Theropithecus gelada (gelada): 112636264 Help Entry 112636264         CDS       T08041                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism tge  Theropithecus gelada (gelada) Pathway tge01524   Platinum drug resistance tge04115   p53 signaling pathway tge04210   Apoptosis tge04215   Apoptosis - multiple species tge04217   Necroptosis tge04620   Toll-like receptor signaling pathway tge04621   NOD-like receptor signaling pathway tge04622   RIG-I-like receptor signaling pathway tge04623   Cytosolic DNA-sensing pathway tge04625   C-type lectin receptor signaling pathway tge04657   IL-17 signaling pathway tge04668   TNF signaling pathway tge04932   Non-alcoholic fatty liver disease tge04936   Alcoholic liver disease tge05010   Alzheimer disease tge05016   Huntington disease tge05022   Pathways of neurodegeneration - multiple diseases tge05132   Salmonella infection tge05134   Legionellosis tge05142   Chagas disease tge05145   Toxoplasmosis tge05152   Tuberculosis tge05160   Hepatitis C tge05161   Hepatitis B tge05162   Measles tge05163   Human cytomegalovirus infection tge05164   Influenza A tge05165   Human papillomavirus infection tge05167   Kaposi sarcoma-associated herpesvirus infection tge05168   Herpes simplex virus 1 infection tge05169   Epstein-Barr virus infection tge05170   Human immunodeficiency virus 1 infection tge05200   Pathways in cancer tge05203   Viral carcinogenesis tge05416   Viral myocarditis tge05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:tge00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     112636264 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     112636264 (CASP8)    04215 Apoptosis - multiple species     112636264 (CASP8)    04217 Necroptosis     112636264 (CASP8)    04115 p53 signaling pathway     112636264 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     112636264 (CASP8)    04621 NOD-like receptor signaling pathway     112636264 (CASP8)    04622 RIG-I-like receptor signaling pathway     112636264 (CASP8)    04623 Cytosolic DNA-sensing pathway     112636264 (CASP8)    04625 C-type lectin receptor signaling pathway     112636264 (CASP8)    04657 IL-17 signaling pathway     112636264 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112636264 (CASP8)    05203 Viral carcinogenesis     112636264 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     112636264 (CASP8)    05161 Hepatitis B     112636264 (CASP8)    05160 Hepatitis C     112636264 (CASP8)    05164 Influenza A     112636264 (CASP8)    05162 Measles     112636264 (CASP8)    05168 Herpes simplex virus 1 infection     112636264 (CASP8)    05163 Human cytomegalovirus infection     112636264 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     112636264 (CASP8)    05169 Epstein-Barr virus infection     112636264 (CASP8)    05165 Human papillomavirus infection     112636264 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     112636264 (CASP8)    05134 Legionellosis     112636264 (CASP8)    05152 Tuberculosis     112636264 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     112636264 (CASP8)    05142 Chagas disease     112636264 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     112636264 (CASP8)    05016 Huntington disease     112636264 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     112636264 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     112636264 (CASP8)    05416 Viral myocarditis     112636264 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     112636264 (CASP8)    04932 Non-alcoholic fatty liver disease     112636264 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     112636264 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:tge01002]     112636264 (CASP8) Enzymes [BR:tge01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      112636264 (CASP8) Peptidases and inhibitors [BR:tge01002]  Cysteine peptidases   Family C14: caspase family    112636264 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  112636264 NCBI-ProteinID:  XP_025260630 Ensembl:  ENSTGEG00000029115 LinkDB All DBs Position 12:77829663..77888983 Genome browser AA seq 496 aa AA seqDB search MVPGKGGADYILLPFEEMDFNRNLYDIGEQLDSEELASLKFLSLDCIPQRKQEPIKDALM LFQRLQEKRMLEENNLSFLKELLFRINRLDLLTTYLNTRKEEMERELQAPGRAQISAYRV MLYQISEEVGRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRV CAQVNKSLLKIINDYEEFSRERTRSLEGSPEEGSNGEELCGLMTISDSPREQDSESQTLD KVYQMKSKPRGYCLIINNYDFTKAREKVPKLYSIRDRNGTHLDAEALTATFEELHFEIQH HNDCTVEKIYKILKTYQLMDHSNKDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGL KCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGM ATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQM PQPTFTLRKKLVFPSD NT seq 1491 nt NT seq  +upstreamnt  +downstreamnt atggtgccaggaaagggtggagcggattatattctgctgccttttgaagagatggacttc aacagaaatctttatgatattggggaacaactggacagtgaagagctggcctccctcaag ttcctgagcctggactgcattccacaaaggaagcaagaacccatcaaggatgccttgatg ttattccagagactccaggaaaagagaatgttggaggaaaacaatctgtccttcctgaag gagctgctcttccgaattaatagactggatttgctcactacttacctaaacactagaaag gaggagatggaaagggaacttcaggcaccaggcagggctcagatttctgcctacagggtc atgctctatcagatttcagaagaggtgggcagatcagaattgaggtcttttaagtttctt ctgcaagaggagatctccaaatgcaaactggatgatgacatgaacctgctggatattttc atagagatggagaagagggtcatcctgggagaaggcaagttggacatcctgaagagagtc tgtgcccaagtcaacaagagcctgctgaagataatcaatgactatgaagaattcagcaga gagagaacaaggagccttgaaggaagtcctgaggaaggttcaaatggggaggagttgtgt gggctaatgacaatctcggactctccaagagaacaggatagtgaatcacagactttggac aaagtttaccaaatgaaaagcaaacctcggggatactgtctaatcatcaacaattacgat tttacgaaagcacgggagaaagtgcccaaactttacagcattagggacaggaatggaaca cacttggatgcagaggctttgaccgcgacctttgaagagcttcattttgagatccagcac cacaatgactgcacagtagagaaaatctataagattttgaaaacctaccaactcatggac cacagtaacaaggattgcttcatctgctgtatcctctcccatggagacaagggcatcatc tatggcactgatggacaggaggcccccatctatgagctgacatctcagttcactggtttg aagtgcccttcccttgctggaaaacccaaagtgttttttattcaggcttgtcagggggat aactaccagaaaggtatacctgttgagactgattcagaggagcaaccctatttggaaatg gatttatcatcacctcaaacgagatatatcccggatgaggctgactttctgctggggatg gccactgtgaataactgtgtttcctaccgaaaccctgcagagggaacctggtacatccag tcactttgccagagcctgagagaacgatgtcctcgaggcgatgatattctcaccatcctg actgaagtgaactatgaagtaagcaacaaggatgacaagaaaaacatggggaaacagatg ccacagccaactttcacactaaggaaaaaacttgtcttcccttctgattga

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