KEGG   Thermotomaculum hydrothermale: TTHT_0332
Entry
TTHT_0332         CDS       T06993                                 
Name
(GenBank) hydrophobic/amphiphilic exporter-1, HAE1 family
  KO
K18138  multidrug efflux pump
Organism
thyd  Thermotomaculum hydrothermale
Pathway
thyd01501  beta-Lactam resistance
thyd01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:thyd00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    TTHT_0332
   01503 Cationic antimicrobial peptide (CAMP) resistance
    TTHT_0332
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:thyd02000]
    TTHT_0332
   01504 Antimicrobial resistance genes [BR:thyd01504]
    TTHT_0332
Transporters [BR:thyd02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   TTHT_0332
Antimicrobial resistance genes [BR:thyd01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    TTHT_0332
SSDB
Motif
Pfam: ACR_tran MMPL SecD_SecF_C HMA bVLRF1
Other DBs
NCBI-ProteinID: BBB31948
UniProt: A0A7R6PYH1
LinkDB
Position
complement(335730..338822)
AA seq 1030 aa
MRLPEFAVKKPVTVAMLFLGVFILGAVSVFFLSIDLLPKIDPPAISVITTYPGASATDVE
NDVTKILEDKLSSVNNLDKLLSTSKDNISIVTCKFDWGTNLDVAANDVRDKIDLAMKELP
KDIDRPMIFKFNSAMAPVLILSVNAKESYPQLARLAKDVIADNLKKVPGVGTVVIEGERD
RQINVFFDPEKLATYHLTTLQVIEAIKKQNIDLPLGSIKTGISEYMLRIPARFKSARELA
EMPVLVFNGKVVFLKDIAKVEDGLEEEIGYGLSLGKPSLVMYVQKQSGANTVDVVDRAEK
KLDEIRKILPSDVQITEIINTRDSIVKMIDNLKQSLFLGGLIVILITYLFLRSFRTSMIV
SLTIPFSLIIGFIGMYLLGYTINVISLMSLTIAIGMVVDNAIVVTENITKKLEKGEQFRK
KAAISGASEMGLAITASTLTTVVVFLPMIFAKGITKIIFGQLAVLVTITLLGSLFTALTL
APMLAAKWMSAKGKFAHSKLFTKTEEIYQSIERGYKKLLALAIDNPKKTVALMFGIFFLL
LFLVPLIGTEFLPEADNGELNIEIRLNERVRLDEGKRMVKKVAELYDKLVPEKKTYYAFV
GRTKKGVGNVLGYEEGNYIIQSGAKLVDKEKRKRSAKEVANVLRKELEKIPGIEKLSVSA
MSAYQKIFFSGGGKPISLEIYGDDLPKLREIGNRVKKEFERIPGVVDVTVSLEKPRQEIW
VKIDRVKLAKAGLTPADIAYIFRTSFYGNAASKFREGSKDFDIFVRLQDKYRTGMEDLER
IKIPLKNGKTVSLSDLVSFEQNLGPVKIERIDRERVVKVEASTYGITLGEATRKIKEALK
KTPFPPGYHYKFGGDVEEQRKAFRTLTLLLILGILLVYMVMASQFESLRQPFYIMFSIPF
TFTGVIAAFILTNTPLSLISFIGVVMLMGIVVNNAIVLVDYINLLRARGYELAEAIKEAG
QSRLRPVLMTTLTTISGTIPMALSRGEGSEMWNELGITLIGGLSVSTLITLIIVPTVYYI
FEKRKEVANG
NT seq 3093 nt   +upstreamnt  +downstreamnt
atgagactgccagaatttgccgtaaaaaaacctgtaacagttgcaatgctgtttttaggg
gtatttattttaggtgcggtgtcagtatttttcttaagcattgaccttttacccaagata
gacccccctgctatatcagtaattacaacatatcccggtgcaagtgcaactgatgttgaa
aacgatgttacaaaaattcttgaagataaattaagctcggtaaataatcttgacaaatta
ctttctacatcaaaagacaatatttctattgtaacctgtaaatttgactggggaacaaat
cttgacgttgcggcaaacgatgtaagggataagattgaccttgctatgaaggaattgcca
aaagacattgacaggcctatgatatttaaattcaactcagcaatggcacctgttttaatc
ttatctgttaacgcaaaagagagttaccctcagcttgcaaggcttgcaaaagatgttatc
gccgacaatttaaagaaagtccccggtgttggtactgttgtaattgaaggtgaaagggac
