KEGG   Tepidibacter hydrothermalis: P4S50_02705
Entry
P4S50_02705       CDS       T09528                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
thyr  Tepidibacter hydrothermalis
Pathway
thyr03030  DNA replication
thyr03410  Base excision repair
thyr03420  Nucleotide excision repair
thyr03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:thyr00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    P4S50_02705 (ligA)
   03410 Base excision repair
    P4S50_02705 (ligA)
   03420 Nucleotide excision repair
    P4S50_02705 (ligA)
   03430 Mismatch repair
    P4S50_02705 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:thyr03032]
    P4S50_02705 (ligA)
   03400 DNA repair and recombination proteins [BR:thyr03400]
    P4S50_02705 (ligA)
Enzymes [BR:thyr01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     P4S50_02705 (ligA)
DNA replication proteins [BR:thyr03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     P4S50_02705 (ligA)
DNA repair and recombination proteins [BR:thyr03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     P4S50_02705 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     P4S50_02705 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     P4S50_02705 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      P4S50_02705 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD PTCB-BRCT BRCT_2 RNA_ligase Nlig-Ia RNA_lig_T4_1 RNA_pol_A_CTD
Other DBs
NCBI-ProteinID: WFD11003
LinkDB
Position
629658..631685
AA seq 675 aa
MDIKKRVQEITEIINYHNHKYYVEDDPEIDDYDYDMLMNELIDIEKKYPEYKREDSPTQR
VGGAVLDKFEQVVHKTPMLSLSNAFSGNDLRDFDNRIKGVVNSDVEYVVEFKIDGLSAVI
TYENGVLKIGATRGDGSVGENVTKNLKTVKSIPMKISGNLNLQVRGEVFIPKDKFEKLNK
YQEENGLNLFANPRNAAAGSLRQLDSKIAAKRHLDMFVFNLEGIDEDKFKTHSESLEFLK
ELGFKVSSNYKVCKNIEEVIEFINYWTEHRSELKFDIDGMVIKVNDLKQREELGNTTKSP
RWAIAYKFPAEKKKTKLLDIIIQVGRTGNLTPTALLEPVQVAGSIVSRATLHNEDYIKQK
DIKIKDTVIIQKAGDVIPEVVEVVKEERDGTQVEFKMPDECPECGFETSRLEGEAAVKCM
NISCPAQIRRGIIHFVSRDAMNIDGLGERIVTLLLKENLIKDIADIYYLKKEDLVSLERM
GEKSSQNLIEAIQKSKENDLSRLVFGLGIKYIGSKGAKILAGNFDDIYKIIEAEKEDLIQ
LEEFGEIMADSVVDFFNNDKNLELIEKFKSVNVNLKSLKSESNEVKIFDGMKIVLTGTLD
KYKRNDVKEIIEKFGGKVTGSVSKSTNIVFAGREAGSKLDKANSLGIKVIDENTFDEIIK
LSSKEEVQKHLDMSN
NT seq 2028 nt   +upstreamnt  +downstreamnt
atggatattaaaaaaagagtacaagaaattactgaaattataaattatcataatcataag
tactatgttgaggatgatcctgagattgatgattatgattatgatatgttgatgaatgag
cttatagatatagagaaaaaatatccagaatataaaagagaggattctccaactcaaaga
gttggtggggcagtacttgataaatttgaacaagtagtacataagactcctatgctaagt
ctttccaatgcgttttcgggtaatgatttgagagattttgacaatagaataaaaggtgta
gtaaatagtgatgttgaatatgtagtagaatttaagatagatggattatctgcagttata
acttatgaaaatggagttttgaaaattggtgcaactcgtggggatggttctgttggagaa
aatgtaactaagaacttaaagactgtaaagagtatacctatgaaaattagtgggaatctg
aatttgcaggtaagaggagaagtatttataccaaaagataaattcgaaaagcttaataaa
tatcaagaagaaaatggattgaatttatttgcaaatcctagaaatgcagctgcaggttca
ttaagacaacttgattctaagattgctgcaaagagacatttagatatgtttgtattcaat
cttgaaggaatagatgaagataaatttaaaactcacagtgaaagtttagaatttttgaaa
gaattaggatttaaagttagctctaattataaagtttgcaagaatatagaagaagttata
gaatttataaattattggacagagcatagatcagagctgaagtttgatatagatggtatg
gttataaaggttaatgatttaaagcaaagagaagaattaggtaatacaactaaaagtcct
cgttgggcaatagcttataaattccctgctgaaaagaaaaagactaaattactagatata
ataattcaggttggaagaacgggaaatcttacaccaacagccttacttgagccagttcaa
gttgcaggatctatagtatcaagagcaacactgcataatgaagattatataaaacaaaag
gatattaaaatcaaagatacggttataatacaaaaagctggagatgtgataccagaggtt
gtagaagttgttaaagaagagagagatggtacacaagtagaatttaaaatgcctgatgaa
tgcccggagtgtggatttgaaactagtagattagagggagaagcagctgttaagtgtatg
aacatatcttgtcctgctcaaataagaagagggatcatacattttgtatcaagagatgct
atgaatatagatggattaggagaacgaatagtaactcttttattaaaagaaaatttaata
aaagatatagcagatatttattacttgaaaaaagaagatttagtctctcttgagagaatg
ggtgaaaagtcttctcaaaatttaatagaggctatacaaaaatcaaaagaaaatgatttg
tctagattagtattcggtttaggaataaagtatataggaagtaagggtgctaaaatactt
gcgggtaattttgacgatatatacaaaataatagaagctgagaaagaggatttaattcaa
cttgaagaatttggagagattatggctgatagtgtagttgatttcttcaataacgataag
aatttagaacttatagagaaatttaagtctgtaaatgtaaacttgaaatcattaaaaagt
gaaagtaatgaggttaaaatatttgatggaatgaagattgttttaacaggaacacttgat
aaatataagagaaatgatgttaaagaaataatagaaaaattcggtggtaaagtaacggga
agtgtaagtaaatcaacgaatatagtatttgcaggtagagaagctggatctaagcttgat
aaggctaattctcttggcataaaagttatagatgaaaatacatttgatgaaataataaag
ctatcttctaaggaagaagttcaaaaacatttagatatgagtaactaa

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