Theropithecus gelada (gelada): 112623422
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Entry
112623422 CDS
T08041
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge01524
Platinum drug resistance
tge04010
MAPK signaling pathway
tge04071
Sphingolipid signaling pathway
tge04141
Protein processing in endoplasmic reticulum
tge04210
Apoptosis
tge04530
Tight junction
tge04668
TNF signaling pathway
tge04714
Thermogenesis
tge04722
Neurotrophin signaling pathway
tge04932
Non-alcoholic fatty liver disease
tge04936
Alcoholic liver disease
tge05010
Alzheimer disease
tge05012
Parkinson disease
tge05014
Amyotrophic lateral sclerosis
tge05016
Huntington disease
tge05017
Spinocerebellar ataxia
tge05022
Pathways of neurodegeneration - multiple diseases
tge05208
Chemical carcinogenesis - reactive oxygen species
tge05417
Lipid and atherosclerosis
tge05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
112623422 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112623422 (MAP3K5)
04668 TNF signaling pathway
112623422 (MAP3K5)
04071 Sphingolipid signaling pathway
112623422 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
112623422 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
112623422 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
112623422 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
112623422 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
112623422 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
112623422 (MAP3K5)
05012 Parkinson disease
112623422 (MAP3K5)
05014 Amyotrophic lateral sclerosis
112623422 (MAP3K5)
05016 Huntington disease
112623422 (MAP3K5)
05017 Spinocerebellar ataxia
112623422 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
112623422 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112623422 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
112623422 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
112623422 (MAP3K5)
04932 Non-alcoholic fatty liver disease
112623422 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
112623422 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tge01001
]
112623422 (MAP3K5)
Enzymes [BR:
tge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
112623422 (MAP3K5)
Protein kinases [BR:
tge01001
]
Serine/threonine kinases: STE group
STE11 family
112623422 (MAP3K5)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
112623422
NCBI-ProteinID:
XP_025239623
Ensembl:
ENSTGEG00000016021
UniProt:
A0A8D2F7U0
LinkDB
All DBs
Position
4:complement(161290775..161533606)
Genome browser
AA seq
1374 aa
AA seq
DB search
MSTEAGEGITFSVPPFAPSGFCTIPEGGICRRGGAAAVGESEEHQLPPPPPGSFWNVESA
AAPGIGCSAATSASSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREAC
ETVGATLETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANN
IILYCDTNSDSLQSLKELICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQP
NFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIR
QRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALN
RRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFK
KAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGF
FLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVD
FWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIH
EWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRS
TEEGDCESDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQ
PLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTI
GFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFT
GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVH
PEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNE
YLRSISLPVPVLVEDTSSSSEYGSVSPDTELKADPFSFKTRAKSCGERDVKGIRTLFLGI
PDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGSEEP
KLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNK
VLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDVEDDHEE
QPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELV
RKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSPGTNTEDSELTDWLRVN
GADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQT
NT seq
4125 nt
NT seq
+upstream
nt +downstream
nt
atgagcacggaggcgggcgagggcatcactttctctgtgccacccttcgccccctcgggc
ttctgcaccatccccgagggcggcatctgcaggaggggaggagcggcggcggtgggcgag