aggcaaataaatgtattttttgatcctgaaaaacttgcaacctatcaccttacaacatta
caggtaattgaggcaataaaaaagcaaaacattgatttgcctttaggctcaataaaaaca
gggataagcgaatatatgctaagaatacctgcaaggtttaaatcagcaagggaattagct
gaaatgcctgttttagtctttaatggcaaagttgtgtttttgaaagacattgcaaaggtt
gaagacggtttggaagaggaaattggctatggcctttcattaggtaaaccatcacttgtt
atgtatgttcaaaaacaatctggggcaaacactgttgatgttgttgacagggctgaaaaa
aagttagatgaaataagaaaaattcttccaagcgatgttcagattacagagataatcaac
acaagggattcaattgtgaagatgatagacaaccttaaacagagtttgtttttaggcgga
ttaatcgttattttaataacctatctgtttttgagaagtttcaggacatcaatgattgta
tcgctaacaatcccattctcactcataataggatttatagggatgtatcttttaggctat
acaattaatgttatttcccttatgtccctgactattgcaattggaatggtggtggacaat
gccattgttgtaactgaaaatataacaaaaaaacttgaaaagggagagcaattcaggaaa
aaggcggcaatttcaggtgcatctgaaatggggcttgcaattacagcatcaaccttaacc
acagttgttgtttttctcccaatgatatttgcaaagggaattacaaagattattttcggg
caattggctgttcttgtaaccatcacccttttaggctcactttttaccgctctaacactt
gctccaatgcttgccgcaaagtggatgagtgcaaaggggaaattcgcccactcaaagctt
ttcaccaaaacagaagaaatatatcaatcaattgaaaggggatataaaaaactccttgca
ctagccatagacaacccaaagaaaacagttgctttaatgtttggaatatttttccttctc
cttttccttgttccgttaataggaacagagtttcttcctgaggcagacaacggcgagtta
aacattgaaataaggctaaatgaaagggtaaggcttgacgaaggcaagagaatggtaaaa
aaggttgcagagttatacgacaaacttgtgccagagaaaaagacatactatgcatttgtt
ggaagaacaaaaaagggtgtgggaaatgttttaggttacgaagaggggaattacataatc
caatcaggtgcaaaattggttgataaggaaaagagaaaaagaagcgcaaaagaggttgca
aatgtgttgagaaaagaattggaaaagatacctggaattgaaaaactttcagtttcagca
atgagtgcatatcagaaaatatttttctcaggtggaggaaaaccaatatctcttgaaatt
tacggagacgacttgcctaaattaagggagattggcaacagggtaaaaaaagagtttgaa
agaatacctggagttgttgatgtaacagtttcccttgagaaaccgaggcaggagatatgg
gtgaaaatagacagggtaaaacttgcaaaagcagggcttacacctgcagatatagcatac
atattcagaacttccttttacggcaatgctgcttcaaagtttagagaagggtcaaaagac
tttgatatatttgtaaggcttcaggataaatacaggacaggtatggaagatttagagagg
ataaaaatacctttaaaaaacgggaaaactgtatctctttcagaccttgtttcttttgag
cagaatttagggcctgtaaaaattgaaaggattgacagggaaagagttgtaaaggttgaa
gcatcaacatatggaataaccttgggagaggcaacgagaaagattaaggaagcattgaaa
aaaacaccgttcccacctggataccattacaaatttggcggcgatgttgaagaacagagg
aaggcatttaggacattaactctgctcttaatacttggaattttacttgtctatatggta
atggcatcacagttcgaatcacttagacagccgttttacattatgttttccatacctttt
acctttacaggagtaattgctgcgtttatattaaccaataccccgctatctttaatatct
ttcatcggagtggtaatgctaatgggaattgttgttaacaacgctattgttcttgtggat
tacataaaccttctaagggcaaggggatatgaacttgcagaagcaattaaagaggccggg
cagtcaaggttaaggcctgttttaatgacaaccctaacaacaattagcggaacaatacca
atggctttaagcaggggagagggaagtgaaatgtggaatgaattgggaattaccttaatc
ggtggtttgtcagtttcaactcttattacccttataatagtgccaactgtatactatatc
tttgaaaaaagaaaagaggtggcaaatggataa

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