Thermotomaculum hydrothermale: TTHT_0779
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Entry
TTHT_0779 CDS
T06993
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
thyd
Thermotomaculum hydrothermale
Pathway
thyd00270
Cysteine and methionine metabolism
thyd00450
Selenocompound metabolism
thyd00670
One carbon pool by folate
thyd01100
Metabolic pathways
thyd01110
Biosynthesis of secondary metabolites
thyd01230
Biosynthesis of amino acids
thyd04980
Cobalamin transport and metabolism
thyd04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
thyd00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
TTHT_0779 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
TTHT_0779 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
TTHT_0779 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
TTHT_0779 (metH)
04980 Cobalamin transport and metabolism
TTHT_0779 (metH)
Enzymes [BR:
thyd01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
TTHT_0779 (metH)
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GFIT
Motif
Pfam:
S-methyl_trans
B12-binding
Pterin_bind
B12-binding_2
Motif
Other DBs
NCBI-ProteinID:
BBB32345
UniProt:
A0A7R6PX87
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Position
804642..807008
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AA seq
788 aa
AA seq
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MNRKEFIQLLFDKILILDGAYGTQLSASIKGINFPEEANIVSPETVLSLHKNYIDAGADI
IKTNTFGLFHLFNTGKIDKNYALKLLKSGVEIGVKAAKEKSVFCFASFGPMSDSIFSYSA
ETLDFFIDFYSTATELALLQGVQGILFETFSDFLELKLAVYSVRKISNSIPVIAQFTLNS
NGATIQGVDAKNCGAFLDTIDCDVAGLNCSTGPLDMALNFESFSEYISKPMSASPNAGLP
ELRNGEVYYPDIKKEFKKALSVFLKNGARIVGSCCGSNPDYTRAIKEEVNKFKGTYVKKN
KKDFLVSPDFLVDFENKSFFPIGERLNLLGNKTFKENYLKNFENAIEIEVNRQITAGAKC
LDFNVDLIARDDYLTAKRDIIALQNFAKPIISIDTLYLEVMNEVALYSACTPLYNSADLT
EKRFNFIAELYKKFGGKIIVLLMSGKKVPKTFEERLKGLELVDMFVEEYEIDKRDIFVDP
LALTLGTGVENYHYVEEIIEKSKYKTIVGLSNFSHGLPDRSRLNSFLLTNLIRRGLTASI
LDISDPNIASVIFNNEAIFEGKGFSLGEKNGLVFKGEFSKWGEYLIKGDIENLTREIISR
LEKRDKATFLLEKGLIENMEKIGSYFEKGAIYLPQLLSSAETMKNAFETLKPYLEEELAG
ENKNKNMDNARILLFTVQNDVHDIGKNIVLTVLKSFGFSVFDGGIDKSPDEIIEEINSTN
ARVVGLSALMTTSLPYMRETVKKIKESLPEVKVIVGGAVVTKRFAEEIGADGYGKNAFDA
VNLVRNLL
NT seq
2367 nt
NT seq
+upstream
nt +downstream
nt
atgaatagaaaagaatttattcaattgctttttgataaaattcttattcttgacggtgct
tatggtactcaactatccgcttctataaaaggaataaactttccagaagaagctaatata
gtgtctcctgaaacagtgttaagccttcataaaaattatattgatgcaggggcagatata
atcaaaacaaatacttttgggctatttcacctctttaataccgggaaaatagacaaaaat
tacgctttgaaactcttaaaatctggtgttgaaataggggttaaagcggcaaaagagaaa
agtgtattttgttttgccagctttggtcctatgagtgattcaatatttagttattctgct
gaaactctggacttttttatagatttttattcaactgccactgaactggcacttttgcag
ggagttcaaggcatactttttgagacattttcagactttcttgaattaaaattggcggtt
tattctgtaagaaaaatttcaaattctattccagtaattgctcaatttactctgaattca
aacggggcaacaattcagggtgttgatgcgaaaaactgtggggcatttttagatacaatt
gactgtgatgtggcagggttaaattgctctaccgggcctttagatatggctttaaacttt
gaatctttttcagaatatatttcaaagccaatgtctgcttctccaaatgcagggcttcca
gaattgagaaatggggaagtttattatcctgatattaaaaaagaatttaaaaaagcatta
tctgtatttttaaaaaatggagcaaggattgttggaagttgttgtggttcaaatccagat
tatacgagggcaattaaagaagaagttaataaatttaagggtacttatgtcaagaaaaat
aaaaaagattttttggtttctcctgattttcttgtagattttgaaaacaaatcatttttt
ccaataggcgaaaggctaaatttacttggcaataaaacatttaaagaaaattacctgaaa
aattttgaaaatgctattgaaatagaggttaacaggcagataactgcaggggctaaatgt
cttgattttaatgtagatttgattgccagagatgactatttaactgctaaaagggatata
attgctcttcaaaattttgcaaaacctataatttcaattgataccttatacctggaagtt
atgaatgaggttgctttgtattctgcttgtacccccctttacaattctgctgacttaacg
gaaaagaggtttaattttattgccgagttgtataaaaaatttgggggcaaaataatagta
cttctaatgagtggcaaaaaagtacctaaaacctttgaagaaaggcttaaaggccttgaa
ttggtggatatgtttgtagaagagtacgaaattgataaaagagatatttttgtcgatccc
cttgctttaactttgggtacaggggttgaaaactaccattatgttgaggagataattgaa
aaatcaaaatataaaacaattgttggtttatctaacttttcccacggtttacctgataga
agcaggcttaattcatttcttctaacaaatttaattagaaggggcttaactgcctctata
ttagatatttctgacccaaatattgcttcagttatttttaataacgaggctatttttgaa
gggaaaggtttttctctgggagaaaagaatggcttggtttttaaaggggaattttccaaa
tggggcgagtatctgattaaaggggatattgaaaatttaaccagagagattatttcaagg
cttgaaaaaagggataaagccacatttttacttgaaaaagggttaattgaaaatatggaa
aaaatcgggagctattttgagaagggagcaatttaccttcctcaattactctcttcagca
gaaacaatgaaaaacgcttttgagacattaaagccttatcttgaagaagagttagccggg
gaaaataaaaataaaaacatggataatgcaagaatacttctttttactgttcaaaacgat
gtgcatgatatagggaaaaatattgttttaacagttttaaagagttttggtttttctgtc
tttgatggtggtattgataaatctcctgatgagattattgaggaaattaattcaacaaat
gcaagagttgttggtttatccgctttaatgacaacaagtttaccttatatgagagaaaca
gtaaaaaaaataaaggaaagtctgccagaggttaaggtaattgtaggtggggctgttgta
acgaaaaggtttgcagaggaaattggagccgacggttatggaaaaaatgcctttgatgca
gttaaccttgtaaggaatctgttatga
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