KEGG   Thermoanaerobacter kivui: TKV_c05890
Entry
TKV_c05890        CDS       T03397                                 
Symbol
ligA
Name
(GenBank) DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
tki  Thermoanaerobacter kivui
Pathway
tki03030  DNA replication
tki03410  Base excision repair
tki03420  Nucleotide excision repair
tki03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:tki00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    TKV_c05890 (ligA)
   03410 Base excision repair
    TKV_c05890 (ligA)
   03420 Nucleotide excision repair
    TKV_c05890 (ligA)
   03430 Mismatch repair
    TKV_c05890 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tki03032]
    TKV_c05890 (ligA)
   03400 DNA repair and recombination proteins [BR:tki03400]
    TKV_c05890 (ligA)
Enzymes [BR:tki01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     TKV_c05890 (ligA)
DNA replication proteins [BR:tki03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     TKV_c05890 (ligA)
DNA repair and recombination proteins [BR:tki03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     TKV_c05890 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     TKV_c05890 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     TKV_c05890 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      TKV_c05890 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 Nlig-Ia DNA_ligase_ZBD RNA_ligase PTCB-BRCT HHH BRCT_2 HHH_8 HHH_3 CoA_binding_2 Mur_ligase_M Cdd1
Other DBs
NCBI-ProteinID: AIS51785
UniProt: A0A097APP4
LinkDB
Position
582294..584282
AA seq 662 aa
MEPKERIKELREKINYHNYRYYVLDQPEISDYEYDMLMRELIELEEKYPELKTPDSPSQR
VGGEPLKEFEPFTHVVPMLSLANAFSEGELRDFDRRVREAVGDVEYVVELKIDGLSVELI
YENGIFTVGSTRGDGIVGENVTQNLKTIKSIPLRLKDDVSLVVRGEVFMPRTSFEKLNEE
REKLGESLFANPRNAAAGSLRQLDPKVTAKRDLDIFIFNLQKIEDRKFKTHIETLEFLKE
QGFKVIPIHKKCSNIDEVIKEIEEIRNLRDKLPYDIDGAVVKVNELEKREILGQTAKDPR
WAIAFKYPAERKKTKVLDIIVQVGRTGALTPTAILEPVTISGSVVSRATLHNEDYIKEKD
IRIGDTVIVQKAGEIIPEVVEVVKEERTGQEREFVMPDRCPECGALAVRLPGETIRRCTG
LNCPAQLLRGIIHFASKDAMDIEGLGPAIINQLLSKGLIHNIADLYYLKYEDLIQLERMG
DKSVKNLLNAIEESKTRDLDRLLFGLGINLIGSKAAQVIAEHFKTMDNIMKAKFEDFTHL
PDIGPKMARSIVSFFAEKQNLEIIEKLKNAGVNMKKLSKEKVSNIFEGKTFVLTGALENY
TREEATRMIEERGGKVTNSVSKKTDYVLVGKDPGSKLKKAQELGIKIIDEKQFEEMLKGE
NI
NT seq 1989 nt   +upstreamnt  +downstreamnt
atggagccaaaagaaaggataaaggaattgagagaaaaaataaattatcacaattacaga
tattacgttttggaccaaccagagatttcagactatgagtacgacatgctgatgagagaa
cttatagaattagaagaaaaatatccagagcttaaaactccagactctccatcccaaaga
gtaggtggggagcctttaaaagaatttgagccttttacccatgtagttccaatgttaagt
ttggctaatgctttttctgagggagaacttagagactttgatagaagagtaagagaggca
gtgggagatgtagagtacgtagtagaattaaaaattgacggtttatctgtggaactaatt
tatgaaaatggcatatttactgtaggttctacaagaggagacgggatcgtaggagaaaat
gtcacacaaaatttaaagactataaagtcaattcctttaaggcttaaggatgatgtgagc
cttgttgtaagaggagaggtcttcatgccacgcacttcttttgaaaaattaaatgaggag
agagaaaaattaggggaaagcctttttgcaaatcccagaaatgctgcagcaggttcttta
aggcaattagatcctaaagtgacggcgaaaagagatttagacatttttatttttaacctt
cagaagattgaggatagaaaatttaaaactcacatagagacattagaatttttgaaagaa
caaggatttaaagtaataccaattcataaaaaatgtagcaatatagatgaagtaataaaa
gaaatagaagagataagaaacttacgagataagctgccttacgacattgatggagcagtt
gtaaaagtaaatgaacttgaaaagagagaaattttaggacagactgcaaaagaccccagg
tgggctattgcttttaaatatcctgctgagaggaaaaagacaaaagtcttggatataata
gttcaagtaggaaggactggagctcttactcctacagctatattagagcctgtaactatt
tcaggttcagttgtgagccgagctacacttcataatgaagattacataaaagagaaagac
ataaggataggagatacggtaatagttcaaaaagcgggagaaatcattcctgaagtagta
gaagtggtaaaagaagagaggactggacaagaaagagagtttgtaatgccagatagatgc
cctgaatgcggtgctttagctgtgaggcttccgggggagactataaggcgttgtacaggt
ctaaattgtcctgcacagcttctaagaggcattatccactttgcttcaaaagatgcaatg
gatatagaaggattggggccagctataataaatcagcttttgtcaaaaggtctaattcac
aacatagcagatttgtattatcttaaatacgaagatttaatacaattagaaagaatggga
gacaaatctgttaaaaatttattaaatgctattgaagaaagcaaaacaagagatttagat
agattgctctttggcttgggtataaacttaataggcagtaaagctgcccaagtgattgct
gagcattttaagacaatggacaatatcatgaaggcaaaatttgaagactttacacatttg
cctgacataggacctaagatggcaagaagcatagtttccttttttgcagaaaaacaaaat
ttagagataattgaaaaacttaaaaatgctggagtaaacatgaaaaagctttcaaaagaa
aaagtaagcaacatatttgaagggaaaacttttgttttgacaggagcgttggaaaattac
acgagagaagaagctaccagaatgattgaagaaagaggtggaaaagttacaaattcagta
agtaaaaaaacggactatgtattagtaggtaaagatcctggttctaaacttaaaaaagcc
caagaattaggaataaagataattgatgaaaaacaatttgaagaaatgctaaaaggtgaa
aatatttaa

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