgggccgcccgggccggcgagcggagacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcacgggcggcgacgaggcg acggcgggaggggggtcggcgccgcagccgccgcggctcgagtactacgagagcgagaaa aagtggcggagcaaggcaggcgcgccgaagcgggtgatcgcgctcgactgctgcctgaac atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggccgccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc gacctggtcagcgagggccgcgcggccgccgcagacgcgccccccaccgccgcgcccgcc gcgtcctgcagcgcctccctgcccggcgccctgggcggctctgccggcgccgccggggcc gaggacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtg aacctgaagcccaagggtctgggccagagcaagaacctgacgggcgtgtaccgtctgtgc ctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctg cagctcatgaacatccgccgctgcggccactcggacagcttcttcttcatcgaggtgggc cgctcggccgtcacgggtcccggcgagctgtggatgcaggcggatgactcggtggtggcg cagaacatacacgagaccatcctggaggccatgaaggcgctcaaagagctcttcgagttc cggccacgcagcaagagccagtcgtcggggtcgtcggccacacaccctatcagcgtcccc ggcgcgcgccgccaccaccacctggtcaacctaccccccagccagacgggcttggtgcgc cgttcgcgcaccgacagcctggccgccaccccgccggcggccaagtgcagctcgtgccgg gtgcgcaccgccagcgagggcgacggcggcgcggcggcgggggcagcggccgcgggcgcc aggccagtgtcggtggctgggagccccctgagccccgggccggtgcgcgcgcccctgagc cgctcgcacaccctgagcggtggctgcggcggccgcgggagcaaggtggcgctgctgccg gcagggggcgcgctgcagcacagccgctccatgtccatgcctgtggcgcactcgccgccc gccgccaccagccccggctccctgtcgtccagcagcggccacggctcgggctcctacccg ccgccgccgggcccgcacccgcccctgccgcacccactgcaccacggccccggccagcgg ccctccagcggcagcgcctccgcctcgggctcccccagcgaccccggcttcatgtccctg gacgagtacggctccagccccggcgacctgcgcgccttctgcagccaccggagcaacacg cccgagtccatcgcggaaacgccccctgcgcgagacggcagcggcggcggtgagttctac gggtacatgaccatggacaggcccctgagccactgtggccgcccctaccgcagggtctcg ggagacgcggcccaggacctggaccgagggctgcgcaagaggacctactccctgaccacg ccggcccggcagcggccggtgccccagccctcctccgcctcgctggatgagtacaccctg atgcgggccaccttctccggcagcgcaggccgcctctgcccgtcctgccccgcgtcctct cccaaggtggcctaccacccctacccagaggactacggagatatcgagatcggctcccac aggagctccagcagcaacctgggtgcagacgacggctacatgcccatgacgcctggcgcg gccctcgcgggcagtgggagcggcagctgcaggagcgacgactacatgcccatgagccct gccagcgtgtccgcccccaagcagatcttgcagcccagggccgccgccgctgccgccgcc accgtgccccctgcggggcctgcagggccagcgcccacctctgcggcgggcaggacattc ccggcgagcgggggcggttacaaggccagctcgccggccgagagctctcccgaggacagc gggtacatgcgcatgtggtgcggctccaagctgtccatggagcacgcggacggcaagctg ctgctcaacggggactacctcaacgtgtcccccagcgacgcggtcaccaccggcaccccg cccgactttttctccgcagccctgcacgccggcggggagccgctcaggggcgttcctggc tgctgctacagctccttgcctcgctcctacaaggccccctacacctgcggtggggacagc gaccagtacgtgctcatgagctcccccgtggggcgcatcctggaggaggagcggctggag cctcaggccacgccagggcccagccaggcggccagcgccttcggggcaggccccacgcag ccccctcaccccgtagtgccttcgccggtgcgacccagcggcggccgccccgagggcttc ctgggccagcgcggccgggctgtgcggcccacgcgcctgtccctggaggggctgcccagc ctgcccagcatgcacgagtacccactgccgccagagcccaagagccccggcgagtacatc aacatcgactttggcgagcccggggcccgcctgtcgccgcccgcgcctcccctgctggcg tcggcggcctcgtcctcctcgctcttgtccgccagcagcccggcctcgtcgctgggctca ggcaccccgggcaccagcagcgacagccggcagcgctccccgctctctgactacatgaac ctggacttcagctcccccaagtctcccaagccgggcgcccggagcggccaccccgtgggc tccttggacgccctcctgtcccctgaggcctcctccccgtatccgccgctgcccccgcgt ccgtccgcatccccgtcgtcgtccctgcagccgccaccgccaccaccgccccccggggag ctgtaccgcttgccccctgcttcggccgctgccaccgtccagggcccaggcgccgcctcg tcctcggacaccggagacaatggtgactacaccgagatggctttcggtgtggccgccacc ccgccgcaacccatcgcggcccccgcgaagccagaagctgtccgcgtggccagcccgacg tcgggcgtgaagaggctgagcctcatggagcaggtgtcgggggtcgaggccttcctgcag gccagccagcccccggacccccaccgcggcgccaaggtcatccgcgcagacccacagggg ggccgccgccgccacagctccgagaccttctcctccaccacgacggtcacccccgtgtcc ccgtctttcgcccacaaccccaagcgccacaactcggcctccgtggaaaatgtgtctctc aggaaaagcagcgagggcggcgtgggcggcgtccctggagggggcgacgagccgcccacc tcccccagacagttgcagccggcgccccccttggcaccgcagggccggccttggaccccg ggtcagcccgggggcttggtcggttgtcctgggagcggtggatcaccaatgcgcagagag agctctgccggcttccagaatggtctcaactacatcgccatcgacgtgagggaggagccc gggctgccaccccagccgcagccgcagccgcagtcgccacttcctcagccgggagacaag aactcctggggtcggacccgaagcctcgggggtctcatcagcgctgtgggcgtcggcagc accggtggcgggtgcggggggccaggtcccggtgccctgccccctgccaacacctacgct agcattgacttcttgtcccaccacttgaaggaggccaccatcgtgaaagagtga

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