KEGG   Thermoflavifilum sp.: IMW88_05140
Entry
IMW88_05140       CDS       T09844                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
theo  Thermoflavifilum sp.
Pathway
theo03030  DNA replication
theo03410  Base excision repair
theo03420  Nucleotide excision repair
theo03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:theo00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    IMW88_05140 (ligA)
   03410 Base excision repair
    IMW88_05140 (ligA)
   03420 Nucleotide excision repair
    IMW88_05140 (ligA)
   03430 Mismatch repair
    IMW88_05140 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:theo03032]
    IMW88_05140 (ligA)
   03400 DNA repair and recombination proteins [BR:theo03400]
    IMW88_05140 (ligA)
Enzymes [BR:theo01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     IMW88_05140 (ligA)
DNA replication proteins [BR:theo03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     IMW88_05140 (ligA)
DNA repair and recombination proteins [BR:theo03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     IMW88_05140 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     IMW88_05140 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     IMW88_05140 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      IMW88_05140 (ligA)
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 HHH_5 DNA_ligase_ZBD BRCT HHH PTCB-BRCT BRCT_2 Auto_anti-p27 DZR_2
Other DBs
NCBI-ProteinID: QOR76918
UniProt: A0A7M1TAJ9
LinkDB
Position
complement(1239216..1241318)
AA seq 700 aa
MYAPEEEKQLSRLLQDLLKRNYDHEAPAEQVKRLRQALRYAEWRYYVQDNPVISDGEYDA
LFHRLKQLETQHPELITPDSPTQRIASGLTENFPTVAHLTPMLSLDNSYNAADLRDWDRR
VKELAGISRVDYCIEPKYDGASISLIYENNILWRGATRGDGIRGDEITTNIKQIKAIPLS
ADFAALGIRRVEIRGEILMHKETFKALNQQRLAENLPPFANPRNATSGSLRMIDPREVAR
RKLQAVLYQISFVEMAHHQPLPETLLSQSGVIKTLHQLGFPTPYGLMKVVHHIDEAIQYL
QEFEQLRDSLPYEIDGMVIKVDDIRLQEKIGATTHHPRWAIAYKFKARQATSVLRKVEFQ
VGRTGTITPVAKIDPVPIGGVTVSSISLFNEDVVREKDLRIGDTVLVERAGDVIPYIVKP
VVEMRTGQEKPIVFPTHCPVCGDPLVKPHGEAAWRCVNMNCEAQVLERLIHFVSKDAMDI
KSLGEANVRRFYELGLLRSIPDIYRLDYDKIRRLEGFGEKSVHNLQQAIEASKKQPLNRL
IFALGIRYVGETTARTLAQAIDYLPDLHHWTIEQLTQLPDIGPKVASSIYDFFHNSDNMH
MLEELEKLGVNMRNKPQQAMQAGKLAGKTFLFTGTLPHLKRQEAEALVEQHGGKIASSVS
RTLDYLVVGEDPGSKLEKARKIPSVQIIDESQFLKLIESA
NT seq 2103 nt   +upstreamnt  +downstreamnt
atgtatgcacctgaagaagaaaaacaactttcccgactcctgcaggatttattaaaaagg
aactacgatcatgaagcaccggccgaacaggtaaaacggctacgtcaggccctgcgctat
gccgagtggcgatactatgtacaggacaatcctgtgatcagcgatggggaatatgatgcc
ttatttcatcgactgaaacaactggaaacacaacacccggagctaattacgcccgattca
cccacccagcggattgccagcggtttgacggaaaatttccctacggtcgcccatctcacc
cctatgctttcgctggataactcctacaatgcggccgacctgcgcgattgggacaggcga
gtgaaggaactggctggtatttcccgggtggattactgcattgagccgaaatacgatggg
gccagcatttcattgatttatgaaaacaatatcctgtggcgcggcgccacacgcggcgat
ggcatccggggtgatgaaattaccaccaatatcaaacaaattaaagccatcccgctatca
gccgattttgctgcacttggcatccggagggtagaaatccgcggcgaaatcctgatgcat
aaagaaactttcaaagcgctcaaccagcaacgcctggccgaaaaccttccgcccttcgcc
aatccacgtaatgccacatcaggatccctgcgcatgatcgatccccgtgaggtagccaga
cgtaaactgcaggctgtgttgtaccagatcagtttcgtggaaatggcccatcaccaaccc
ctgcccgaaaccctgcttagccaatcgggtgttattaaaaccctgcaccaattaggtttt
cccacaccttacggtttgatgaaagtcgtacaccatatcgacgaggcgattcaataccta
caagaatttgaacaattacgcgattccctcccgtatgagatcgacggcatggtgattaaa
gtcgatgatatccgtcttcaagaaaaaataggcgccaccacgcatcacccacgctgggcc
attgcttataaattcaaagcccgccaggctacgagtgtgttgcgcaaagtggaatttcag
gtaggacgtaccggcaccatcaccccggtggctaaaattgatcctgttcccattggcgga
gttaccgtgagctccatttctttattcaatgaagatgtagtacgggaaaaggatctgcgt
atcggcgacactgtactggtggaacgtgccggcgatgtgataccttacatcgtgaaacct
gttgtggaaatgcgaactggccaggaaaaaccgattgtattccccacccattgtccggtg
tgtggcgacccgctggtgaaaccccacggtgaagccgcctggagatgtgtgaacatgaat
tgcgaggcgcaggtgctggaacgcctgatccattttgtaagcaaggacgctatggatatc
aaaagcctcggagaggccaacgtacgtcgattttacgagctgggattgttgcgcagcata
cccgatatctatcggctggattatgataaaatccgccggcttgaaggcttcggcgaaaaa
tctgtccacaaccttcagcaggccattgaggcttcaaaaaaacagcccttaaaccggctc
atctttgctctgggcattcgatatgtgggcgaaactaccgcccgcacactggctcaggct
attgactacctgccagatttgcaccactggaccattgaacaacttacccagcttcccgat
atcggtcccaaagtagccagcagcatttacgattttttccataacagcgacaatatgcac
atgctggaagaattggagaagctgggcgtgaatatgcgcaacaaacctcaacaggccatg
caggccggaaaattagctggcaaaacttttttgtttaccggtaccttgcctcatttgaaa
cgtcaggaagccgaggcgctcgtggagcaacacgggggtaaaatcgccagcagcgtgagt
cgcactctggattatctggtcgtgggtgaagaccccggctccaagctcgagaaagcccgg
aagataccctccgtacaaatcatcgatgaatctcaatttttaaaactgattgaatccgcc
tga

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