KEGG   Thermotomaculum hydrothermale: TTHT_0779
Entry
TTHT_0779         CDS       T06993                                 
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
thyd  Thermotomaculum hydrothermale
Pathway
thyd00270  Cysteine and methionine metabolism
thyd00450  Selenocompound metabolism
thyd00670  One carbon pool by folate
thyd01100  Metabolic pathways
thyd01110  Biosynthesis of secondary metabolites
thyd01230  Biosynthesis of amino acids
thyd04980  Cobalamin transport and metabolism
thyd04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:thyd00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    TTHT_0779 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    TTHT_0779 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    TTHT_0779 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    TTHT_0779 (metH)
   04980 Cobalamin transport and metabolism
    TTHT_0779 (metH)
Enzymes [BR:thyd01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     TTHT_0779 (metH)
SSDB
Motif
Pfam: S-methyl_trans B12-binding Pterin_bind B12-binding_2
Other DBs
NCBI-ProteinID: BBB32345
UniProt: A0A7R6PX87
LinkDB
Position
804642..807008
AA seq 788 aa
MNRKEFIQLLFDKILILDGAYGTQLSASIKGINFPEEANIVSPETVLSLHKNYIDAGADI
IKTNTFGLFHLFNTGKIDKNYALKLLKSGVEIGVKAAKEKSVFCFASFGPMSDSIFSYSA
ETLDFFIDFYSTATELALLQGVQGILFETFSDFLELKLAVYSVRKISNSIPVIAQFTLNS
NGATIQGVDAKNCGAFLDTIDCDVAGLNCSTGPLDMALNFESFSEYISKPMSASPNAGLP
ELRNGEVYYPDIKKEFKKALSVFLKNGARIVGSCCGSNPDYTRAIKEEVNKFKGTYVKKN
KKDFLVSPDFLVDFENKSFFPIGERLNLLGNKTFKENYLKNFENAIEIEVNRQITAGAKC
LDFNVDLIARDDYLTAKRDIIALQNFAKPIISIDTLYLEVMNEVALYSACTPLYNSADLT
EKRFNFIAELYKKFGGKIIVLLMSGKKVPKTFEERLKGLELVDMFVEEYEIDKRDIFVDP
LALTLGTGVENYHYVEEIIEKSKYKTIVGLSNFSHGLPDRSRLNSFLLTNLIRRGLTASI
LDISDPNIASVIFNNEAIFEGKGFSLGEKNGLVFKGEFSKWGEYLIKGDIENLTREIISR
LEKRDKATFLLEKGLIENMEKIGSYFEKGAIYLPQLLSSAETMKNAFETLKPYLEEELAG
ENKNKNMDNARILLFTVQNDVHDIGKNIVLTVLKSFGFSVFDGGIDKSPDEIIEEINSTN
ARVVGLSALMTTSLPYMRETVKKIKESLPEVKVIVGGAVVTKRFAEEIGADGYGKNAFDA
VNLVRNLL
NT seq 2367 nt   +upstreamnt  +downstreamnt
atgaatagaaaagaatttattcaattgctttttgataaaattcttattcttgacggtgct
tatggtactcaactatccgcttctataaaaggaataaactttccagaagaagctaatata
gtgtctcctgaaacagtgttaagccttcataaaaattatattgatgcaggggcagatata
atcaaaacaaatacttttgggctatttcacctctttaataccgggaaaatagacaaaaat
tacgctttgaaactcttaaaatctggtgttgaaataggggttaaagcggcaaaagagaaa
agtgtattttgttttgccagctttggtcctatgagtgattcaatatttagttattctgct
gaaactctggacttttttatagatttttattcaactgccactgaactggcacttttgcag
ggagttcaaggcatactttttgagacattttcagactttcttgaattaaaattggcggtt
tattctgtaagaaaaatttcaaattctattccagtaattgctcaatttactctgaattca
aacggggcaacaattcagggtgttgatgcgaaaaactgtggggcatttttagatacaatt
gactgtgatgtggcagggttaaattgctctaccgggcctttagatatggctttaaacttt
gaatctttttcagaatatatttcaaagccaatgtctgcttctccaaatgcagggcttcca
gaattgagaaatggggaagtttattatcctgatattaaaaaagaatttaaaaaagcatta
tctgtatttttaaaaaatggagcaaggattgttggaagttgttgtggttcaaatccagat
tatacgagggcaattaaagaagaagttaataaatttaagggtacttatgtcaagaaaaat
aaaaaagattttttggtttctcctgattttcttgtagattttgaaaacaaatcatttttt
ccaataggcgaaaggctaaatttacttggcaataaaacatttaaagaaaattacctgaaa
aattttgaaaatgctattgaaatagaggttaacaggcagataactgcaggggctaaatgt
cttgattttaatgtagatttgattgccagagatgactatttaactgctaaaagggatata
attgctcttcaaaattttgcaaaacctataatttcaattgataccttatacctggaagtt
atgaatgaggttgctttgtattctgcttgtacccccctttacaattctgctgacttaacg
gaaaagaggtttaattttattgccgagttgtataaaaaatttgggggcaaaataatagta
cttctaatgagtggcaaaaaagtacctaaaacctttgaagaaaggcttaaaggccttgaa
ttggtggatatgtttgtagaagagtacgaaattgataaaagagatatttttgtcgatccc
cttgctttaactttgggtacaggggttgaaaactaccattatgttgaggagataattgaa
aaatcaaaatataaaacaattgttggtttatctaacttttcccacggtttacctgataga
agcaggcttaattcatttcttctaacaaatttaattagaaggggcttaactgcctctata
ttagatatttctgacccaaatattgcttcagttatttttaataacgaggctatttttgaa
gggaaaggtttttctctgggagaaaagaatggcttggtttttaaaggggaattttccaaa
tggggcgagtatctgattaaaggggatattgaaaatttaaccagagagattatttcaagg
cttgaaaaaagggataaagccacatttttacttgaaaaagggttaattgaaaatatggaa
aaaatcgggagctattttgagaagggagcaatttaccttcctcaattactctcttcagca
gaaacaatgaaaaacgcttttgagacattaaagccttatcttgaagaagagttagccggg
gaaaataaaaataaaaacatggataatgcaagaatacttctttttactgttcaaaacgat
gtgcatgatatagggaaaaatattgttttaacagttttaaagagttttggtttttctgtc
tttgatggtggtattgataaatctcctgatgagattattgaggaaattaattcaacaaat
gcaagagttgttggtttatccgctttaatgacaacaagtttaccttatatgagagaaaca
gtaaaaaaaataaaggaaagtctgccagaggttaaggtaattgtaggtggggctgttgta
acgaaaaggtttgcagaggaaattggagccgacggttatggaaaaaatgcctttgatgca
gttaaccttgtaaggaatctgttatga

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