Theropithecus gelada (gelada): 112625956 Help Entry 112625956         CDS       T08041                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism tge  Theropithecus gelada (gelada) Pathway tge00230   Purine metabolism tge01100   Metabolic pathways tge01522   Endocrine resistance tge04015   Rap1 signaling pathway tge04020   Calcium signaling pathway tge04022   cGMP-PKG signaling pathway tge04024   cAMP signaling pathway tge04062   Chemokine signaling pathway tge04072   Phospholipase D signaling pathway tge04081   Hormone signaling tge04082   Neuroactive ligand signaling tge04114   Oocyte meiosis tge04211   Longevity regulating pathway tge04213   Longevity regulating pathway - multiple species tge04261   Adrenergic signaling in cardiomyocytes tge04270   Vascular smooth muscle contraction tge04371   Apelin signaling pathway tge04540   Gap junction tge04611   Platelet activation tge04713   Circadian entrainment tge04714   Thermogenesis tge04723   Retrograde endocannabinoid signaling tge04724   Glutamatergic synapse tge04725   Cholinergic synapse tge04727   GABAergic synapse tge04750   Inflammatory mediator regulation of TRP channels tge04911   Insulin secretion tge04912   GnRH signaling pathway tge04913   Ovarian steroidogenesis tge04914   Progesterone-mediated oocyte maturation tge04915   Estrogen signaling pathway tge04916   Melanogenesis tge04918   Thyroid hormone synthesis tge04921   Oxytocin signaling pathway tge04922   Glucagon signaling pathway tge04923   Regulation of lipolysis in adipocytes tge04925   Aldosterone synthesis and secretion tge04926   Relaxin signaling pathway tge04927   Cortisol synthesis and secretion tge04928   Parathyroid hormone synthesis, secretion and action tge04934   Cushing syndrome tge04935   Growth hormone synthesis, secretion and action tge04970   Salivary secretion tge04971   Gastric acid secretion tge04972   Pancreatic secretion tge04976   Bile secretion tge05032   Morphine addiction tge05163   Human cytomegalovirus infection tge05166   Human T-cell leukemia virus 1 infection tge05200   Pathways in cancer tge05207   Chemical carcinogenesis - receptor activation tge05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:tge00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     112625956 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     112625956 (ADCY2)    04371 Apelin signaling pathway     112625956 (ADCY2)    04020 Calcium signaling pathway     112625956 (ADCY2)    04072 Phospholipase D signaling pathway     112625956 (ADCY2)    04024 cAMP signaling pathway     112625956 (ADCY2)    04022 cGMP-PKG signaling pathway     112625956 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     112625956 (ADCY2)    04081 Hormone signaling     112625956 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     112625956 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     112625956 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112625956 (ADCY2)    04062 Chemokine signaling pathway     112625956 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     112625956 (ADCY2)    04922 Glucagon signaling pathway     112625956 (ADCY2)    04923 Regulation of lipolysis in adipocytes     112625956 (ADCY2)    04912 GnRH signaling pathway     112625956 (ADCY2)    04913 Ovarian steroidogenesis     112625956 (ADCY2)    04915 Estrogen signaling pathway     112625956 (ADCY2)    04914 Progesterone-mediated oocyte maturation     112625956 (ADCY2)    04921 Oxytocin signaling pathway     112625956 (ADCY2)    04926 Relaxin signaling pathway     112625956 (ADCY2)    04935 Growth hormone synthesis, secretion and action     112625956 (ADCY2)    04918 Thyroid hormone synthesis     112625956 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     112625956 (ADCY2)    04916 Melanogenesis     112625956 (ADCY2)    04925 Aldosterone synthesis and secretion     112625956 (ADCY2)    04927 Cortisol synthesis and secretion     112625956 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112625956 (ADCY2)    04270 Vascular smooth muscle contraction     112625956 (ADCY2)   09154 Digestive system    04970 Salivary secretion     112625956 (ADCY2)    04971 Gastric acid secretion     112625956 (ADCY2)    04972 Pancreatic secretion     112625956 (ADCY2)    04976 Bile secretion     112625956 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     112625956 (ADCY2)    04727 GABAergic synapse     112625956 (ADCY2)    04725 Cholinergic synapse     112625956 (ADCY2)    04723 Retrograde endocannabinoid signaling     112625956 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     112625956 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     112625956 (ADCY2)    04213 Longevity regulating pathway - multiple species     112625956 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     112625956 (ADCY2)    04714 Thermogenesis     112625956 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112625956 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     112625956 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112625956 (ADCY2)    05163 Human cytomegalovirus infection     112625956 