KEGG   Thioclava litoralis: RPE78_11585
Entry
RPE78_11585       CDS       T10820                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
tlb  Thioclava litoralis
Pathway
tlb03030  DNA replication
tlb03410  Base excision repair
tlb03420  Nucleotide excision repair
tlb03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:tlb00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    RPE78_11585 (ligA)
   03410 Base excision repair
    RPE78_11585 (ligA)
   03420 Nucleotide excision repair
    RPE78_11585 (ligA)
   03430 Mismatch repair
    RPE78_11585 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tlb03032]
    RPE78_11585 (ligA)
   03400 DNA repair and recombination proteins [BR:tlb03400]
    RPE78_11585 (ligA)
Enzymes [BR:tlb01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     RPE78_11585 (ligA)
DNA replication proteins [BR:tlb03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     RPE78_11585 (ligA)
DNA repair and recombination proteins [BR:tlb03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     RPE78_11585 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     RPE78_11585 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     RPE78_11585 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      RPE78_11585 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden OB_DNA_ligase HHH_2 BRCT DNA_ligase_ZBD HHH_5 PTCB-BRCT Nlig-Ia
Other DBs
NCBI-ProteinID: WRY33317
UniProt: A0ABZ1DX08
LinkDB
Position
2353187..2355310
AA seq 707 aa
MNSSAIPPGDMTKDTAAREIADLSVRLERANTAYHTQDAPEISDAEYDAFKRRLLALEAQ
FPDLQRGDSPSQKVGAAPAEGFAKVRHEQRMMSLGNAFEDEDVEDFVRGIRKYLGLAADT
PLSFTAEPKIDGLSLSLRYEKGVLVYAATRGDGETGENVTENARTIPDIPQHLKDAPDLL
EVRGEVYMAHDDFAALNISQDERGEKRFANPRNAAAGSLRQLDPRVTARRPLKFFAYAWG
VLSAPLADTQSGAIKRLAELGFSTNPLTKTCSGSAQMIAQYHAIEADRAMLGYDIDGVVY
KVNDLALQARLGFRSTTPRWAIAHKFPAELAWTQLEKIEIQVGRTGALSPVARLTPVTVG
GVVVSNATLHNEDYIAGRDSKGEEIRGGRDIREGDWVQVYRAGDVIPKIADVDLARRAEG
LQPYEFPSKCPECGSDAIREEGDAVRRCTGGLICPAQQVEKLKHFVSRAAFDIDGLGAKQ
VEAFYEDGWVREPVDIFTLRDRYGPGQVRQLKNRDGWGEKSALKLFDAIDQRRDIALARV
IFALGIRHVGEQTATLLARHYGTWPSFEAAMTQADPKGNAAWEDLLGIDGVGKVLAESLV
STFHQEAERGSIDRLIAQLRVQEAEKPKNDSEIAGLTIVFTGTLEKMTRSEAKARAEALG
AKVAGSVSKKTDILVAGPGAGSKATKAADLGVRVIDEDAWLVMAGQG
NT seq 2124 nt   +upstreamnt  +downstreamnt
atgaattcttccgccattccccccggtgatatgacaaaagatacggcggcacgcgagatt
gcggacctatcggtgcggcttgaacgggcgaatacggcgtatcacacgcaggatgcgccg
gagatttctgacgccgaatatgatgcgtttaaacgccgccttcttgcattggaggcgcaa
ttcccggatctgcaacgtggcgacagcccgtcccagaaagtaggcgcggccccggcggaa
gggtttgcgaaggtccggcatgaacaacggatgatgagcttgggcaatgccttcgaggat
gaagatgtcgaggattttgtccgtggcatccggaaatatctcggattggcagcggatacg
cccttgtcttttaccgcagagccaaaaattgacgggctatcgctttcgttgcgttatgaa
aaaggtgtgcttgtttacgctgcaacgcgtggcgatggggaaacgggtgaaaacgttaca
gaaaatgcgcggacgattcccgatattccgcagcatttgaaagatgcgccggatctcctt
gaggtgcgcggcgaggtgtatatggcgcatgacgattttgcggcgctcaatatctcgcaa
gatgaacggggcgagaaacgttttgccaatccgcggaatgccgccgcagggtcgttgcgc
cagctggatccgcgggtcaccgcacgcagaccattgaagttttttgcctatgcttggggg
gtgctgtcggctcctcttgcagatacccaaagcggagcgatcaagcgtttggccgaactt
ggtttttcgacgaatccgctgaccaagacctgttccggatcggcgcagatgattgcccag
tatcatgcgatcgaagcagatcgggcgatgctcggctatgatattgacggtgtcgtctat
aaggtcaacgaccttgcgttgcaggctcggctaggctttcgttcgacaacgccgcgttgg
gcgatcgcacataaattccctgccgaactggcatggacccaacttgagaagatcgagatt
caggtggggcggactggtgcactcagtcccgtggcgcgtctgacaccggtcacggttgga
ggtgtggttgtctccaacgcgaccttgcataacgaagactatattgcagggcgcgattcg
aaaggcgaagagatccgtggcgggcgcgacatccgcgagggggattgggtgcaggtttat
cgcgcaggcgatgtgatcccgaaaattgcggatgtggatcttgcgcgtcgcgcggaaggt
ctgcaaccctatgaatttccttcgaaatgccctgaatgtggttcggacgccattcgcgag
gaaggggatgcggtgcgtcggtgcaccggcggattgatctgtccggcgcagcaagttgaa
aagctcaagcattttgtctcgcgcgctgcgttcgatattgacgggcttggcgccaaacag
gttgaggcgttttatgaagatggctgggtcagggaacctgtcgacattttcactctgcgg
gacagatatgggccgggtcaggtgcggcaattgaaaaatcgcgatggttggggggagaaa
tccgcgctcaaactgtttgacgcgattgaccagcggcgtgatatcgcgcttgcgcgtgtg
atctttgctttggggatccgtcatgtgggagaacagaccgcgacgttgctggcgcgccat
tatggcacatggccgtctttcgaagccgcaatgacgcaggccgatccgaaaggcaatgca
gcctgggaggatctgcttggcattgacggtgttggcaaggttcttgccgaaagtctggtg
agcaccttccatcaggaagccgagcgcgggtcgattgaccgtctgatcgcgcagcttcgg
gtgcaagaggccgaaaagccgaaaaatgatagcgaaatcgcagggttgacgatcgtattt
accggaacgcttgaaaagatgacacgttcggaagccaaggcgcgggccgaggcgctgggg
gcaaaagtggcggggtccgtgtcgaagaagaccgatatccttgtggccggtccgggggcc
ggatccaaggcaaccaaagcggcagatcttggtgtgcgggtgattgatgaggatgcgtgg
ctggttatggccgggcaaggctga

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