Thalassospira sp. GO-4: M9H61_18975
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Entry
M9H61_18975 CDS
T10246
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
thgo Thalassospira sp. GO-4
Pathway
thgo00270
Cysteine and methionine metabolism
thgo00450
Selenocompound metabolism
thgo00670
One carbon pool by folate
thgo01100
Metabolic pathways
thgo01110
Biosynthesis of secondary metabolites
thgo01230
Biosynthesis of amino acids
thgo04980
Cobalamin transport and metabolism
thgo04981
Folate transport and metabolism
Module
thgo_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
thgo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
M9H61_18975 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
M9H61_18975 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
M9H61_18975 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
M9H61_18975 (metH)
04980 Cobalamin transport and metabolism
M9H61_18975 (metH)
Enzymes [BR:
thgo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
M9H61_18975 (metH)
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Motif
Pfam:
Met_synt_B12
Pterin_bind
B12-binding_2
B12-binding
DUF3786
Motif
Other DBs
NCBI-ProteinID:
URK17609
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Position
4166016..4168661
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AA seq
881 aa
AA seq
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MTDISRFINIGERTNVAGSLKFKKLIVDEDYDAALEIARQQVENGAQIIDINMDDAMLDA
ETAMVKFINLIAAEPDIARVPIMVDSSKWNVIEAGLKCLQGKGIVNSISLKEGEEPFIAQ
AKQLRRYGAAVVVMAFDEKGQADTVDRKFEICKRSYDVLVEKVGFPPEDIIFDPNIFAVA
TGIEEHDNYAVDFIEACKLIKKHLPYAKISGGVSNVSFSFRGNNPVREAMHSVFLYHAIQ
AGLDMGIVNAGQLVVYEEIPAELRERVEDVILNRRSDATDRLLEVAEKYKGTGGPEKKAD
LEWRKKPVNERLAHALVNGIAEFVEEDTEEARQQADKPLHVIEGPLMDGMNIVGDLFGAG
KMFLPQVVKSARVMKKAVAYLIPFIEEEKDGVRESNGKILLATVKGDVHDIGKNIVGVVL
QCNNFEVLDLGVMVPTQKIIETAKAEKVDMIGLSGLITPSLEEMTYVAAEMEREGLDIPL
LIGGATTSKVHTAVKIAPNYNKSVVYVIDASRAVGVASQLVSETHRERFAAEIRNEYLAM
AEKHAAQQLQKKRFALADARANKVQLDWDAYEVPVPAKPGITVFDDFDLEDLVARFDWKP
FFETWELHGRFPDILKDEKVGETARGLYDDAQEMLKRIVAEKWFKPRAVVGIWPANSVGD
DIEVTPAPDQNEPVMLHTLRQQMFRENNKRPNRALADYIAPKESGKTDYIGAFVVTAGPE
VEQIASKLEAEHDDYNAILVKALGDRFAEAFAERMHEKVRKELWAYAADENLGNDDLIAE
NYRGIRPAPGYPACPEHTEKRTLWSLLNAEENVGVSLTESCAMTPASSVSGFYFAHPEAK
YFGLGKIERDQVESYAERKGMTMAEAERWLAPNLNYDPRQS
NT seq
2646 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacatttccagatttatcaatattggtgaacgtaccaacgttgccggatcgctg
aaattcaaaaagctgatcgttgacgaagattacgatgcagcccttgagattgcccgccag
caggtcgaaaacggcgcgcaaatcatcgacatcaacatggatgatgcgatgcttgatgcc
