Thermococcus kodakarensis: TK0181
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Entry
TK0181 CDS
T00226
Name
(GenBank) 3-hydroxy-3-methylglutaryl-CoA synthase
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
tko
Thermococcus kodakarensis
Pathway
tko00280
Valine, leucine and isoleucine degradation
tko00650
Butanoate metabolism
tko00900
Terpenoid backbone biosynthesis
tko01100
Metabolic pathways
tko01110
Biosynthesis of secondary metabolites
Module
tko_M00849
C5 isoprenoid biosynthesis, mevalonate pathway, archaea
Brite
KEGG Orthology (KO) [BR:
tko00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
TK0181
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
TK0181
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
TK0181
Enzymes [BR:
tko01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
TK0181
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Paralog
Gene cluster
GFIT
Motif
Pfam:
ACP_syn_III_C
HMG_CoA_synt_C
ACP_syn_III
Thiolase_N
HMG_CoA_synt_N
PTCRA
Motif
Other DBs
NCBI-ProteinID:
BAD84370
UniProt:
Q5JFL6
LinkDB
All DBs
Position
complement(150879..151931)
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AA seq
350 aa
AA seq
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MSKLLKPKREVGIIGYGAYVPMYRIKAEEIGRVWGVSSFPIQEKSVPGLDEDTITIGIEA
ARNALKRAQIDPKLIRAIWLGTESKPYAVKPSGTVIAEAIGATPDLDAADFEFACKAGTE
AIQAAIGFVGSGMADYAMAIGADTSQGRPGDHLEFTAAAGGAAYILAPKSSETLAYFEAS
YSYVTDTPDFWRRQHEHYPRHGNRFTGEPAYFHQIINAAKTLMEELGYTPNDFDYAVFHQ
PNVKFPLTAAKILGFPKEKVLPGLLSGIIGNTYSGATLVGVSAVLDIAKPGDRILWVSFG
SGAGSDAFSLVVQDAIEEKRDLAPKTMDYVNRKKYIDYALYAKHRGKYIL
NT seq
1053 nt
NT seq
+upstream
nt +downstream
nt
atgagcaaactcctgaagcccaagagggaggtcggcattatcggctacggcgcctacgtg
ccgatgtatagaatcaaggcagaggagataggaagggtctggggagttagcagcttcccg
atccaggagaagtccgtccccggtcttgatgaggatacgataacaatcggcattgaagcc
gcgagaaacgccctcaagagggcccagatcgaccctaagcttatcagggccatctggctc
ggaaccgagagcaagccctacgccgtcaagccgagcggaacggttatagccgaggcaatt
ggtgcaacgccagatttagatgccgctgactttgagtttgcctgcaaggccggaaccgag
gctatacaggcagctattggcttcgtcggttcgggaatggccgactacgcgatggctatc
ggtgcagacacctcgcagggcaggcccggcgaccaccttgagttcacggccgcggcagga
ggagccgcctacattctcgctccaaagagctccgagaccctggcttacttcgaggcgagc
tactcatacgtcaccgacacccccgacttctggaggaggcagcacgagcactacccgagg
cacggtaaccgcttcacaggtgagcccgcctacttccaccagataataaacgccgcaaag
accctcatggaggagctcggctacacgccgaacgacttcgactacgccgtcttccaccag
ccgaacgtcaagttcccgctcaccgccgccaaaatcctcggcttcccgaaggagaaggtc
cttccaggactcctcagcggaataataggcaacacatacagcggcgctaccctcgtgggt
gtatcggcggttctcgacatagccaagcccggcgacaggattctgtgggtaagctttggt
tcaggagctggaagtgacgcattcagcctcgtcgtccaggacgcgatagaggagaagagg
gacctggctccaaagaccatggactacgtgaacagaaagaagtacatagactacgccctc
tacgcgaagcacaggggcaagtacatactgtga
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