KEGG   Theropithecus gelada (gelada): 112634274
Entry
112634274         CDS       T08041                                 
Symbol
MDM2
Name
(RefSeq) E3 ubiquitin-protein ligase Mdm2 isoform X1
  KO
K06643  E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge01522  Endocrine resistance
tge01524  Platinum drug resistance
tge04068  FoxO signaling pathway
tge04110  Cell cycle
tge04115  p53 signaling pathway
tge04120  Ubiquitin mediated proteolysis
tge04144  Endocytosis
tge04151  PI3K-Akt signaling pathway
tge04218  Cellular senescence
tge04625  C-type lectin receptor signaling pathway
tge04919  Thyroid hormone signaling pathway
tge05163  Human cytomegalovirus infection
tge05165  Human papillomavirus infection
tge05169  Epstein-Barr virus infection
tge05200  Pathways in cancer
tge05202  Transcriptional misregulation in cancer
tge05203  Viral carcinogenesis
tge05205  Proteoglycans in cancer
tge05206  MicroRNAs in cancer
tge05214  Glioma
tge05215  Prostate cancer
tge05218  Melanoma
tge05219  Bladder cancer
tge05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:tge00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    112634274 (MDM2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    112634274 (MDM2)
   04151 PI3K-Akt signaling pathway
    112634274 (MDM2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    112634274 (MDM2)
  09143 Cell growth and death
   04110 Cell cycle
    112634274 (MDM2)
   04115 p53 signaling pathway
    112634274 (MDM2)
   04218 Cellular senescence
    112634274 (MDM2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    112634274 (MDM2)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    112634274 (MDM2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112634274 (MDM2)
   05202 Transcriptional misregulation in cancer
    112634274 (MDM2)
   05206 MicroRNAs in cancer
    112634274 (MDM2)
   05205 Proteoglycans in cancer
    112634274 (MDM2)
   05203 Viral carcinogenesis
    112634274 (MDM2)
  09162 Cancer: specific types
   05214 Glioma
    112634274 (MDM2)
   05220 Chronic myeloid leukemia
    112634274 (MDM2)
   05218 Melanoma
    112634274 (MDM2)
   05219 Bladder cancer
    112634274 (MDM2)
   05215 Prostate cancer
    112634274 (MDM2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    112634274 (MDM2)
   05169 Epstein-Barr virus infection
    112634274 (MDM2)
   05165 Human papillomavirus infection
    112634274 (MDM2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    112634274 (MDM2)
   01522 Endocrine resistance
    112634274 (MDM2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tge04131]
    112634274 (MDM2)
   04121 Ubiquitin system [BR:tge04121]
    112634274 (MDM2)
Enzymes [BR:tge01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     112634274 (MDM2)
Membrane trafficking [BR:tge04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    112634274 (MDM2)
Ubiquitin system [BR:tge04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   MDM2/MDM4 proteins
    112634274 (MDM2)
SSDB
Motif
Pfam: zf-C3HC4_3 Zn_ribbon_RanBP SWIB zf-RING_2 zf-FPG_IleRS DUF7130
Other DBs
NCBI-GeneID: 112634274
NCBI-ProteinID: XP_025257267
Ensembl: ENSTGEG00000022571
UniProt: A0A8D2K6W8
LinkDB
Position
11:27808080..27841491
AA seq 497 aa
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE
LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD
WLDQDSVSDQFSVEFEVESLDSEDYSLSEEAQELSDEDDEVYRVTVYQAGESDTDSFEED
PEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE
EGFDVPDCKKTIVNDSKESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEF
EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP
CPVCRQPIQMIVLTYFP
NT seq 1494 nt   +upstreamnt  +downstreamnt
atggtgaggagcaggcaaatgtgcaataccaacatgtctgtacctactgatggtgctgta
accacctcacagattccagcttctgaacaagagaccctggttagaccaaagccattgctt
ttgaagttattaaagtctgttggtgcacaaaaagacacttatactatgaaagaggttctt
ttttatcttggccagtatattatgactaaacgattatatgatgagaagcaacaacatatt
gtatattgttcaaatgatcttctaggagatttgtttggtgtgccaagcttctctgtgaaa
gagcacaggaaaatatataccatgatctacagaaacttggtagtagtcaatcagcaggaa
tcatcagactcaggtacatctgtgagtgagaacaggtgtcaccttgaaggtgggagtgat
caaaaggaccttgtgcaagagcttcaggaagagaaaccttcgtcttcacatttggtttct
agaccatctacctcatctagaaggagagcgattagtgagacagaagaaaattcagatgaa
ttatctggtgaacgacaaagaaaacgccacaaatctgatagtatttccctttcctttgat
gaaagcctggctctgtgtgtaataagggagatatgttgtgaaagaagcagtagcagtgaa
tctacagggacgccgtcgaatccggatcttgatgctggtgtaagtgaacattcaggtgat
tggttggatcaggattcagtttcagatcagtttagtgtagaatttgaagttgaatctctc
gactcagaagattatagccttagtgaagaagcacaagaactctcagatgaagatgatgag
gtatatcgagttactgtgtatcaggcaggggagagtgatacagattcatttgaagaagat
cctgaaatttccttagctgactattggaaatgcacttcatgcaatgaaatgaatccccct
cttccatcacattgcaacagatgttgggcccttcgtgagaattggcttcctgaagataaa
gggaaagataaaggggaaatctctgagaaagccaaactggaaaactcaacacaagctgaa
gagggctttgatgttcctgattgtaaaaaaactatagtgaatgattccaaagagtcgtgt
gttgaggaaaatgatgataaaatcacacaagcctcacaatcacaagaaagtgaggactat
tctcagccatcaacttctagtagcattatttatagcagccaagaagacgtgaaagagttt
gaaagggaagaaacacaagacaaagaagaaagtgtggaatctagtttgccccttaatgcc
attgaaccttgtgtgatttgtcagggtcgacctaaaaatggttgcattgtccatggcaaa
acaggacatcttatggcctgctttacatgtgcaaagaagctaaagaaaaggaataagccc
tgcccagtgtgtagacaaccaattcaaatgattgtgctaacttatttcccctag

DBGET integrated database retrieval system