KEGG   Thiomicrospira microaerophila: JX580_06410
Entry
JX580_06410       CDS       T08259                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
tmh  Thiomicrospira microaerophila
Pathway
tmh03030  DNA replication
tmh03410  Base excision repair
tmh03420  Nucleotide excision repair
tmh03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:tmh00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    JX580_06410 (ligA)
   03410 Base excision repair
    JX580_06410 (ligA)
   03420 Nucleotide excision repair
    JX580_06410 (ligA)
   03430 Mismatch repair
    JX580_06410 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tmh03032]
    JX580_06410 (ligA)
   03400 DNA repair and recombination proteins [BR:tmh03400]
    JX580_06410 (ligA)
Enzymes [BR:tmh01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     JX580_06410 (ligA)
DNA replication proteins [BR:tmh03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     JX580_06410 (ligA)
DNA repair and recombination proteins [BR:tmh03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     JX580_06410 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     JX580_06410 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     JX580_06410 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      JX580_06410 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 HHH_5 BRCT Nlig-Ia DNA_ligase_ZBD HHH PTCB-BRCT 5_3_exonuc
Other DBs
NCBI-ProteinID: UQB41332
LinkDB
Position
complement(1306135..1308162)
AA seq 675 aa
MIPIAEQVAQLREQLESHNYAYYVLDEPSISDAQYDALYRQLIALETEHPELITTESPTQ
RVGGKVKSGFQEVRHTVPMLSLDNAFSDEELAEFNQRVAARLSKQIPLVYAAEPKMDGLA
VNLRYQQGRLVQAATRGDGELGEDVTHNVRTIRAIPLKLCGSGWPDVLEVRGEVFMHKAA
LDKINQAQLERGDRPFANPRNAAAGSLRQLDPTITAQRPLSFFCYGWGQVSDDFKLPACY
SEMLDLLKTWGLPINPLASLVEDQAGLVNYYQDLFALRATLPYEIDGIVYKLDRLEGQQA
LGFTSKFPRWAIARKFPAQEVWTKLLAIDVQVGRTGALTPVARLEPVLVGGVMVSNATLH
NMDEIKRRDVRIGDTVIVRRAGDVIPEVVAPVLSQRPENTALFEMPVACPECGSDVVKEL
DKAVYCCTGGLFCPAQRKRALAHFVSRKAMDIQGLGEKLIDQLVSAGLVAHPDDFYKLNS
DELLQLERMASKSAQKVIDAIDASKSTTLPRFIYALGIPEVGEVTAKNLAQHFKTLDALM
QASLKQLLSVADVGEIVAHHLIQFFAQAHNLEVIEGLLSAGVSWPLIETPISSLDSVFSG
KTCVLTGSLQQMTREQAKAELENLGAKVSSAISAKTDYLIAGEKAGSKLAKAEVLGVNVL
TEAEFIELLGEQLDG
NT seq 2028 nt   +upstreamnt  +downstreamnt
atgatccctattgccgagcaggttgcgcaacttcgtgaacaactggagtcgcataactac
gcttactatgttctagacgaacccagtatttctgatgctcagtatgatgcattgtatcga
cagcttattgcgctcgaaactgaacatcctgagcttatcacaaccgaatcaccaacccaa
cgcgttggcggcaaagtaaagtccggttttcaggaggtgcgccatactgttccgatgcta
tcgctggataatgcatttagtgatgaagaattagctgagtttaatcagcgtgtggctgct
cgcttgtctaagcagattccgcttgtttatgctgctgagcccaaaatggatggcttagcg
gttaatttgcggtatcagcagggacgattggttcaggcggcaacccgaggcgatggtgag
ttaggcgaggacgtaacgcataacgtgcgaaccattcgtgctattccgcttaaactttgt
ggctcaggctggcctgacgtcttggaggtgcgtggtgaagtgtttatgcataaagccgca
ctcgataaaattaaccaggcgcagttagaaagaggggatagaccttttgctaatccacga
aatgctgctgcaggcagtttgcgtcagttagatccgacgattactgctcagcgaccttta
agctttttttgttacggctggggtcaagtcagtgatgattttaaactgcctgcttgctat
agcgaaatgttagacttgctaaaaacctggggcttgccaattaatcctttggctagtctg
gtggaggatcaagcaggcctggtgaactactatcaggatttatttgctttacgtgctacg
cttccctatgagattgatggcattgtttataagctagatcggcttgagggtcagcaggct
ttaggttttacatcaaagtttccacgttgggcgattgcacgtaagtttccggctcaggag
gtttggaccaaattgttagcgattgatgtccaagtcggacgaaccggcgcattaaccccg
gtcgcgcgtttagagccggtgttagtcggtggtgttatggtatctaatgccaccttacat
aatatggatgaaatcaagcgcagggatgtgcgtattggtgacacggtgattgttcggcgc
gctggtgatgtgattcctgaagtggtggcaccggttttgagtcagcgacccgaaaatacc
gctttgtttgaaatgccggttgcttgtcctgaatgtggctccgatgtggttaaagaacta
gataaggcggtctattgttgcactggtggtttattttgccctgcacagcgtaagcgcgcc
ttagcccattttgtttcgcgtaaagcgatggatattcagggcttgggtgaaaagttgatt
gatcagctggtttcagcaggcctggttgcccaccctgatgatttttataaactcaatagt
gatgaattgcttcagttagagcgtatggcaagcaagtcggcgcaaaaggtgattgatgcg
attgatgcttcaaagtcaacgacgttaccgcgttttatttatgccttaggcatccctgaa
gtcggtgaggtgacagccaaaaatctggcacagcattttaaaacactcgatgccctcatg
caggcaagcctaaaacaactgctgtctgtagcggatgtgggggagattgtagcgcatcat
ttgatacagttttttgcccaagcccataaccttgaggtgattgagggcttattgtctgcc
ggggtaagttggccattgattgaaacaccgatcagttcgttggattcggtattcagtgga
aaaacctgtgttttgacaggaagtttacagcagatgacacgcgagcaggctaaagctgaa
cttgaaaacttaggcgctaaggtgtcgagcgcgatttctgctaagacggattatctgatt
gccggtgaaaaagccggctcaaagttggccaaagccgaggttttgggggtcaatgttttg
accgaagcggaatttattgaattactaggagagcagctggatggttag

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