gaaacggcgatggtcaagttcatcaacctgattgccgccgagcccgatattgcgcgcgtg
ccgatcatggtcgacagttccaaatggaacgtcatcgaggccggtcttaaatgtcttcag
ggcaaggggatcgtcaactcgatcagtctgaaagaaggcgaagaaccctttatcgcccag
gccaaacagttgcgccgttacggtgcagctgttgttgtcatggcctttgatgaaaaaggc
caggctgatacggtcgatcgcaagtttgaaatttgcaaacgcagctatgacgttctggtc
gaaaaagtcggcttcccgcccgaagatatcattttcgacccgaacatctttgcggtcgca
accgggatcgaagaacacgacaactatgcggtcgacttcatcgaagcctgcaagctgatc
aaaaaacacctgccctatgccaagatttccggcggtgtttcaaacgtgtccttctcgttc
cggggcaataacccggtgcgcgaagccatgcattcggtcttcctgtatcacgccatccag
gccggtcttgatatggggatcgtcaatgccgggcagctggtcgtttatgaagaaattccg
gcagaactgcgcgaacgcgttgaagacgtcattttgaaccgtcgttctgatgcgaccgac
cgtttgcttgaggttgccgaaaaatacaagggcaccggcggtccggaaaagaaagccgat
ctggaatggcgcaaaaagccggtcaatgaacgtctggcccatgcgctggtcaacggcatt
gccgaattcgtcgaggaagacaccgaagaagcccgccagcaggccgacaaaccgcttcat
gtcattgaagggccgctgatggatgggatgaacatcgtcggtgacctgtttggtgccggc
aagatgttcctgccccaagtggtgaaatccgcccgtgtgatgaaaaaggccgtcgcctat
ctgatcccgttcatcgaagaagaaaaagacggtgtgcgcgaaagcaacggcaagatcctt
ctggcgacggtaaagggcgatgtccatgacatcggcaagaacatcgttggtgtggttctg
caatgtaacaatttcgaggtcctcgaccttggtgtgatggttccgacccagaagatcatt
gaaactgccaaggccgaaaaggtcgacatgatcgggctttcgggcctgattacgccgtcg
cttgaagaaatgacctatgttgcggccgaaatggaacgcgaaggtctggatatcccgctt
ctgatcggcggggcgactacgtcaaaggtacataccgcagtcaagatcgcaccgaactat
aacaagtcggtcgtatacgtgattgatgcatcgcgtgcggtgggtgttgcaagccagctg
gtttcggaaacccatcgcgaacgatttgctgctgaaatccgcaatgaatatctggcgatg
gcggaaaaacacgccgcccagcaattgcagaaaaaacgcttcgcccttgccgatgcgcgt
gccaacaaggtgcagcttgactgggatgcctatgaggttccggttccggcaaagccgggg
atcaccgtgtttgatgactttgatcttgaagatctggtcgcgcgctttgactggaagccg
ttctttgaaacctgggaactgcatggtcgtttccccgacatcctcaaggatgaaaaagtc
ggcgaaactgcgcgcggtctttatgacgatgcgcaggaaatgttgaaacgcattgttgcg
gaaaaatggttcaagccgcgtgcggttgttggcatctggccggcaaactcggtcggtgat
gatatcgaagtcaccccggccccggatcagaatgagccggtcatgcttcataccctgcgc
cagcagatgttccgcgaaaacaacaaacgtccgaaccgggctttggccgattacatcgcg
ccgaaggaaagcggcaagaccgattatatcggtgcctttgttgtgacggcgggaccggaa
gtcgaacagatcgcctcaaagcttgaagccgagcatgacgattacaatgccattctggtc
aaggcgcttggtgatcgctttgccgaagcctttgccgagcgtatgcacgaaaaggtccgc
aaagagctttgggcctatgccgcagacgagaatctcggcaatgatgatctgattgcggaa
aattatcgcggtatccgtccggcaccgggttatcctgcgtgcccggaacataccgaaaaa
cgcaccctttggtcgcttttgaatgccgaggaaaatgtcggcgtttccctgaccgaaagc
tgtgcgatgaccccggcatcgtctgtcagcggtttctatttcgcccaccccgaagccaaa
tatttcggccttggcaagatcgaacgtgatcaggtcgaaagttatgccgaacgcaaaggc
atgaccatggccgaggcagaacgctggttggcaccaaacctgaattacgatccacgtcag
tcataa
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