agcgaggagcaccagctgccaccgccgccgccgggcagcttctggaacgtggagagcgcc
gccgccccaggcatcgggtgttccgcggccacctccgcgagcagtgccacccgaggccgg
ggcagctctgttggcgggggcagccgacggaccacggtggcatatgtgatcaacgaagcg
agccaggggcaactggtggtggccgagagcgaggccctgcagagcttgcgggaggcgtgc
gagacggtgggcgccaccctggaaaccctgcattttgggaaactcgactttggtgaaacc
accgtcctggaccgcttttacaatgcagatattgcggtggtggagatgagcgatgccttc
cggcaaccgtccttgttttaccaccttggggtgagagaaagtttcagcatggccaacaac
atcatcctctactgtgatactaactcggactctctgcagtcgctgaaggaactcatttgc
cagaagaatactatgtgcactgggaactacacctttgttccttatatgataacgccacat
aacaaggtctactgctgtgacagcagcttcatgaaggggttgacagagctcatgcaaccg
aacttcgagctgcttcttggacccatctgcttacctcttgtggatcgttttattcaactt
ttgaaggtggcacaagcaagttctagccagtatttccgggaatctatactcaatgatatc
aggaaagctcgtaatttatacactggtaaagaattggcagctgagttggcaagaattcgg
cagcgagtagataatatcgaagtcttgacagcagatattgtcataaatctgttactttcc
tacagagatatccaggactatgattctattgtgaagctggtggagactttagaaaaactg
ccaacctttgatttggcctcccatcaccatgtgaagtttcattatgcatttgcactgaat
aggagaaatctccctggagacagagcaaaagctcttgatattatgattcccatggtgcaa
agtgaaggacaagttgcttcagatatgtattgcctagttggtcgaatctacaaagatatg
tttttggactctaatttcacagacacggaaagcagagaccatggagcttcttggttcaaa
aaggcatttgaatctgagccaacactacagtcaggaattaattatgcggtcctcctcctg
gcagctgggcaccagtttgaatcttcctttgagctccggaaagttggggtgaagctaagt
agtcttcttggtaaaaagggaaacttggagaaactccagagctactgggaagttggattt
tttctgggggccagtgtcctagccaatgaccacatgagagtcattcaagcatctgaaaag
ctttttaaactgaagacaccagcgtggtacctcaagtctattgtagagacaattttgata
tataagcattttgtgaaactgaccacagaacaacctgtggccaagcaagaacttgtggac
ttttggatggatttcctggtcgaggccacaaagacagatgttactgtggttaggtttcca
gtattaatattagaaccaaccaaaatctatcaaccttcttatttgtctatcaacaatgaa
gttgaggaaaagacaatctctatttggcacgtgcttcctgatgacaagaaaggtatacat
gagtggaattttagtgcctcttctgtcaggggagtgagtatttctaaatttgaagaaaga
tgctgctttctttatgtgctccacaattctgatgatttccaaatctatttctgtacagaa
cttcattgtaaaaagttttttgagatggtgaacaccattaccgaagagaaggggagaagc
acagaggaaggagactgtgaaagtgactcgctggagtatgactatgaatatgatgaaaat
ggtgacagagtcgttttaggaaaaggcacttacgggatagtctacgcaggtcgggacttg
agcaaccaagtcagaattgctattaaggaaatcccagagagagacagcagatactctcag
cccctgcatgaagaaatagcattgcataagcacctgaagcacaaaaatattgtccagtat
ctgggctctttcagtgagaatggtttcattaaaatcttcatggagcaggtccctggagga
agtctttctgctctccttcgttccaaatggggtccattaaaagataatgagcaaacaatt
ggcttttatacaaagcaaatactggaaggattaaaatatctccatgacaatcagatagtt
caccgtgacataaagggtgacaatgtattgattaatacctacagtggtgttctcaagatc
tctgacttcgggacatcaaagaggcttgctggcataaacccctgtactgaaacttttact
ggtaccctccagtatatggcaccagaaataatagataaaggaccaagaggctatggaaaa
gcagcagacatctggtctctgggctgtacaatcatcgaaatggccacaggaaaaccccca
ttttatgaactgggagaaccacaagcagctatgttcaaggtgggaatgtttaaagtccac
cctgagatcccagaatccatgtctgcagaggccaaggcattcatcctgaaatgttttgaa
ccagaccctgacaagagagcctgtgctaacgacttgcttgttgatgagtttttaaaagtt
tcaagcaaaaagaaaaagacacaacctaagctttcagctctttcagctggatcaaatgaa
tacctcaggagtatatctttgccagtacctgtgctggtggaggacaccagcagcagcagt
gagtacggctcagtttcacccgacacggagttgaaagcggaccccttctctttcaaaaca
agagccaaatcctgcggagaaagagatgtcaagggaattcggacactctttttgggcatt
ccagatgagaattttgaagatcacagtgctcccccttcccctgaagaaaaagattctgga
ttcttcatgctgaggaaggacagtgagaggcgagccacccttcacaggatcctgacggaa
gaccaagacaaagttgtgagaaatctaatggaatctttagctcaggggtctgaagaaccg
aaactaaaatgggaacacatcacaaccctcattgcaagcctcagagaatttgtgagatcc
actgaccgaaaaatcatagccaccacattgtcaaagctgaaactggagctggactttgac
agccatggcattagccaagtccaggtggtgctctttggttttcaagatgctgtcaataaa
gttcttcggaatcataacatcaagccgcactggatgtttgccttagacagtatcatccgg
aaggcggtgcagacagccattaccatcctggttccagaactaaggccacatttcagcctt
gcatctgagagtgatactgctgatcaagaagacttggatgtagaagatgaccatgaggaa
cagccttcaaatcaaactgtccgaagacctcaggctgtcattgaagatgccgtggctacc
tcaggcgtgagcacgcttagttctactgtgtctcatgattcccagagtgctcaccggtca
ctgaatgtacagcttggaaggatgaaaatagaaaccaatagattactggaagaattggtt
cggaaagagaaagagttacaagcactccttcatcgagctattgaagaaaaagaccaagaa
attaaacacctgaagcttaagtcccaacccatagaaattcctgaactgcctgtatttcac
ctaaattctcctggcacaaatactgaagattctgagcttaccgactggctgagagtgaat
ggagcggatgaagacactataagccggtttttggctgaagattatacactattggatgtt
ctctactatgttacacgtgatgacttaaaatgcttgagactaaggggagggatgctgtgc
acactgtggaaggccatcattgactttcgaaacaaacagacttga
DBGET
integrated database retrieval system
