Theropithecus gelada (gelada): 112631315
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Entry
112631315 CDS
T08041
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00562
Inositol phosphate metabolism
tge01100
Metabolic pathways
tge01521
EGFR tyrosine kinase inhibitor resistance
tge04068
FoxO signaling pathway
tge04070
Phosphatidylinositol signaling system
tge04071
Sphingolipid signaling pathway
tge04115
p53 signaling pathway
tge04140
Autophagy - animal
tge04150
mTOR signaling pathway
tge04151
PI3K-Akt signaling pathway
tge04218
Cellular senescence
tge04510
Focal adhesion
tge04931
Insulin resistance
tge05165
Human papillomavirus infection
tge05166
Human T-cell leukemia virus 1 infection
tge05200
Pathways in cancer
tge05206
MicroRNAs in cancer
tge05208
Chemical carcinogenesis - reactive oxygen species
tge05213
Endometrial cancer
tge05214
Glioma
tge05215
Prostate cancer
tge05218
Melanoma
tge05222
Small cell lung cancer
tge05224
Breast cancer
tge05225
Hepatocellular carcinoma
tge05230
Central carbon metabolism in cancer
tge05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
tge05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
112631315 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
112631315 (PTEN)
04070 Phosphatidylinositol signaling system
112631315 (PTEN)
04071 Sphingolipid signaling pathway
112631315 (PTEN)
04151 PI3K-Akt signaling pathway
112631315 (PTEN)
04150 mTOR signaling pathway
112631315 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112631315 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
112631315 (PTEN)
04218 Cellular senescence
112631315 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112631315 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112631315 (PTEN)
05206 MicroRNAs in cancer
112631315 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
112631315 (PTEN)
05230 Central carbon metabolism in cancer
112631315 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112631315 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112631315 (PTEN)
05214 Glioma
112631315 (PTEN)
05218 Melanoma
112631315 (PTEN)
05215 Prostate cancer
112631315 (PTEN)
05213 Endometrial cancer
112631315 (PTEN)
05224 Breast cancer
112631315 (PTEN)
05222 Small cell lung cancer
112631315 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
112631315 (PTEN)
05165 Human papillomavirus infection
112631315 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112631315 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
112631315 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112631315 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
tge01009
]
112631315 (PTEN)
Enzymes [BR:
tge01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
112631315 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
112631315 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
112631315 (PTEN)
Protein phosphatases and associated proteins [BR:
tge01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
112631315 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PTEN_C2
Tc-R-P
PTP-SAK
DSPc
PTP-NADK
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
112631315
NCBI-ProteinID:
XP_025252037
Ensembl:
ENSTGEG00000006716
UniProt:
A0A8D2END5
LinkDB
All DBs
Position
9:84358708..84469249
Genome browser
AA seq
403 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSY
LLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI
DSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEAS
SSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1212 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaaggtttttggattcaaag
cataaaaaccattacaagatatacaatctttgtgctgaaagacattatgacaccgccaaa
tttaattgcagagttgcacaatatccttttgaagaccataacccaccacagctagaactg
atcaaacccttttgtgaagatcttgaccaatggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagctggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcggggcaaatttttaaaggcacaagaggccctagatttctatggggaagtaaggacc
agagacaaaaagggagtaactattcccagtcagaggcgctatgtgtattattatagctac
ctgttaaagaatcacctggattatagaccagtggcactgttgtttcacaagatgatgttt
gaaactattccaatgttcagtggcggaacttgcaatcctcagtttgtggtctgccagcta
aaggtgaagatatattcctccaattcaggccccacacgacgggaagacaagttcatgtac
tttgagttccctcagccgttacctgtgtgtggtgatatcaaagtagagttcttccacaaa
cagaacaagatgctaaaaaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaggaaacctcagaaaaagtagaaaatggaagtctatgtgatcaagaaatt
gatagcatttgcagtatagagcgtgcagataatgacaaggaatatctagtacttacttta
acaaaaaatgatcttgacaaagcaaataaagacaaagccaaccgatacttttctccaaat
tttaaggtgaagctgtacttcacaaaaacagtagaggagccgtcaaatccagaggctagc
agttcaacttctgtaacaccagatgttagtgacaatgaacctgatcattatagatattct
gacaccactgactctgatccagagaatgaaccttttgatgaagatcagcatacacaaatt
acaaaagtctga
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