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     112625956 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     112625956 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112625956 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     112625956 (ADCY2) Enzymes [BR:tge01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      112625956 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  112625956 NCBI-ProteinID:  XP_025243349 Ensembl:  ENSTGEG00000001315 UniProt:  A0A8D2E156 LinkDB All DBs Position 6:7027247..7450564 Genome browser AA seq 1091 aa AA seqDB search MWQQAMRRRRYLRDRAEEAAGGGDGLPRSRDWLYESYYCMSQQHPLIVFLLLIVMGACLA LLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICLVAM GYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSAT PGGKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQ ERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFT RLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVK MGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGG VPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPR HTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTL RTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKVLEKEYRATALPAF KYYVTCACLIFFCIFIVQILVLPKTSVLGISFGAAFLLLAFILFVCFAGQLLQCSKKASP LLMWLLKSSGIIANRPWPRISLTIITTAIILTMAVFNMFFLSDSEETIPPTANTTNTSFS ASNNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTILLHT HAHVLGDYSQVLFERPGIWKDLKTMGSVSLSIFFITLLVLGRQNEYYCRLDFLWKNKFKK EREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASIPDFKEFY TESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHA QEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDI WGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEM SRSLSQSNVAS NT seq 3276 nt NT seq  +upstreamnt  +downstreamnt atgtggcagcaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggaggcggcg ggcggcggagacgggctgccgcggtcccgggactggctctacgagtcctactactgcatg agccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggcgcctgcctcgcc ctgctcgccgtcttcttcgcgctcgggctggaagttgaagaccatgtggcgtttctaata acagttccgaccgccctggcgattttctttgcgatatttatcctggtctgcatagagtct gtgtttaagaagctgctgcgcctcttctcgttggtgatatggatatgccttgttgccatg ggatacctgttcatgtgttttggaggtaccgtctctccctgggaccaggtatcgttcttc ctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgcgagacgccatcatt gccagtgtcctcacctcctcctcccacaccatcgtgcttagcgtctgcctgtctgcaacg ccgggaggcaaggagcacctggtctggcagatcctggccaatgtgatcattttcatctgt gggaacctggcaggagcctaccataagcacctcatggaacttgctcttcagcaaacatat caggacacctgtaattgcatcaagtcccggatcaagttggaatttgaaaaacgtcaacag gagcggcttctgctctccctgctgccggcccacatcgccatggagatgaaagcggagatc atccagaggttgcagggccccaaggcaggccagatggagaacacaaataacttccacaac ctgtacgtgaagcggcataccaacgtgagcatcttatacgctgacattgttggctttacc cggctggcaagtgactgctccccaggagaactagttcacatgctgaatgagctcttcgga aagtttgatcaaattgcaaaggagaatgaatgcatgagaattaaaattttaggagactgc tactactgtgtatctggactccctatatctctccctaaccatgccaagaactgtgtgaaa atgggactggacatgtgtgaagccataaagaaagtgagggatgctactggagttgatatc aacatgcgtgtgggcgtgcattctgggaacgtcctgtgcggcgtgattggtctgcagaag tggcagtatgatgtgtggtcacatgacgtgaccttggccaaccacatggaagccggaggg gtccctggacgtgttcacatttcttccgtcaccctggagcacttgaatggcgcttataaa gtggaggagggagatggtgacattagggacccatatttaaaacagcacctggtgaaaacc tactttgtaatcaaccccaagggagaacgacggagcccccagcatctcttcagacctcgc cacaccctcgacggagccaaaatgagggcctcggtccgcatgacccggtacttggaatcc tggggggcggccaagccctttgcacacctacatcacagggacagcatgaccacagagaat ggcaagatcagcaccacggatgtgcccatgggtcagcataattttcaaaatcgcacctta agaaccaagtcacaaaagaaaagatttgaagaagaattgaatgaaaggatgattcaagca attgatgggattaatgcacaaaagcaatggctcaagtctgaagacattcagagaatctca ctgcttttctataacaaagtactagaaaaagagtaccgggccacagcactgccagcgttc aagtattacgtgacttgtgcctgtctcatattcttctgtatcttcattgtgcagattctc gtgctgccaaaaacgtccgtcctgggcatctcctttggggctgcgtttctcttgctggcc ttcatcctcttcgtctgctttgctggacagcttctgcaatgcagcaaaaaagcctctccc ctgctcatgtggcttttgaagtcctcgggcatcattgccaaccgcccctggccacggatc tctctcacgatcatcaccacagccatcattttaaccatggccgtgttcaacatgtttttc ctgagtgactcagaggaaacaatccctccaactgccaatacaacaaacacaagcttttca gcctcaaataatcaggcggcgattctgcgtgcgcaaaatttatttttcctcccgtacttt atctacagctgcattctgggactgatatcctgttctgtgttcctgcgggtgaactacgag ctgaagatgttgatcatgatggtggcgttggtgggctacaacaccatcctactccacacc cacgcccacgtcctgggcgactacagccaggtcttgtttgagagaccaggcatttggaaa gacctgaagaccatgggctctgtgtctctctctatattcttcatcacactgcttgttctg ggtagacagaatgaatattactgtaggttagacttcttatggaagaacaagttcaaaaaa gagcgggaggagatagagaccatggagaacctgaaccgtgtactgctggagaacgtgctt cccgcgcacgtcgctgagcacttcctggccaggagcctgaagaatgaggatctataccac cagtcctatgactgtgtctgcgtcatgtttgcctccattccggatttcaaagaattttat acagaatccgatgtgaacaaggagggcttggaatgccttcggctcctgaacgagatcatc gctgactttgatgatcttctttccaagccaaaattcagtggagttgaaaagattaagacc attggcagcacatacatggcagcaacaggtctgagcgctgtgcccagccaggagcacgcc caggagcccgagcggcagtacatgcacattggcaccatggtggagtttgcctttgccctg gtagcgaagctggatgccatcaacaagcactccttcaacgacttcaaattgcgagtaggt attaaccatggacctgtgatagctggtgtgattggagctcagaagccacaatatgatatc tggggcaacactgtcaatgtggccagtaggatggacagcaccggagtcctggacaaaata caggttacggaggagacaagcctcgtcctgcagaccctcggatacacatgcacctgtcga ggaataatcaacgtgaaaggaaagggggacctgaagacgtactttgtaaacacagaaatg tcaaggtccctttcccagagcaatgtggcgtcctga

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