KEGG   Thermoanaerobacter sp. RKWS2: OEI98_000684
Entry
OEI98_000684      CDS       T10300                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
thez  Thermoanaerobacter sp. RKWS2
Pathway
thez03030  DNA replication
thez03410  Base excision repair
thez03420  Nucleotide excision repair
thez03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:thez00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    OEI98_000684 (ligA)
   03410 Base excision repair
    OEI98_000684 (ligA)
   03420 Nucleotide excision repair
    OEI98_000684 (ligA)
   03430 Mismatch repair
    OEI98_000684 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:thez03032]
    OEI98_000684 (ligA)
   03400 DNA repair and recombination proteins [BR:thez03400]
    OEI98_000684 (ligA)
Enzymes [BR:thez01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     OEI98_000684 (ligA)
DNA replication proteins [BR:thez03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     OEI98_000684 (ligA)
DNA repair and recombination proteins [BR:thez03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     OEI98_000684 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     OEI98_000684 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     OEI98_000684 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      OEI98_000684 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 Nlig-Ia DNA_ligase_ZBD HHH RNA_ligase PTCB-BRCT BRCT_2 HHH_8 HHH_3 CoA_binding_2 Cdd1 RNA_pol_A_CTD
Other DBs
NCBI-ProteinID: UZQ83597
LinkDB
Position
685150..687138
AA seq 662 aa
MEPKERIKELREKINYHNYRYYVLDQPEISDYEYDMLMRELIELEEKYPELKTPDSPSQR
VGGEPLKEFEPFTHVVPMLSLANAFSEGELRDFDRRVREAVGDVEYVVELKIDGLSVELI
YENGIFTVGSTRGDGIVGENVTQNLKTIKSIPLRLKDDVSLVVRGEVFMPRTSFEKLNEE
REKLGESLFANPRNAAAGSLRQLDPKVTAKRDLDIFIFNLQKIEGRKFKTHIETLEFLKE
QGFKVIPIHKKCSNIDEVIKEIEEIRNLRDKLPYDIDGAVVKVNELEKREILGQTAKDPR
WAIAFKYPAERKKTKVLDIIVQVGRTGALTPTAILEPVTISGSVVSRATLHNEDYIKEKD
IRIGDTVIVQKAGEIIPEVVEVVKEERTGQEREFVMPDRCPECGALAVRLPGEAIRRCTG
LNCPAQLLRGIIHFASKDAMDIEGLGPAIINQLLSKGLIHNIADLYYLKYEDLIQLERMG
DKSVKNLLNAIEESKTRDLDRLLFGLGINLIGSKAAQVIAEHFKTMDNIMKAKFEDFTQL
PDIGPKMARSIVSFFAEKQNVEIIEKLKKAGVNMKKLSKGKVSNIFEGKTFVLTGALESY
TREEATRMIEERGGKVTNSVSKKTDYVLVGKDPGSKLKKAQELGIKIIDEKQFEEMLKGE
NI
NT seq 1989 nt   +upstreamnt  +downstreamnt
atggagccaaaagaaaggataaaggaattgagagaaaaaataaattatcacaattacaga
tattacgttttggaccaaccagagatttcagactatgagtacgacatgctgatgagagaa
cttatagaattagaagaaaaatatccagagcttaaaactccagactctccatcccaaaga
gtaggtggggagcctttaaaagaatttgagccttttacccatgtagttccaatgttaagt
ttggctaatgctttttctgagggagaacttagagactttgacagaagagtaagagaggca
gtgggagatgtagagtacgtagtagaattaaaaattgacggtttatctgtggaactaatt
tatgaaaatggcatatttactgtaggttctacaagaggagacgggatcgtaggagaaaat
gtcacacaaaatttaaagactataaagtcaattcctttaaggcttaaggatgatgtgagc
cttgttgtaagaggagaggtcttcatgccccgcacttcttttgaaaaattaaatgaggag
agagaaaaattaggggaaagcctttttgcaaatcccagaaatgctgcagcaggttcttta
aggcaattagatcctaaagtgacggcgaaaagagatttagacatttttatttttaacctt
cagaagattgagggtagaaaatttaaaactcacatagagacattagaatttttgaaagaa
caaggatttaaagtaataccaattcataaaaaatgtagcaatatagatgaagtaataaaa
gaaatagaagagataagaaacttacgagataagctgccttacgacattgatggagcagtt
gtaaaagtaaatgaacttgaaaagagagaaattttaggacagactgcaaaagaccccaga
tgggctattgcttttaaatatcctgcagagaggaaaaagacaaaagtcttggatataata
gttcaagtaggaaggactggagctcttactcctacagctatattagagcctgtaactatt
tcaggttcagttgtgagccgagctacacttcataatgaagattacataaaagagaaagac
ataaggataggagatacggtaatagttcaaaaagcgggagaaatcattcctgaagtagta
gaagtggtaaaagaagagaggactggacaagaaagagagtttgtaatgccagatagatgc
cctgaatgcggtgctttagctgtgaggcttccgggggaggctataaggcgttgcacaggt
ctaaattgtcctgcacagcttctaagaggcattatccactttgcttcaaaagatgcaatg
gatatagaaggattggggccagctataataaatcagcttttgtcaaaaggtctaattcac
aacatagcagatttgtattatcttaaatacgaagatttaatacaattagaaagaatgggg
gacaaatctgttaaaaatttattaaatgctattgaagaaagcaaaacaagagatttagat
agattgctctttggcttgggtataaacttaataggcagtaaagctgcccaagtgattgct
gagcattttaagacaatggacaatatcatgaaggcaaaatttgaagactttacacagttg
cctgacataggacctaagatggcaagaagcatagtttccttttttgcagaaaaacaaaat
gtagagataattgaaaaacttaaaaaggctggagtaaacatgaaaaaactttcaaaagga
aaagtaagcaacatatttgaagggaaaacttttgttttgacaggagcgttggaaagttac
acgagagaagaagctaccagaatgattgaagaaagaggtggaaaagttacaaattcagta
agtaaaaaaacagactatgtattagtaggtaaagatcctggttctaaacttaaaaaagcc
caagaattaggaataaagataattgatgaaaaacaatttgaagaaatgctaaaaggtgaa
aatatttaa

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