Theropithecus gelada (gelada): 112626117
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Entry
112626117 CDS
T08041
Symbol
PDGFRB
Name
(RefSeq) platelet-derived growth factor receptor beta isoform X1
KO
K05089
platelet-derived growth factor receptor beta [EC:
2.7.10.1
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge01521
EGFR tyrosine kinase inhibitor resistance
tge04010
MAPK signaling pathway
tge04014
Ras signaling pathway
tge04015
Rap1 signaling pathway
tge04020
Calcium signaling pathway
tge04072
Phospholipase D signaling pathway
tge04151
PI3K-Akt signaling pathway
tge04510
Focal adhesion
tge04540
Gap junction
tge04630
JAK-STAT signaling pathway
tge04810
Regulation of actin cytoskeleton
tge05165
Human papillomavirus infection
tge05200
Pathways in cancer
tge05206
MicroRNAs in cancer
tge05214
Glioma
tge05215
Prostate cancer
tge05218
Melanoma
tge05230
Central carbon metabolism in cancer
tge05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112626117 (PDGFRB)
04014 Ras signaling pathway
112626117 (PDGFRB)
04015 Rap1 signaling pathway
112626117 (PDGFRB)
04630 JAK-STAT signaling pathway
112626117 (PDGFRB)
04020 Calcium signaling pathway
112626117 (PDGFRB)
04072 Phospholipase D signaling pathway
112626117 (PDGFRB)
04151 PI3K-Akt signaling pathway
112626117 (PDGFRB)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
112626117 (PDGFRB)
04540 Gap junction
112626117 (PDGFRB)
09142 Cell motility
04810 Regulation of actin cytoskeleton
112626117 (PDGFRB)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112626117 (PDGFRB)
05206 MicroRNAs in cancer
112626117 (PDGFRB)
05230 Central carbon metabolism in cancer
112626117 (PDGFRB)
05231 Choline metabolism in cancer
112626117 (PDGFRB)
09162 Cancer: specific types
05214 Glioma
112626117 (PDGFRB)
05218 Melanoma
112626117 (PDGFRB)
05215 Prostate cancer
112626117 (PDGFRB)
09172 Infectious disease: viral
05165 Human papillomavirus infection
112626117 (PDGFRB)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112626117 (PDGFRB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tge01001
]
112626117 (PDGFRB)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tge04090
]
112626117 (PDGFRB)
Enzymes [BR:
tge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112626117 (PDGFRB)
Protein kinases [BR:
tge01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
112626117 (PDGFRB)
CD molecules [BR:
tge04090
]
Proteins
112626117 (PDGFRB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
ig
Ig_3
I-set
Ig_2
V-set
C1-set
VEGFR-1-like_Ig-like
VEGFR1-3_N_Ig-like
TrmE_N
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
112626117
NCBI-ProteinID:
XP_025243724
Ensembl:
ENSTGEG00000002364
UniProt:
A0A8D2EAX9
LinkDB
All DBs
Position
6:complement(146578357..146620653)
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AA seq
1106 aa
AA seq
DB search
MRLPGAMPALALKGQLLLLPLLLLLEPQVSQGLVITPPGPELILNVSSTFVLTCSGSAPV
VWERMSQELPQEMAKAQDNTFSSVLTLTNLTGLDTGEYFCTYNDSRGLEPDERKRLYIFV
PDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDIALPVPYDHQRGFS
GIFEDRSYICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTVVRQGENITLMCIVIGN
EVVNFEWTYPRKESGRLVEPVTDFLLDMPYHIRSILHIPSAELEDSGTYTCNVTESVNDH
QDEKAINITVVESGYVRLLGEVGALQFAELHRSRTLQVVFEAYPPPTVLWFKDNRTLGDS
SAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVL
ELSESHPDSGEQTVRCRGRGMPQPNIIWSACRDLKRCPRELPPILLGNSSEEENQLETNV
TYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDMQEVIVVPHSLPFKAVVISAILA
LVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQL
VLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGP
HLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNAL
PVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYTAPYDNYVP
SAPERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLV
KICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLG
GTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLER
LLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDSSSVLYTAVQPNEGDND
YIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQEEPEPEPQLERQV
EPEPELEQLPDSGCPAPRAEAEDSFL
NT seq
3321 nt
NT seq
+upstream
nt +downstream
nt
atgcggcttccgggtgcgatgccagctctggccctcaaaggccagctgctgttgctgccc
ctgctgttactgctggaaccgcaggtctctcagggcctggtcatcacacccccggggcca
gagcttatcctcaatgtctccagcacctttgttctgacctgctcgggttcagctcccgtg
gtgtgggagcggatgtcccaggagctcccacaggaaatggccaaggcccaggacaatacc
ttctccagtgtgctgacactgaccaacctcactgggctagacacgggagaatacttttgc
acctacaatgactcccgtggactggagcctgatgagcggaaacggctctacatctttgtg
ccagatcccaccgtgggcttcctccctaatgacgccgaggaactattcatctttcttacg
gaaataactgagatcaccattccatgccgagtaacagacccacaactggtggtgacactg
cacgagaagaaaggggacattgcactgcctgtcccctacgatcaccagcgtggcttttct
ggtatctttgaggacagaagctacatctgcaaaaccaccattggggacagggaggtggat
tccgacgcctactatgtctacagactccaggtgtcatccatcaacgtctccgtgaatgca
gtgcagacggtggtccgccagggtgagaacattaccctcatgtgcattgtgattgggaat
gaggtggtcaacttcgagtggacgtacccccgcaaagaaagtgggcggctggtggagccg
gtgaccgacttcctcttggatatgccttaccacatccgctccatcctgcacatccccagt
gccgagttagaagactcggggacctacacctgcaatgtgacagagagtgtgaacgaccat
caggatgaaaaggccatcaacatcactgtggttgagagcggctacgtgcggctcctggga
gaggtgggagcactacaatttgctgagctgcaccggagccggacactgcaggtagtgttc
gaggcctacccaccgcccaccgtcctgtggttcaaagacaaccgcaccttgggcgactcc
agcgcaggcgagatcgccctgtccacgcgcaacgtgtcagagaccaggtatgtgtcagaa
ctgacactcgttcgggtgaaggtggcagaggctggccactacaccatgcgggccttccat
gaggacgctgaggtccagctctccttccagctacagatcaatgtccctgtccgcgtgctg
gagctaagtgagagccacccagacagcggggaacagacagtccgctgtcgtggccggggc
atgccccagccgaacatcatctggtctgcctgcagagatctcaaaaggtgtccacgcgag
ctgccgcccatcctgctggggaacagttctgaagaggaaaaccagctggagacgaacgtg
acgtactgggaggaggagcaggagtttgaggtggtgagcacactgcgtctgcagcacgtg
gatcggccactgtcggtgcgctgcacgctgcgcaacgctgtgggccaggacatgcaggag
gtcatcgtggtgccacactctttgcccttcaaggcagtggtgatctcagccatcctggcc
ctggtggtcctcaccatcatctcccttatcatcctcatcatgctttggcagaagaagcca
cgttacgagatccgatggaaggtgattgagtctgtgagctctgatggccatgagtacatc
tacgtggaccccatgcagctgccctatgactccacgtgggagctgccgcgggaccagctt
gtgctgggacgaaccctcggctctggggcctttgggcaggtggtggaggccacggctcat
ggcctgagtcattctcaggccacgatgaaagtggccgtcaagatgcttaaatccacagcc
cgcagcagtgagaagcaagccctcatgtcggagctgaagatcatgagtcaccttgggccc
cacctgaacgtggtcaacctgttgggggcctgcaccaaaggaggacccatctatatcatc
actgagtactgccgctacggagacctggtggactacctgcaccgcaacaagcacaccttc
ctgcagcaccattccgacaagcgccgcccgcccagcgcggagctctacagcaatgcgctg
cccgttgggctccccctgcccagccatgtgtccctgactggggagagcgacggtggctac
atggacatgagcaaggacgagtcggtggactacgtgcccatgctggacatgaaaggagat
gtcaaatatgccgacatcgagtcctccaactacacggccccctacgataactacgttccc
tctgcccctgagaggacctgtcgggcaactttaatcaatgagtctccggtgctaagctac
atggaccttgtgggcttcagctaccaggtggccaatggcatggagttcctggcctccaag
aactgcgtccaccgagacctggcggccaggaacgtgctcatctgcgagggcaagctggtc
aagatctgtgactttggcctggctcgagacatcatgcgggattcgaattacatctccaaa
ggcagtacctttttgcctttgaagtggatggctccagagagcatcttcaacagcctctac
accaccctgagcgacgtgtggtccttcgggatcctgctctgggagatcttcactttgggt
ggcaccccttacccagagctgcccatgaatgagcagttctacaatgccatcaaacggggt
taccgcatggcccagcctgcccacgcctccgacgagatctatgagatcatgcagaagtgc
tgggaagagaagtttgagattcggccccctttctcccagctggtgctgcttctcgagaga
ctgttgggcgaaggttacaaaaagaagtaccagcaggtggatgaggagtttctgaggagt
gaccacccagccatccttcggtcccaggcccgcttgcccgggttccatggcctccgatct
cccctggacagcagctccgtcctctacactgccgtgcagcccaatgagggtgacaacgac
tatatcatccccctgcctgaccccaaacccgaggttgctgacgaaggcccactggagggt
tcccccagcctagccagctccaccctgaatgaagtcaacacctcctcgaccatctcctgt
gacagccctctggagccccaggaggaaccagagccagagccccagcttgagcgccaggtg
gaaccagagccagagctggaacagctgccggattcagggtgccccgcgcctcgagcggaa
gcagaggacagcttcctgtag
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